SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kja'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 HIS A 304
HIS A 484
HIS A 183
GLU A 150
HIS A 238
 FE2  A 502 (-3.8A)
FE2  A 502 (-4.0A)
FE2  A 502 (-4.0A)
None
FE2  A 502 (-4.5A)
 1.28A 1a4lC-5kjaA:
undetectable		 1a4lC-5kjaA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		4 / 7 HIS A 238
HIS A 183
HIS A 304
THR A 136
 FE2  A 502 (-4.5A)
FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
None
 0.96A 1am6A-5kjaA:
undetectable		 1am6A-5kjaA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		4 / 7 HIS A 238
HIS A 183
LEU A 483
THR A 136
 FE2  A 502 (-4.5A)
FE2  A 502 (-4.0A)
None
None
 1.07A 1am6A-5kjaA:
undetectable		 1am6A-5kjaA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 ALA A 247
ILE A 242
PHE A 240
PHE A 249
LEU A 215
 None
 1.16A 1dtlA-5kjaA:
undetectable		 1dtlA-5kjaA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 183
HIS A 304
HIS A 238
 FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
FE2  A 502 (-4.5A)
 0.58A 1rjoA-5kjaA:
undetectable		 1rjoA-5kjaA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKY_A_CUA801_0
(LYSYL OXIDASE)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 183
HIS A 304
HIS A 238
 FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
FE2  A 502 (-4.5A)
 0.59A 1rkyA-5kjaA:
undetectable		 1rkyA-5kjaA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		5 / 9 ALA A  77
TYR A  51
LEU A  50
TRP A 487
GLY A  48
 None
 1.40A 1ru9H-5kjaA:
undetectable
1ru9L-5kjaA:
undetectable		 1ru9H-5kjaA:
17.87
1ru9L-5kjaA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUA_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		5 / 10 ALA A  77
TYR A  51
LEU A  50
TRP A 487
GLY A  48
 None
 1.44A 1ruaH-5kjaA:
undetectable
1ruaL-5kjaA:
undetectable		 1ruaH-5kjaA:
17.87
1ruaL-5kjaA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUL_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		5 / 9 ALA A  77
TYR A  51
LEU A  50
TRP A 487
GLY A  48
 None
 1.46A 1rulH-5kjaA:
undetectable
1rulL-5kjaA:
undetectable		 1rulH-5kjaA:
17.87
1rulL-5kjaA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 183
HIS A 304
HIS A 238
 FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
FE2  A 502 (-4.5A)
 0.59A 1w2zA-5kjaA:
undetectable		 1w2zA-5kjaA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 183
HIS A 304
HIS A 238
 FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
FE2  A 502 (-4.5A)
 0.58A 1w2zB-5kjaA:
undetectable		 1w2zB-5kjaA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 183
HIS A 304
HIS A 238
 FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
FE2  A 502 (-4.5A)
 0.59A 1w2zC-5kjaA:
undetectable		 1w2zC-5kjaA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 183
HIS A 304
HIS A 238
 FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
FE2  A 502 (-4.5A)
 0.57A 1w2zD-5kjaA:
undetectable		 1w2zD-5kjaA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_A_IPHA2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		4 / 5 HIS A 478
PRO A 480
TYR A 448
TYR A  24
 None
 1.15A 2ombA-5kjaA:
undetectable
2ombB-5kjaA:
undetectable		 2ombA-5kjaA:
18.11
2ombB-5kjaA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		4 / 7 TYR A  24
HIS A 478
PRO A 480
TYR A 448
 None
 1.10A 2ombC-5kjaA:
undetectable
2ombD-5kjaA:
undetectable		 2ombC-5kjaA:
18.11
2ombD-5kjaA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 183
HIS A 304
HIS A 238
 FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
FE2  A 502 (-4.5A)
 0.61A 2oqeA-5kjaA:
undetectable		 2oqeA-5kjaA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 183
HIS A 304
HIS A 238
 FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
FE2  A 502 (-4.5A)
 0.62A 2oqeB-5kjaA:
undetectable		 2oqeB-5kjaA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 183
HIS A 304
HIS A 238
 FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
FE2  A 502 (-4.5A)
 0.61A 2oqeC-5kjaA:
undetectable		 2oqeC-5kjaA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 183
HIS A 304
HIS A 238
 FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
FE2  A 502 (-4.5A)
 0.61A 2oqeD-5kjaA:
undetectable		 2oqeD-5kjaA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 183
HIS A 304
HIS A 238
 FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
FE2  A 502 (-4.5A)
 0.60A 2oqeF-5kjaA:
undetectable		 2oqeF-5kjaA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 183
HIS A 304
HIS A 238
 FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
FE2  A 502 (-4.5A)
 0.51A 2w0qA-5kjaA:
undetectable		 2w0qA-5kjaA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 183
HIS A 304
HIS A 238
 FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
FE2  A 502 (-4.5A)
 0.53A 2w0qB-5kjaA:
undetectable		 2w0qB-5kjaA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 238
HIS A 183
HIS A 304
 FE2  A 502 (-4.5A)
FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
 0.74A 3ag4A-5kjaA:
undetectable		 3ag4A-5kjaA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		5 / 10 HIS A 238
HIS A 183
HIS A 304
THR A 136
PRO A  55
 FE2  A 502 (-4.5A)
FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
None
None
 1.21A 3cajA-5kjaA:
undetectable		 3cajA-5kjaA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		5 / 10 HIS A 238
HIS A 183
HIS A 304
THR A 136
PRO A  55
 FE2  A 502 (-4.5A)
FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
None
None
 1.24A 3dcwA-5kjaA:
undetectable		 3dcwA-5kjaA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		5 / 10 HIS A 304
HIS A 238
HIS A 183
THR A 136
PRO A 482
 FE2  A 502 (-3.8A)
FE2  A 502 (-4.5A)
FE2  A 502 (-4.0A)
None
None
 1.30A 3dcwA-5kjaA:
undetectable		 3dcwA-5kjaA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		5 / 10 HIS A 238
HIS A 183
HIS A 304
THR A 136
PRO A  55
 FE2  A 502 (-4.5A)
FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
None
None
 1.20A 3dd0A-5kjaA:
undetectable		 3dd0A-5kjaA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 PHE A  69
LEU A 483
GLY A  73
GLY A  54
ALA A 134
 None
 1.14A 3dh0B-5kjaA:
undetectable		 3dh0B-5kjaA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		4 / 4 GLU A 409
GLY A 411
THR A 412
GLU A 413
 None
 1.01A 3e9xA-5kjaA:
undetectable		 3e9xA-5kjaA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 183
HIS A 304
HIS A 238
 FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
FE2  A 502 (-4.5A)
 0.63A 3hiiA-5kjaA:
undetectable		 3hiiA-5kjaA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_CUB801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 183
HIS A 304
HIS A 238
 FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
FE2  A 502 (-4.5A)
 0.61A 3hiiB-5kjaA:
undetectable		 3hiiB-5kjaA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		5 / 11 HIS A 238
HIS A 183
HIS A 304
THR A 136
PRO A  55
 FE2  A 502 (-4.5A)
FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
None
None
 1.22A 3mdzA-5kjaA:
undetectable		 3mdzA-5kjaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 484
HIS A 183
HIS A 304
 FE2  A 502 (-4.0A)
FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
 0.54A 3qpkA-5kjaA:
undetectable		 3qpkA-5kjaA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 484
HIS A 183
HIS A 304
 FE2  A 502 (-4.0A)
FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
 0.54A 3qpkB-5kjaA:
undetectable		 3qpkB-5kjaA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		4 / 7 ILE A 133
LYS A  66
PHE A 113
GLY A 269
 None
 1.08A 3sj0X-5kjaA:
undetectable		 3sj0X-5kjaA:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_B_AZMB303_1
(CARBONIC ANHYDRASE 1)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		5 / 9 HIS A 304
HIS A 238
GLU A 150
HIS A 183
THR A 136
 FE2  A 502 (-3.8A)
FE2  A 502 (-4.5A)
None
FE2  A 502 (-4.0A)
None
 1.34A 3w6hB-5kjaA:
undetectable		 3w6hB-5kjaA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 304
GLU A 426
ASN A 137
 FE2  A 502 (-3.8A)
None
None
 0.90A 4bupB-5kjaA:
undetectable		 4bupB-5kjaA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		4 / 7 ASP A 239
ASN A 137
GLU A 426
GLU A 150
 None
 1.16A 4feuB-5kjaA:
undetectable		 4feuB-5kjaA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 LEU A 460
LEU A 443
LEU A  50
ILE A  42
VAL A  86
 None
 1.14A 4ok1A-5kjaA:
undetectable		 4ok1A-5kjaA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 PRO A 326
LEU A 325
HIS A 238
 None
None
FE2  A 502 (-4.5A)
 0.68A 4pevA-5kjaA:
undetectable		 4pevA-5kjaA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		4 / 6 GLU A 370
TYR A 322
LEU A 325
PHE A 303
 None
 1.35A 4twdF-5kjaA:
undetectable
4twdG-5kjaA:
undetectable		 4twdF-5kjaA:
20.24
4twdG-5kjaA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		5 / 11 HIS A 304
HIS A 238
GLU A 150
HIS A 183
THR A 136
 FE2  A 502 (-3.8A)
FE2  A 502 (-4.5A)
None
FE2  A 502 (-4.0A)
None
 1.43A 4ygfB-5kjaA:
undetectable		 4ygfB-5kjaA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H4D_A_BBIA403_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		4 / 6 PHE A 303
GLU A 150
PHE A 236
VAL A 112
 None
 1.32A 5h4dA-5kjaA:
undetectable		 5h4dA-5kjaA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		5 / 10 HIS A 304
HIS A 238
GLU A 150
HIS A 183
THR A 136
 FE2  A 502 (-3.8A)
FE2  A 502 (-4.5A)
None
FE2  A 502 (-4.0A)
None
 1.36A 5jn8D-5kjaA:
undetectable		 5jn8D-5kjaA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLU A 370
LEU A 250
ALA A 280
PHE A 301
ASN A 252
 None
 1.28A 5kc4E-5kjaA:
undetectable		 5kc4E-5kjaA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS A 484
HIS A 238
HIS A 183
HIS A 304
 FE2  A 502 (-4.0A)
FE2  A 502 (-4.5A)
FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
 0.83A 5mhwA-5kjaA:
undetectable		 5mhwA-5kjaA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS A 484
HIS A 238
HIS A 183
HIS A 304
 FE2  A 502 (-4.0A)
FE2  A 502 (-4.5A)
FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
 0.82A 5mhxA-5kjaA:
undetectable		 5mhxA-5kjaA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS A 484
HIS A 238
HIS A 183
HIS A 304
 FE2  A 502 (-4.0A)
FE2  A 502 (-4.5A)
FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
 0.83A 5mhyA-5kjaA:
undetectable		 5mhyA-5kjaA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS A 484
HIS A 238
HIS A 183
HIS A 304
 FE2  A 502 (-4.0A)
FE2  A 502 (-4.5A)
FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
 0.83A 5mhzA-5kjaA:
undetectable		 5mhzA-5kjaA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS A 484
HIS A 238
HIS A 183
HIS A 304
 FE2  A 502 (-4.0A)
FE2  A 502 (-4.5A)
FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
 0.83A 5mi1A-5kjaA:
undetectable		 5mi1A-5kjaA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS A 484
HIS A 238
HIS A 183
HIS A 304
 FE2  A 502 (-4.0A)
FE2  A 502 (-4.5A)
FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
 0.83A 5mi2A-5kjaA:
undetectable		 5mi2A-5kjaA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS A 484
HIS A 238
HIS A 183
HIS A 304
 FE2  A 502 (-4.0A)
FE2  A 502 (-4.5A)
FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
 0.84A 5miaA-5kjaA:
undetectable		 5miaA-5kjaA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS A 484
HIS A 238
HIS A 183
HIS A 304
 FE2  A 502 (-4.0A)
FE2  A 502 (-4.5A)
FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
 0.83A 5mibA-5kjaA:
undetectable		 5mibA-5kjaA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS A 484
HIS A 238
HIS A 183
HIS A 304
 FE2  A 502 (-4.0A)
FE2  A 502 (-4.5A)
FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
 0.83A 5micA-5kjaA:
undetectable		 5micA-5kjaA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS A 484
HIS A 238
HIS A 183
HIS A 304
 FE2  A 502 (-4.0A)
FE2  A 502 (-4.5A)
FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
 0.83A 5midA-5kjaA:
undetectable		 5midA-5kjaA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS A 484
HIS A 238
HIS A 183
HIS A 304
 FE2  A 502 (-4.0A)
FE2  A 502 (-4.5A)
FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
 0.83A 5mieA-5kjaA:
undetectable		 5mieA-5kjaA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 484
HIS A 183
HIS A 304
 FE2  A 502 (-4.0A)
FE2  A 502 (-4.0A)
FE2  A 502 (-3.8A)
 0.55A 5migA-5kjaA:
undetectable		 5migA-5kjaA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 304
GLU A 426
ASN A 137
 FE2  A 502 (-3.8A)
None
None
 0.90A 5wbvA-5kjaA:
undetectable		 5wbvA-5kjaA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 304
GLU A 426
ASN A 137
 FE2  A 502 (-3.8A)
None
None
 0.90A 5wbvB-5kjaA:
undetectable		 5wbvB-5kjaA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		4 / 5 HIS A 183
HIS A 238
PHE A 303
HIS A 304
 FE2  A 502 (-4.0A)
FE2  A 502 (-4.5A)
None
FE2  A 502 (-3.8A)
 1.08A 5zrdB-5kjaA:
undetectable		 5zrdB-5kjaA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 5kja APOCAROTENOID-15,15'
-OXYGENASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 ARG A 110
ARG A 129
ASP A 127
 None
 0.87A 6d8pA-5kjaA:
undetectable		 6d8pA-5kjaA:
21.84