SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kkx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDW_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 5kkx TBPB
(Neisseria
meningitidis) 		5 / 10 VAL A 512
LEU A 587
TYR A 580
PHE A 514
GLU A 585
 None
 1.50A 1fdwA-5kkxA:
undetectable		 1fdwA-5kkxA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 5kkx TBPB
(Neisseria
meningitidis) 		4 / 6 PHE A 605
TYR A 580
GLY A 577
LYS A 576
 None
 1.22A 2i30A-5kkxA:
undetectable		 2i30A-5kkxA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXZ_A_ADNA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 5kkx TBPB
(Neisseria
meningitidis) 		5 / 12 LEU A 587
GLY A 465
ILE A 519
GLY A 589
GLY A 588
 None
 1.08A 3axzA-5kkxA:
undetectable		 3axzA-5kkxA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_1
(PHOSPHOLIPASE A2)		 5kkx TBPB
(Neisseria
meningitidis) 		4 / 8 VAL A 480
LYS A 608
ARG A 482
LYS A 522
 None
 0.86A 3bjwA-5kkxA:
undetectable		 3bjwA-5kkxA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 5kkx TBPB
(Neisseria
meningitidis) 		4 / 7 PHE A 605
ALA A 499
GLY A 487
THR A 421
 None
 0.69A 5ybbB-5kkxA:
undetectable		 5ybbB-5kkxA:
18.62