SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kju'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		3 / 3 GLU A 346
ASN A  26
TRP A  23
 None
 1.11A 1r15C-5kjuA:
undetectable		 1r15C-5kjuA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		3 / 3 GLU A 346
ASN A  26
TRP A  23
 None
 1.18A 1r15D-5kjuA:
undetectable		 1r15D-5kjuA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		3 / 3 GLU A 346
ASN A  26
TRP A  23
 None
 1.15A 1r15E-5kjuA:
undetectable		 1r15E-5kjuA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		5 / 6 LEU A 147
TYR A  42
TYR A  40
ILE A 165
GLY A 384
 None
 1.49A 2du8B-5kjuA:
undetectable		 2du8B-5kjuA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		5 / 12 LEU A 418
VAL A 414
LEU A 257
HIS A 260
LEU A 430
 None
 1.36A 2hc4A-5kjuA:
undetectable		 2hc4A-5kjuA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_A_CAMA423_0
(CYTOCHROME P450)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		5 / 10 LEU A 279
LEU A 366
GLY A 367
VAL A 402
VAL A 414
 None
 1.26A 3lxiA-5kjuA:
undetectable		 3lxiA-5kjuA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_B_CAMB423_0
(CYTOCHROME P450)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		5 / 11 LEU A 279
LEU A 366
GLY A 367
VAL A 402
VAL A 414
 None
 1.25A 3lxiB-5kjuA:
undetectable		 3lxiB-5kjuA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_D_URFD400_1
(URIDINE
PHOSPHORYLASE 1)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		5 / 9 THR A 223
GLY A 398
MET A 423
LEU A 399
ILE A 394
 None
None
None
6TO  A 800 (-4.0A)
None
 1.48A 3nbqD-5kjuA:
undetectable		 3nbqD-5kjuA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6G_A_IZPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		5 / 12 VAL A  91
PRO A 181
ILE A  84
ARG A 185
CYH A  86
 None
 1.30A 3p6gA-5kjuA:
undetectable		 3p6gA-5kjuA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		5 / 11 PHE A 388
VAL A  39
PHE A  41
GLY A 393
LEU A 117
 None
 1.16A 3t3rA-5kjuA:
undetectable		 3t3rA-5kjuA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		4 / 5 ILE A 394
PRO A 395
SER A  38
GLY A 393
 None
None
6TO  A 800 ( 4.3A)
None
 0.88A 3tkdB-5kjuA:
undetectable		 3tkdB-5kjuA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		4 / 5 ILE A 394
PRO A 395
SER A  38
GLY A 393
 None
None
6TO  A 800 ( 4.3A)
None
 0.90A 3tkdA-5kjuA:
undetectable		 3tkdA-5kjuA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		5 / 9 LEU A 279
LEU A 366
GLY A 367
VAL A 402
VAL A 414
 None
 1.21A 4c9kB-5kjuA:
undetectable		 4c9kB-5kjuA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		5 / 10 LEU A 279
LEU A 366
GLY A 367
VAL A 402
VAL A 414
 None
 1.21A 4c9nB-5kjuA:
undetectable		 4c9nB-5kjuA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		5 / 9 LEU A 279
LEU A 366
GLY A 367
VAL A 402
VAL A 414
 None
 1.25A 4c9pA-5kjuA:
undetectable		 4c9pA-5kjuA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		5 / 10 LEU A 279
LEU A 366
GLY A 367
VAL A 402
VAL A 414
 None
 1.25A 4c9pB-5kjuA:
undetectable		 4c9pB-5kjuA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		4 / 6 GLU A  83
ILE A  84
ASN A  24
HIS A  35
 None
 1.10A 4ejwB-5kjuA:
undetectable		 4ejwB-5kjuA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		5 / 12 PHE A  93
ALA A  59
LEU A  60
VAL A 137
LEU A 135
 None
 0.73A 4g1bA-5kjuA:
undetectable		 4g1bA-5kjuA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		5 / 12 LEU A  64
PHE A 164
ALA A 155
MET A 151
GLY A 150
 None
None
None
6TO  A 800 (-3.9A)
None
 1.50A 4j7xA-5kjuA:
undetectable		 4j7xA-5kjuA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		5 / 12 ILE A 302
VAL A 301
GLY A 158
HIS A  35
CYH A  86
 6TO  A 800 (-4.2A)
None
6TO  A 800 (-3.5A)
None
None
 1.14A 5ergB-5kjuA:
undetectable		 5ergB-5kjuA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		3 / 3 ARG A 269
PHE A 429
LEU A 366
 None
 0.89A 5x1bC-5kjuA:
undetectable		 5x1bC-5kjuA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA503_1
(CYTOCHROME P450 2C9)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		4 / 5 PRO A 220
GLY A 219
ASN A 222
LYS A 217
 None
 1.02A 5x23A-5kjuA:
undetectable		 5x23A-5kjuA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJS_A_SALA603_0
(VICILIN-LIKE
ANTIMICROBIAL
PEPTIDES 2-2)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		5 / 11 GLY A  88
VAL A  91
PHE A 164
MET A  70
GLY A  90
 None
 1.16A 5yjsA-5kjuA:
undetectable		 5yjsA-5kjuA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_D_EY4D500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		4 / 7 ILE A   5
GLN A 136
VAL A  95
PRO A 119
 None
 0.94A 6cduC-5kjuA:
undetectable
6cduD-5kjuA:
undetectable		 6cduC-5kjuA:
21.95
6cduD-5kjuA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		4 / 8 ILE A   5
GLN A 136
VAL A  95
PRO A 119
 None
 1.01A 6cduG-5kjuA:
undetectable
6cduH-5kjuA:
undetectable		 6cduG-5kjuA:
21.95
6cduH-5kjuA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA416_0
(AROMATIC
PEROXYGENASE)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		4 / 4 LYS A 278
VAL A 355
ARG A 356
TYR A 280
 None
None
6TO  A 800 (-3.9A)
None
 1.47A 6ekzA-5kjuA:
0.0		 6ekzA-5kjuA:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_B_REAB601_1
(RETINOIC ACID
RECEPTOR)		 5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE
(Arabidopsis
thaliana) 		5 / 10 VAL A 414
SER A 400
LEU A 279
GLY A 259
VAL A 261
 None
 1.13A 6eu9B-5kjuA:
undetectable		 6eu9B-5kjuA:
10.16