SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kiq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 5kiq PLATELET-BINDING
GLYCOPROTEIN
(Streptococcus
sanguinis) 		3 / 3 TRP A 302
GLU A 334
TYR A 368
 None
 0.87A 2a3aA-5kiqA:
undetectable		 2a3aA-5kiqA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5kiq PLATELET-BINDING
GLYCOPROTEIN
(Streptococcus
sanguinis) 		4 / 7 PHE A 273
ILE A 366
GLY A 328
TRP A 302
 None
 0.97A 2y7kA-5kiqA:
undetectable		 2y7kA-5kiqA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_A_VDNA1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5kiq PLATELET-BINDING
GLYCOPROTEIN
(Streptococcus
sanguinis) 		5 / 12 ILE A 366
ILE A 349
VAL A 326
PHE A 273
PHE A 364
 None
 1.08A 3b2rA-5kiqA:
undetectable		 3b2rA-5kiqA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5kiq PLATELET-BINDING
GLYCOPROTEIN
(Streptococcus
sanguinis) 		5 / 12 ASN A 376
ILE A 436
THR A 437
VAL A 441
PRO A 380
 None
 1.01A 3kpbA-5kiqA:
undetectable		 3kpbA-5kiqA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 5kiq PLATELET-BINDING
GLYCOPROTEIN
(Streptococcus
sanguinis) 		4 / 8 ILE A 426
TYR A 428
ASP A 430
SER A 432
 None
 0.39A 3pwwA-5kiqA:
undetectable		 3pwwA-5kiqA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5kiq PLATELET-BINDING
GLYCOPROTEIN
(Streptococcus
sanguinis) 		3 / 3 PRO A 429
ASP A 430
GLU A 271
 None
 0.87A 3v4tC-5kiqA:
undetectable		 3v4tC-5kiqA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WAR_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA)		 5kiq PLATELET-BINDING
GLYCOPROTEIN
(Streptococcus
sanguinis) 		4 / 8 VAL A 326
VAL A 324
ILE A 259
ILE A 349
 None
 0.73A 3warA-5kiqA:
undetectable		 3warA-5kiqA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)		 5kiq PLATELET-BINDING
GLYCOPROTEIN
(Streptococcus
sanguinis) 		3 / 3 ILE A 426
THR A 425
PRO A 377
 None
 0.62A 6ncsA-5kiqA:
undetectable		 6ncsA-5kiqA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)		 5kiq PLATELET-BINDING
GLYCOPROTEIN
(Streptococcus
sanguinis) 		3 / 3 ILE A 436
THR A 437
PRO A 380
 None
 0.58A 6ncsA-5kiqA:
undetectable		 6ncsA-5kiqA:
20.20