SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5klp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 5klp ORF34
(Pseudomonas
syringae) 		5 / 12 ILE A 122
VAL A 197
LEU A 199
ALA A 154
ILE A 168
 None
 1.02A 1epbA-5klpA:
undetectable		 1epbA-5klpA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 5klp ORF34
(Pseudomonas
syringae) 		5 / 12 ILE A 122
VAL A 197
LEU A 199
ALA A 154
ILE A 168
 None
 1.01A 1epbB-5klpA:
undetectable		 1epbB-5klpA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5klp ORF34
(Pseudomonas
syringae) 		4 / 7 PHE A 287
ALA A 227
ILE A 205
ILE A 237
 None
 0.87A 1oniD-5klpA:
undetectable
1oniF-5klpA:
undetectable		 1oniD-5klpA:
16.71
1oniF-5klpA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_B_FK5B401_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 5klp ORF34
(Pseudomonas
syringae) 		5 / 10 LEU A 112
VAL A 156
ILE A 166
ILE A 204
PHE A 137
 None
 1.40A 1q6iB-5klpA:
undetectable		 1q6iB-5klpA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2001_1
(SERUM ALBUMIN)		 5klp ORF34
(Pseudomonas
syringae) 		4 / 8 ALA A 203
ALA A 154
ARG A 134
LEU A 121
 None
 0.82A 2bxmA-5klpA:
undetectable		 2bxmA-5klpA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_2
(ESTROGEN RECEPTOR)		 5klp ORF34
(Pseudomonas
syringae) 		4 / 4 LEU A 246
THR A 245
ILE A 166
HIS A 238
 None
 1.31A 2jfaB-5klpA:
undetectable		 2jfaB-5klpA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA91_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5klp ORF34
(Pseudomonas
syringae) 		3 / 3 PHE A 115
GLN A 139
PHE A 133
 None
 0.75A 3rv5A-5klpA:
0.6		 3rv5A-5klpA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 5klp ORF34
(Pseudomonas
syringae) 		5 / 11 ASP A  77
GLN A  73
ALA A  70
VAL A  61
ILE A  54
 None
 1.38A 4uuuA-5klpA:
undetectable
4uuuB-5klpA:
undetectable		 4uuuA-5klpA:
19.20
4uuuB-5klpA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 5klp ORF34
(Pseudomonas
syringae) 		4 / 8 LEU A 182
GLU A 206
HIS A 271
LEU A 189
 None
 1.16A 5dxeA-5klpA:
undetectable		 5dxeA-5klpA:
20.50