SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kg9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q13_A_TESA501_1
(PROSTAGLANDIN-E2
9-REDUCTASE)		 5kg9 ANTIBODY RE505-22
FAB LIGHT CHAIN
(Homo
sapiens;
Mus
musculus) 		4 / 6 TYR L 173
HIS L 198
GLU L  83
PRO L  80
 None
 1.38A 1q13A-5kg9L:
undetectable		 1q13A-5kg9L:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 5kg9 ANTIBODY RE505-22
FAB LIGHT CHAIN
(Homo
sapiens;
Mus
musculus) 		5 / 12 LEU L  50
LEU L  73
ILE L  87
GLY L  99
LEU L   4
 None
 1.25A 4j26A-5kg9L:
undetectable		 4j26A-5kg9L:
25.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_2
(MDR769 HIV-1
PROTEASE)		 5kg9 ANTIBODY RE505-22
FAB LIGHT CHAIN
(Homo
sapiens;
Mus
musculus) 		4 / 6 ASN L 171
ASP L  82
GLY L  15
PRO L 110
 None
 0.92A 4l1aB-5kg9L:
undetectable		 4l1aB-5kg9L:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 5kg9 ANTIBODY RE505-22
FAB LIGHT CHAIN
(Homo
sapiens;
Mus
musculus) 		3 / 3 LYS L  19
SER L  63
SER L  65
 None
 1.01A 6gbfA-5kg9L:
undetectable		 6gbfA-5kg9L:
18.24