SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kjv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J3J_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5kjv HYDROXYCINNAMOYL
TRANSFERASE
(Plectranthus
scutellarioides) 		5 / 9 ALA A 276
ILE A 410
ILE A 362
TYR A 248
THR A 298
 None
 1.43A 1j3jB-5kjvA:
undetectable		 1j3jB-5kjvA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_0
(MODIFICATION
METHYLASE RSRI)		 5kjv HYDROXYCINNAMOYL
TRANSFERASE
(Plectranthus
scutellarioides) 		5 / 12 PRO A  32
PHE A  34
SER A  38
VAL A 149
ALA A 389
 None
 1.18A 1nw5A-5kjvA:
undetectable		 1nw5A-5kjvA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 5kjv HYDROXYCINNAMOYL
TRANSFERASE
(Plectranthus
scutellarioides) 		3 / 3 GLU A 340
ASN A  26
TRP A  23
 None
 1.14A 1r15C-5kjvA:
undetectable		 1r15C-5kjvA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 5kjv HYDROXYCINNAMOYL
TRANSFERASE
(Plectranthus
scutellarioides) 		3 / 3 GLU A 340
ASN A  26
TRP A  23
 None
 1.18A 1r15E-5kjvA:
undetectable		 1r15E-5kjvA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 5kjv HYDROXYCINNAMOYL
TRANSFERASE
(Plectranthus
scutellarioides) 		3 / 3 TRP A 314
VAL A 313
PRO A 312
 None
 0.85A 1rg1A-5kjvA:
undetectable		 1rg1A-5kjvA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 5kjv HYDROXYCINNAMOYL
TRANSFERASE
(Plectranthus
scutellarioides) 		3 / 3 TRP A 314
VAL A 313
PRO A 312
 None
 0.85A 1rh0A-5kjvA:
undetectable		 1rh0A-5kjvA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)		 5kjv HYDROXYCINNAMOYL
TRANSFERASE
(Plectranthus
scutellarioides) 		4 / 8 PHE A 395
SER A 394
LEU A 393
THR A 363
 None
 0.87A 1sbrA-5kjvA:
undetectable		 1sbrA-5kjvA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BLA_A_CP6A302_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5kjv HYDROXYCINNAMOYL
TRANSFERASE
(Plectranthus
scutellarioides) 		5 / 11 ALA A 276
ILE A 410
ILE A 362
TYR A 248
THR A 298
 None
 1.27A 2blaA-5kjvA:
undetectable		 2blaA-5kjvA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_A_PXLA1003_1
(PYRIDOXINE KINASE)		 5kjv HYDROXYCINNAMOYL
TRANSFERASE
(Plectranthus
scutellarioides) 		4 / 8 VAL A 295
LEU A 187
PRO A 288
ASP A 157
 None
 0.91A 2ddwA-5kjvA:
undetectable		 2ddwA-5kjvA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 5kjv HYDROXYCINNAMOYL
TRANSFERASE
(Plectranthus
scutellarioides) 		5 / 6 LEU A 147
TYR A  42
TYR A  40
ILE A 165
GLY A 378
 None
 1.49A 2du8A-5kjvA:
undetectable		 2du8A-5kjvA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 5kjv HYDROXYCINNAMOYL
TRANSFERASE
(Plectranthus
scutellarioides) 		5 / 6 LEU A 147
TYR A  42
TYR A  40
ILE A 165
GLY A 378
 None
 1.45A 2du8B-5kjvA:
undetectable		 2du8B-5kjvA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID6_C_SAMC301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 5kjv HYDROXYCINNAMOYL
TRANSFERASE
(Plectranthus
scutellarioides) 		5 / 12 GLY A  72
ALA A  88
ALA A 155
ASP A  85
ILE A  84
 None
 1.10A 3id6C-5kjvA:
undetectable		 3id6C-5kjvA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_D_URFD400_1
(URIDINE
PHOSPHORYLASE 1)		 5kjv HYDROXYCINNAMOYL
TRANSFERASE
(Plectranthus
scutellarioides) 		5 / 9 THR A 217
GLY A 392
MET A 417
LEU A 393
ILE A 388
 None
 1.46A 3nbqD-5kjvA:
undetectable		 3nbqD-5kjvA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)		 5kjv HYDROXYCINNAMOYL
TRANSFERASE
(Plectranthus
scutellarioides) 		5 / 11 PHE A 382
VAL A  39
PHE A  41
GLY A 387
LEU A 117
 None
 1.11A 3t3rA-5kjvA:
undetectable		 3t3rA-5kjvA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)		 5kjv HYDROXYCINNAMOYL
TRANSFERASE
(Plectranthus
scutellarioides) 		4 / 7 LEU A 114
ARG A 116
GLY A 106
TYR A 105
 None
 0.90A 4cp3A-5kjvA:
undetectable
4cp3B-5kjvA:
undetectable		 4cp3A-5kjvA:
16.10
4cp3B-5kjvA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_A_TCWA1126_1
(TRANSTHYRETIN)		 5kjv HYDROXYCINNAMOYL
TRANSFERASE
(Plectranthus
scutellarioides) 		4 / 6 LEU A  60
ALA A  63
SER A 169
THR A 167
 None
 1.26A 4d7bB-5kjvA:
undetectable		 4d7bB-5kjvA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 5kjv HYDROXYCINNAMOYL
TRANSFERASE
(Plectranthus
scutellarioides) 		5 / 12 PHE A  93
ALA A  58
LEU A  60
VAL A 137
LEU A 135
 None
 1.03A 4g1bA-5kjvA:
undetectable		 4g1bA-5kjvA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 5kjv HYDROXYCINNAMOYL
TRANSFERASE
(Plectranthus
scutellarioides) 		5 / 12 PHE A  93
ALA A  59
LEU A  60
VAL A 137
LEU A 135
 None
 0.75A 4g1bA-5kjvA:
undetectable		 4g1bA-5kjvA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_B_REAB601_1
(RETINOIC ACID
RECEPTOR)		 5kjv HYDROXYCINNAMOYL
TRANSFERASE
(Plectranthus
scutellarioides) 		5 / 10 VAL A 408
SER A 394
LEU A 273
GLY A 253
VAL A 255
 None
 1.18A 6eu9B-5kjvA:
undetectable		 6eu9B-5kjvA:
11.94