SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5klf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5klf CARBOHYDRATE BINDING
MODULE E1
(uncultured
bacterium) 		5 / 10 ALA A  25
PHE A  90
ALA A  17
LEU A  40
VAL A  71
 None
 1.12A 1claA-5klfA:
undetectable		 1claA-5klfA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 5klf CARBOHYDRATE BINDING
MODULE E1
(uncultured
bacterium) 		4 / 6 ILE A  42
ASN A  63
SER A  50
THR A  46
 None
 1.16A 1h7xA-5klfA:
undetectable		 1h7xA-5klfA:
6.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 5klf CARBOHYDRATE BINDING
MODULE E1
(uncultured
bacterium) 		4 / 6 ILE A  42
ASN A  63
SER A  50
THR A  46
 None
 1.16A 1h7xB-5klfA:
undetectable		 1h7xB-5klfA:
6.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 5klf CARBOHYDRATE BINDING
MODULE E1
(uncultured
bacterium) 		4 / 6 ILE A  42
ASN A  63
SER A  50
THR A  46
 None
 1.15A 1h7xC-5klfA:
undetectable		 1h7xC-5klfA:
6.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 5klf CARBOHYDRATE BINDING
MODULE E1
(uncultured
bacterium) 		4 / 6 ILE A  42
ASN A  63
SER A  50
THR A  46
 None
 1.14A 1h7xD-5klfA:
undetectable		 1h7xD-5klfA:
6.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5klf CARBOHYDRATE BINDING
MODULE E1
(uncultured
bacterium) 		4 / 7 TYR A  52
GLU A  22
THR A  46
SER A  44
 None
GD  A 111 ( 3.1A)
None
None
 1.22A 1tv8A-5klfA:
undetectable		 1tv8A-5klfA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC1383_1
(CES1 PROTEIN)		 5klf CARBOHYDRATE BINDING
MODULE E1
(uncultured
bacterium) 		4 / 5 PRO A  58
LEU A  79
GLY A  77
LYS A  35
 None
 1.38A 1ya4C-5klfA:
undetectable		 1ya4C-5klfA:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 5klf CARBOHYDRATE BINDING
MODULE E1
(uncultured
bacterium) 		4 / 8 ILE A  31
ALA A  25
PHE A  90
ALA A  86
 None
 0.76A 3hrdA-5klfA:
undetectable
3hrdB-5klfA:
undetectable		 3hrdA-5klfA:
13.77
3hrdB-5klfA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5klf CARBOHYDRATE BINDING
MODULE E1
(uncultured
bacterium) 		3 / 3 LYS A  19
ASN A  96
SER A  36
 GD  A 109 ( 4.7A)
None
None
 1.28A 5yw0A-5klfA:
undetectable		 5yw0A-5klfA:
15.05