SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kl0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)		 5kl0 PHOSPHOGLUCOMUTASE
(Xanthomonas
citri) 		4 / 6 PHE A 103
ILE A 204
LYS A 171
ALA A 173
 None
 1.22A 1hk2A-5kl0A:
undetectable		 1hk2A-5kl0A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5kl0 PHOSPHOGLUCOMUTASE
(Xanthomonas
citri) 		5 / 12 TYR A 339
THR A 307
ALA A 287
GLY A 277
HIS A 347
 None
 0.99A 1nbiC-5kl0A:
undetectable		 1nbiC-5kl0A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5kl0 PHOSPHOGLUCOMUTASE
(Xanthomonas
citri) 		5 / 12 TYR A 339
THR A 307
ALA A 287
GLY A 277
HIS A 347
 None
 1.01A 1nbiD-5kl0A:
undetectable		 1nbiD-5kl0A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)		 5kl0 PHOSPHOGLUCOMUTASE
(Xanthomonas
citri) 		5 / 12 GLY A 260
GLY A 197
ILE A 231
GLU A  99
ALA A 257
 SEP  A 119 ( 4.8A)
None
None
None
None
 1.01A 1nv8B-5kl0A:
undetectable		 1nv8B-5kl0A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_2
(CES1 PROTEIN)		 5kl0 PHOSPHOGLUCOMUTASE
(Xanthomonas
citri) 		4 / 4 LEU A 444
PRO A 301
ILE A 424
LEU A 435
 None
 1.10A 1ya4B-5kl0A:
1.2		 1ya4B-5kl0A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 5kl0 PHOSPHOGLUCOMUTASE
(Xanthomonas
citri) 		4 / 7 ILE A 393
GLY A 391
ARG A 302
LEU A 303
 None
None
G16  A 501 ( 3.6A)
None
 0.93A 3bjwH-5kl0A:
undetectable		 3bjwH-5kl0A:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 5kl0 PHOSPHOGLUCOMUTASE
(Xanthomonas
citri) 		3 / 3 TYR A 102
GLU A 342
ASP A 422
 None
G16  A 501 (-2.8A)
None
 0.78A 3bxoA-5kl0A:
undetectable		 3bxoA-5kl0A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_4
(HIV-1 PROTEASE)		 5kl0 PHOSPHOGLUCOMUTASE
(Xanthomonas
citri) 		4 / 4 LEU A 435
ASP A 427
VAL A 448
THR A 461
 None
 1.32A 3cyxB-5kl0A:
undetectable		 3cyxB-5kl0A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_A_ICFA1_1
(INTEGRIN ALPHA-L)		 5kl0 PHOSPHOGLUCOMUTASE
(Xanthomonas
citri) 		5 / 9 ILE A 288
LYS A 291
LEU A 364
GLU A 367
LEU A 368
 None
 1.48A 3f78A-5kl0A:
undetectable		 3f78A-5kl0A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 5kl0 PHOSPHOGLUCOMUTASE
(Xanthomonas
citri) 		5 / 12 LEU A 280
GLY A 282
GLN A 310
VAL A 311
ILE A 288
 None
 1.20A 3h52A-5kl0A:
undetectable		 3h52A-5kl0A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5kl0 PHOSPHOGLUCOMUTASE
(Xanthomonas
citri) 		5 / 12 HIS A 325
VAL A 114
LEU A 130
SER A 139
GLY A 127
 G16  A 501 (-4.0A)
None
None
None
None
 1.19A 3kk6B-5kl0A:
undetectable		 3kk6B-5kl0A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA1_1
(CYTOCHROME P450 2D6)		 5kl0 PHOSPHOGLUCOMUTASE
(Xanthomonas
citri) 		5 / 12 LEU A 192
PHE A 216
LEU A 208
LEU A 364
PHE A 267
 None
 1.30A 3tbgA-5kl0A:
undetectable		 3tbgA-5kl0A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA1_1
(CYTOCHROME P450 2D6)		 5kl0 PHOSPHOGLUCOMUTASE
(Xanthomonas
citri) 		5 / 12 LEU A 192
PHE A 216
LEU A 212
LEU A 364
PHE A 267
 None
 1.34A 3tbgA-5kl0A:
undetectable		 3tbgA-5kl0A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 5kl0 PHOSPHOGLUCOMUTASE
(Xanthomonas
citri) 		5 / 12 LEU A 192
PHE A 216
LEU A 208
LEU A 364
PHE A 267
 None
 1.32A 3tbgC-5kl0A:
undetectable		 3tbgC-5kl0A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 5kl0 PHOSPHOGLUCOMUTASE
(Xanthomonas
citri) 		5 / 12 LEU A 192
PHE A 216
LEU A 212
LEU A 364
PHE A 267
 None
 1.33A 3tbgC-5kl0A:
undetectable		 3tbgC-5kl0A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5kl0 PHOSPHOGLUCOMUTASE
(Xanthomonas
citri) 		5 / 12 SER A 357
ILE A 360
TYR A 181
LEU A 363
HIS A 177
 None
 1.32A 3vn2A-5kl0A:
undetectable		 3vn2A-5kl0A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5kl0 PHOSPHOGLUCOMUTASE
(Xanthomonas
citri) 		4 / 8 GLY A 358
HIS A 347
PHE A 267
PHE A 254
 None
 0.93A 4fglD-5kl0A:
undetectable		 4fglD-5kl0A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_F_BEZF501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 5kl0 PHOSPHOGLUCOMUTASE
(Xanthomonas
citri) 		4 / 8 ASN A 447
SER A 390
LEU A 303
TYR A 279
 None
 1.18A 4ijiF-5kl0A:
undetectable		 4ijiF-5kl0A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_0
(PROLINE--TRNA LIGASE)		 5kl0 PHOSPHOGLUCOMUTASE
(Xanthomonas
citri) 		5 / 12 GLU A 312
VAL A 311
THR A 304
GLU A 449
SER A 425
 None
 1.20A 4q15B-5kl0A:
4.7		 4q15B-5kl0A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_0
(PROLINE--TRNA LIGASE)		 5kl0 PHOSPHOGLUCOMUTASE
(Xanthomonas
citri) 		5 / 12 GLU A 312
VAL A 311
THR A 304
GLU A 449
SER A 425
 None
 1.33A 4ydqB-5kl0A:
5.1		 4ydqB-5kl0A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 5kl0 PHOSPHOGLUCOMUTASE
(Xanthomonas
citri) 		5 / 12 LEU A 280
GLY A 282
GLN A 310
VAL A 311
LEU A 364
 None
 1.39A 5uc3B-5kl0A:
undetectable		 5uc3B-5kl0A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5kl0 PHOSPHOGLUCOMUTASE
(Xanthomonas
citri) 		4 / 5 PHE A 267
PHE A 254
LEU A 192
PHE A 216
 None
 1.34A 5xdqP-5kl0A:
undetectable
5xdqW-5kl0A:
undetectable		 5xdqP-5kl0A:
18.99
5xdqW-5kl0A:
11.23