SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kn8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.32A 1k2rA-5kn8A:
undetectable
1k2rB-5kn8A:
undetectable		 1k2rA-5kn8A:
22.08
1k2rB-5kn8A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 1k2rA-5kn8A:
undetectable
1k2rB-5kn8A:
undetectable		 1k2rA-5kn8A:
22.08
1k2rB-5kn8A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 1k2sA-5kn8A:
undetectable
1k2sB-5kn8A:
undetectable		 1k2sA-5kn8A:
22.08
1k2sB-5kn8A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 1k2sA-5kn8A:
undetectable
1k2sB-5kn8A:
undetectable		 1k2sA-5kn8A:
22.08
1k2sB-5kn8A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.29A 1k2tA-5kn8A:
2.0
1k2tB-5kn8A:
undetectable		 1k2tA-5kn8A:
22.08
1k2tB-5kn8A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 1k2uA-5kn8A:
undetectable
1k2uB-5kn8A:
undetectable		 1k2uA-5kn8A:
22.08
1k2uB-5kn8A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.32A 1m00A-5kn8A:
undetectable
1m00B-5kn8A:
undetectable		 1m00A-5kn8A:
22.08
1m00B-5kn8A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.31A 1mmvA-5kn8A:
undetectable
1mmvB-5kn8A:
undetectable		 1mmvA-5kn8A:
22.08
1mmvB-5kn8A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.30A 1mmwA-5kn8A:
undetectable
1mmwB-5kn8A:
undetectable		 1mmwA-5kn8A:
22.08
1mmwB-5kn8A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 5 LEU A  17
VAL A 210
CYH A 214
ALA A 216
 None
None
SF4  A 301 (-2.3A)
SF4  A 301 ( 4.8A)
 1.00A 1mz9D-5kn8A:
undetectable		 1mz9D-5kn8A:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 1om4A-5kn8A:
undetectable
1om4B-5kn8A:
undetectable		 1om4A-5kn8A:
22.28
1om4B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 8 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.29A 1om5A-5kn8A:
undetectable
1om5B-5kn8A:
undetectable		 1om5A-5kn8A:
22.08
1om5B-5kn8A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.28A 1om5A-5kn8A:
undetectable
1om5B-5kn8A:
undetectable		 1om5A-5kn8A:
22.08
1om5B-5kn8A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.37A 1p6iA-5kn8A:
undetectable
1p6iB-5kn8A:
undetectable		 1p6iA-5kn8A:
22.08
1p6iB-5kn8A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 1p6iA-5kn8A:
undetectable
1p6iB-5kn8A:
undetectable		 1p6iA-5kn8A:
22.08
1p6iB-5kn8A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 8 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.31A 1rs6A-5kn8A:
undetectable
1rs6B-5kn8A:
undetectable		 1rs6A-5kn8A:
22.08
1rs6B-5kn8A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.31A 1rs7A-5kn8A:
undetectable
1rs7B-5kn8A:
undetectable		 1rs7A-5kn8A:
22.08
1rs7B-5kn8A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_A_H4BA900_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.35A 1zvlA-5kn8A:
undetectable
1zvlB-5kn8A:
undetectable		 1zvlA-5kn8A:
20.24
1zvlB-5kn8A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_B_H4BB920_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 1zvlA-5kn8A:
undetectable
1zvlB-5kn8A:
undetectable		 1zvlA-5kn8A:
20.24
1zvlB-5kn8A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 1zzqA-5kn8A:
undetectable
1zzqB-5kn8A:
undetectable		 1zzqA-5kn8A:
22.28
1zzqB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 2g6mA-5kn8A:
undetectable
2g6mB-5kn8A:
undetectable		 2g6mA-5kn8A:
22.28
2g6mB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 2hx3A-5kn8A:
undetectable
2hx3B-5kn8A:
undetectable		 2hx3A-5kn8A:
22.28
2hx3B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.31A 2hx4A-5kn8A:
undetectable
2hx4B-5kn8A:
undetectable		 2hx4A-5kn8A:
22.28
2hx4B-5kn8A:
22.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IZQ_C_DVAC8_0
(GRAMICIDIN D)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		3 / 3 VAL A  92
TRP A  40
VAL A  41
 None
 0.94A 2izqC-5kn8A:
undetectable
2izqD-5kn8A:
undetectable		 2izqC-5kn8A:
32.26
2izqD-5kn8A:
32.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 3b3mA-5kn8A:
undetectable
3b3mB-5kn8A:
undetectable		 3b3mA-5kn8A:
22.28
3b3mB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.32A 3b3oA-5kn8A:
undetectable
3b3oB-5kn8A:
undetectable		 3b3oA-5kn8A:
22.28
3b3oB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 3b3pA-5kn8A:
undetectable
3b3pB-5kn8A:
undetectable		 3b3pA-5kn8A:
22.28
3b3pB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 8 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.31A 3b3pA-5kn8A:
undetectable
3b3pB-5kn8A:
undetectable		 3b3pA-5kn8A:
22.28
3b3pB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 3dqrA-5kn8A:
undetectable
3dqrB-5kn8A:
undetectable		 3dqrA-5kn8A:
21.57
3dqrB-5kn8A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.28A 3jt3A-5kn8A:
undetectable
3jt3B-5kn8A:
undetectable		 3jt3A-5kn8A:
22.28
3jt3B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 3jt4A-5kn8A:
undetectable
3jt4B-5kn8A:
undetectable		 3jt4A-5kn8A:
22.28
3jt4B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 3jt6A-5kn8A:
undetectable
3jt6B-5kn8A:
undetectable		 3jt6A-5kn8A:
22.28
3jt6B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 3jt7A-5kn8A:
undetectable
3jt7B-5kn8A:
undetectable		 3jt7A-5kn8A:
22.28
3jt7B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.32A 3jt8A-5kn8A:
undetectable
3jt8B-5kn8A:
undetectable		 3jt8A-5kn8A:
22.28
3jt8B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 3jtaA-5kn8A:
undetectable
3jtaB-5kn8A:
undetectable		 3jtaA-5kn8A:
22.28
3jtaB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 3jwsA-5kn8A:
undetectable
3jwsB-5kn8A:
undetectable		 3jwsA-5kn8A:
22.02
3jwsB-5kn8A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.31A 3jwsA-5kn8A:
undetectable
3jwsB-5kn8A:
undetectable		 3jwsA-5kn8A:
22.02
3jwsB-5kn8A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 3jwtA-5kn8A:
undetectable
3jwtB-5kn8A:
undetectable		 3jwtA-5kn8A:
22.02
3jwtB-5kn8A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.32A 3jwuA-5kn8A:
undetectable
3jwuB-5kn8A:
undetectable		 3jwuA-5kn8A:
22.02
3jwuB-5kn8A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.30A 3jwvA-5kn8A:
undetectable
3jwvB-5kn8A:
undetectable		 3jwvA-5kn8A:
22.02
3jwvB-5kn8A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 3jwvA-5kn8A:
undetectable
3jwvB-5kn8A:
undetectable		 3jwvA-5kn8A:
22.02
3jwvB-5kn8A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 3jx0A-5kn8A:
undetectable
3jx0B-5kn8A:
undetectable		 3jx0A-5kn8A:
22.28
3jx0B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 3jx0A-5kn8A:
undetectable
3jx0B-5kn8A:
undetectable		 3jx0A-5kn8A:
22.28
3jx0B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 3jx1A-5kn8A:
undetectable
3jx1B-5kn8A:
undetectable		 3jx1A-5kn8A:
22.28
3jx1B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 3jx5A-5kn8A:
undetectable
3jx5B-5kn8A:
1.1		 3jx5A-5kn8A:
21.57
3jx5B-5kn8A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA300_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 PHE A   8
TYR A 213
VAL A 150
PHE A  13
 None
 1.27A 3ltwA-5kn8A:
undetectable		 3ltwA-5kn8A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 3n2rA-5kn8A:
undetectable
3n2rB-5kn8A:
undetectable		 3n2rA-5kn8A:
22.28
3n2rB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.29A 3n5vA-5kn8A:
undetectable
3n5vB-5kn8A:
undetectable		 3n5vA-5kn8A:
22.28
3n5vB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.32A 3n5yA-5kn8A:
undetectable
3n5yB-5kn8A:
undetectable		 3n5yA-5kn8A:
22.28
3n5yB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 3n5yA-5kn8A:
undetectable
3n5yB-5kn8A:
undetectable		 3n5yA-5kn8A:
22.28
3n5yB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.30A 3n5zA-5kn8A:
undetectable
3n5zB-5kn8A:
undetectable		 3n5zA-5kn8A:
22.28
3n5zB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 3n5zA-5kn8A:
undetectable
3n5zB-5kn8A:
undetectable		 3n5zA-5kn8A:
22.28
3n5zB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 3n61A-5kn8A:
undetectable
3n61B-5kn8A:
undetectable		 3n61A-5kn8A:
21.57
3n61B-5kn8A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.32A 3n65A-5kn8A:
1.0
3n65B-5kn8A:
undetectable		 3n65A-5kn8A:
22.28
3n65B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.29A 3nljA-5kn8A:
undetectable
3nljB-5kn8A:
undetectable		 3nljA-5kn8A:
21.57
3nljB-5kn8A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.36A 3nlmA-5kn8A:
undetectable
3nlmB-5kn8A:
undetectable		 3nlmA-5kn8A:
22.28
3nlmB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.31A 3nlnA-5kn8A:
undetectable
3nlnB-5kn8A:
undetectable		 3nlnA-5kn8A:
22.02
3nlnB-5kn8A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 3nloA-5kn8A:
undetectable
3nloB-5kn8A:
undetectable		 3nloA-5kn8A:
22.02
3nloB-5kn8A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 3nlvA-5kn8A:
undetectable
3nlvB-5kn8A:
undetectable		 3nlvA-5kn8A:
22.28
3nlvB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.32A 3nlwA-5kn8A:
undetectable
3nlwB-5kn8A:
undetectable		 3nlwA-5kn8A:
22.28
3nlwB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 3nlwA-5kn8A:
undetectable
3nlwB-5kn8A:
undetectable		 3nlwA-5kn8A:
22.28
3nlwB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.36A 3nlzA-5kn8A:
undetectable
3nlzB-5kn8A:
undetectable		 3nlzA-5kn8A:
22.28
3nlzB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 3nnzA-5kn8A:
undetectable
3nnzB-5kn8A:
undetectable		 3nnzA-5kn8A:
22.28
3nnzB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.35A 3q9aA-5kn8A:
undetectable
3q9aB-5kn8A:
undetectable		 3q9aA-5kn8A:
22.28
3q9aB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.35A 3rqjA-5kn8A:
undetectable
3rqjB-5kn8A:
undetectable		 3rqjA-5kn8A:
22.28
3rqjB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 3rqjA-5kn8A:
undetectable
3rqjB-5kn8A:
undetectable		 3rqjA-5kn8A:
22.28
3rqjB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 8 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 3rqlA-5kn8A:
undetectable
3rqlB-5kn8A:
undetectable		 3rqlA-5kn8A:
22.28
3rqlB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 3rqmA-5kn8A:
undetectable
3rqmB-5kn8A:
undetectable		 3rqmA-5kn8A:
22.28
3rqmB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 3rqnA-5kn8A:
undetectable
3rqnB-5kn8A:
undetectable		 3rqnA-5kn8A:
22.28
3rqnB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 3svqA-5kn8A:
undetectable
3svqB-5kn8A:
undetectable		 3svqA-5kn8A:
22.28
3svqB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 3tylA-5kn8A:
undetectable
3tylB-5kn8A:
undetectable		 3tylA-5kn8A:
22.28
3tylB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 3tylA-5kn8A:
undetectable
3tylB-5kn8A:
undetectable		 3tylA-5kn8A:
22.28
3tylB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.31A 3tymA-5kn8A:
undetectable
3tymB-5kn8A:
undetectable		 3tymA-5kn8A:
22.28
3tymB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 3tymA-5kn8A:
undetectable
3tymB-5kn8A:
undetectable		 3tymA-5kn8A:
22.28
3tymB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 3tynA-5kn8A:
undetectable
3tynB-5kn8A:
undetectable		 3tynA-5kn8A:
22.28
3tynB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 3tyoA-5kn8A:
undetectable
3tyoB-5kn8A:
undetectable		 3tyoA-5kn8A:
22.28
3tyoB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 3tyoA-5kn8A:
undetectable
3tyoB-5kn8A:
undetectable		 3tyoA-5kn8A:
22.28
3tyoB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.31A 3ufsA-5kn8A:
undetectable
3ufsB-5kn8A:
undetectable		 3ufsA-5kn8A:
22.28
3ufsB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 3ufuA-5kn8A:
undetectable
3ufuB-5kn8A:
undetectable		 3ufuA-5kn8A:
22.28
3ufuB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 3ufuA-5kn8A:
undetectable
3ufuB-5kn8A:
undetectable		 3ufuA-5kn8A:
22.28
3ufuB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 3ufvA-5kn8A:
undetectable
3ufvB-5kn8A:
undetectable		 3ufvA-5kn8A:
22.28
3ufvB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 3ufvA-5kn8A:
1.0
3ufvB-5kn8A:
undetectable		 3ufvA-5kn8A:
22.28
3ufvB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 3ufwA-5kn8A:
0.9
3ufwB-5kn8A:
undetectable		 3ufwA-5kn8A:
22.28
3ufwB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 4c39A-5kn8A:
undetectable
4c39B-5kn8A:
undetectable		 4c39A-5kn8A:
22.28
4c39B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 4camA-5kn8A:
undetectable
4camB-5kn8A:
undetectable		 4camA-5kn8A:
22.28
4camB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 4canA-5kn8A:
undetectable
4canB-5kn8A:
undetectable		 4canA-5kn8A:
22.28
4canB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 4caqA-5kn8A:
undetectable
4caqB-5kn8A:
1.1		 4caqA-5kn8A:
22.28
4caqB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.31A 4cdtA-5kn8A:
undetectable
4cdtB-5kn8A:
undetectable		 4cdtA-5kn8A:
22.28
4cdtB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.31A 4cdtA-5kn8A:
undetectable
4cdtB-5kn8A:
undetectable		 4cdtA-5kn8A:
22.28
4cdtB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 LEU A 120
ARG A 119
GLY A 107
TYR A 106
 None
 0.87A 4cp3A-5kn8A:
undetectable
4cp3B-5kn8A:
undetectable		 4cp3A-5kn8A:
21.93
4cp3B-5kn8A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 4ctpA-5kn8A:
undetectable
4ctpB-5kn8A:
undetectable		 4ctpA-5kn8A:
22.28
4ctpB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.32A 4ctqA-5kn8A:
0.9
4ctqB-5kn8A:
undetectable		 4ctqA-5kn8A:
22.28
4ctqB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 4ctrA-5kn8A:
undetectable
4ctrB-5kn8A:
undetectable		 4ctrA-5kn8A:
22.28
4ctrB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 4ctrA-5kn8A:
undetectable
4ctrB-5kn8A:
undetectable		 4ctrA-5kn8A:
22.28
4ctrB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 4cttA-5kn8A:
undetectable
4cttB-5kn8A:
undetectable		 4cttA-5kn8A:
22.28
4cttB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 4cttA-5kn8A:
undetectable
4cttB-5kn8A:
undetectable		 4cttA-5kn8A:
22.28
4cttB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.32A 4ctuA-5kn8A:
undetectable
4ctuB-5kn8A:
1.1		 4ctuA-5kn8A:
22.28
4ctuB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 4ctuA-5kn8A:
undetectable
4ctuB-5kn8A:
1.1		 4ctuA-5kn8A:
22.28
4ctuB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 4ctvA-5kn8A:
undetectable
4ctvB-5kn8A:
undetectable		 4ctvA-5kn8A:
22.28
4ctvB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 4ctwA-5kn8A:
undetectable
4ctwB-5kn8A:
undetectable		 4ctwA-5kn8A:
22.28
4ctwB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.35A 4cx5A-5kn8A:
undetectable
4cx5B-5kn8A:
undetectable		 4cx5A-5kn8A:
22.28
4cx5B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 4cx5A-5kn8A:
undetectable
4cx5B-5kn8A:
undetectable		 4cx5A-5kn8A:
22.28
4cx5B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 4cx6A-5kn8A:
undetectable
4cx6B-5kn8A:
undetectable		 4cx6A-5kn8A:
22.28
4cx6B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 4cx6A-5kn8A:
undetectable
4cx6B-5kn8A:
undetectable		 4cx6A-5kn8A:
22.28
4cx6B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 4d30A-5kn8A:
undetectable
4d30B-5kn8A:
undetectable		 4d30A-5kn8A:
22.28
4d30B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.31A 4d30A-5kn8A:
undetectable
4d30B-5kn8A:
undetectable		 4d30A-5kn8A:
22.28
4d30B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.32A 4d31A-5kn8A:
undetectable
4d31B-5kn8A:
undetectable		 4d31A-5kn8A:
22.28
4d31B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.30A 4d31A-5kn8A:
undetectable
4d31B-5kn8A:
undetectable		 4d31A-5kn8A:
22.28
4d31B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 4d32A-5kn8A:
undetectable
4d32B-5kn8A:
undetectable		 4d32A-5kn8A:
22.28
4d32B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 8 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 4d32A-5kn8A:
undetectable
4d32B-5kn8A:
undetectable		 4d32A-5kn8A:
22.28
4d32B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.35A 4d7oA-5kn8A:
undetectable
4d7oB-5kn8A:
undetectable		 4d7oA-5kn8A:
22.28
4d7oB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 4d7oA-5kn8A:
undetectable
4d7oB-5kn8A:
undetectable		 4d7oA-5kn8A:
22.28
4d7oB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.35A 4euxA-5kn8A:
undetectable
4euxB-5kn8A:
undetectable		 4euxA-5kn8A:
22.28
4euxB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 4fvwA-5kn8A:
undetectable
4fvwB-5kn8A:
undetectable		 4fvwA-5kn8A:
22.28
4fvwB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 4fvwA-5kn8A:
undetectable
4fvwB-5kn8A:
undetectable		 4fvwA-5kn8A:
22.28
4fvwB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 4fvxA-5kn8A:
undetectable
4fvxB-5kn8A:
undetectable		 4fvxA-5kn8A:
22.28
4fvxB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 4fvyA-5kn8A:
undetectable
4fvyB-5kn8A:
undetectable		 4fvyA-5kn8A:
22.28
4fvyB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.36A 4fvyA-5kn8A:
undetectable
4fvyB-5kn8A:
undetectable		 4fvyA-5kn8A:
22.28
4fvyB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 4fw0A-5kn8A:
undetectable
4fw0B-5kn8A:
undetectable		 4fw0A-5kn8A:
22.28
4fw0B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 4gqeA-5kn8A:
undetectable
4gqeB-5kn8A:
undetectable		 4gqeA-5kn8A:
22.28
4gqeB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 4imtA-5kn8A:
1.0
4imtB-5kn8A:
undetectable		 4imtA-5kn8A:
22.28
4imtB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 4imtA-5kn8A:
1.0
4imtB-5kn8A:
undetectable		 4imtA-5kn8A:
22.28
4imtB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 4imuA-5kn8A:
undetectable
4imuB-5kn8A:
undetectable		 4imuA-5kn8A:
22.28
4imuB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMU_A_H4BA809_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 4imuA-5kn8A:
undetectable
4imuB-5kn8A:
undetectable		 4imuA-5kn8A:
22.28
4imuB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_A_H4BA804_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.37A 4jseA-5kn8A:
undetectable
4jseB-5kn8A:
undetectable		 4jseA-5kn8A:
22.28
4jseB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.36A 4jseA-5kn8A:
undetectable
4jseB-5kn8A:
undetectable		 4jseA-5kn8A:
22.28
4jseB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 4jsfA-5kn8A:
undetectable
4jsfB-5kn8A:
undetectable		 4jsfA-5kn8A:
22.28
4jsfB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 4jsfA-5kn8A:
undetectable
4jsfB-5kn8A:
undetectable		 4jsfA-5kn8A:
22.28
4jsfB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.32A 4jsgA-5kn8A:
undetectable
4jsgB-5kn8A:
undetectable		 4jsgA-5kn8A:
22.28
4jsgB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 4jsgA-5kn8A:
undetectable
4jsgB-5kn8A:
undetectable		 4jsgA-5kn8A:
22.28
4jsgB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.28A 4jshA-5kn8A:
undetectable
4jshB-5kn8A:
undetectable		 4jshA-5kn8A:
22.28
4jshB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.30A 4jshA-5kn8A:
undetectable
4jshB-5kn8A:
undetectable		 4jshA-5kn8A:
22.28
4jshB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.31A 4jsiA-5kn8A:
undetectable
4jsiB-5kn8A:
undetectable		 4jsiA-5kn8A:
22.28
4jsiB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 4jsiA-5kn8A:
undetectable
4jsiB-5kn8A:
undetectable		 4jsiA-5kn8A:
22.28
4jsiB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.35A 4jsjA-5kn8A:
undetectable
4jsjB-5kn8A:
undetectable		 4jsjA-5kn8A:
22.28
4jsjB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 4jsjA-5kn8A:
undetectable
4jsjB-5kn8A:
undetectable		 4jsjA-5kn8A:
22.28
4jsjB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.31A 4k5dA-5kn8A:
undetectable
4k5dB-5kn8A:
undetectable		 4k5dA-5kn8A:
22.28
4k5dB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 4k5dA-5kn8A:
undetectable
4k5dB-5kn8A:
undetectable		 4k5dA-5kn8A:
22.28
4k5dB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 4k5eA-5kn8A:
undetectable
4k5eB-5kn8A:
undetectable		 4k5eA-5kn8A:
22.28
4k5eB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 4k5eA-5kn8A:
undetectable
4k5eB-5kn8A:
undetectable		 4k5eA-5kn8A:
22.28
4k5eB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 4k5fA-5kn8A:
undetectable
4k5fB-5kn8A:
undetectable		 4k5fA-5kn8A:
22.28
4k5fB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 4k5gA-5kn8A:
undetectable
4k5gB-5kn8A:
undetectable		 4k5gA-5kn8A:
22.28
4k5gB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 4k5gA-5kn8A:
undetectable
4k5gB-5kn8A:
undetectable		 4k5gA-5kn8A:
22.28
4k5gB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 4kcjA-5kn8A:
undetectable
4kcjB-5kn8A:
undetectable		 4kcjA-5kn8A:
22.28
4kcjB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 4kclA-5kn8A:
undetectable
4kclB-5kn8A:
undetectable		 4kclA-5kn8A:
22.28
4kclB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 4kcmA-5kn8A:
undetectable
4kcmB-5kn8A:
undetectable		 4kcmA-5kn8A:
22.28
4kcmB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 4kcnA-5kn8A:
undetectable
4kcnB-5kn8A:
undetectable		 4kcnA-5kn8A:
22.28
4kcnB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 4kcoA-5kn8A:
undetectable
4kcoB-5kn8A:
undetectable		 4kcoA-5kn8A:
22.28
4kcoB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.32A 4luxA-5kn8A:
undetectable
4luxB-5kn8A:
undetectable		 4luxA-5kn8A:
22.28
4luxB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 4luxA-5kn8A:
undetectable
4luxB-5kn8A:
undetectable		 4luxA-5kn8A:
22.28
4luxB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 8 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.36A 4uchA-5kn8A:
undetectable
4uchB-5kn8A:
undetectable		 4uchA-5kn8A:
21.41
4uchB-5kn8A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.35A 4ugzA-5kn8A:
undetectable
4ugzB-5kn8A:
undetectable		 4ugzA-5kn8A:
22.28
4ugzB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 4ugzA-5kn8A:
undetectable
4ugzB-5kn8A:
undetectable		 4ugzA-5kn8A:
22.28
4ugzB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 4uh0A-5kn8A:
undetectable
4uh0B-5kn8A:
1.1		 4uh0A-5kn8A:
22.28
4uh0B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.30A 4uh0A-5kn8A:
undetectable
4uh0B-5kn8A:
1.1		 4uh0A-5kn8A:
22.28
4uh0B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.32A 4uh1A-5kn8A:
undetectable
4uh1B-5kn8A:
undetectable		 4uh1A-5kn8A:
22.28
4uh1B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 4uh1A-5kn8A:
undetectable
4uh1B-5kn8A:
undetectable		 4uh1A-5kn8A:
22.28
4uh1B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.32A 4uh2A-5kn8A:
undetectable
4uh2B-5kn8A:
undetectable		 4uh2A-5kn8A:
22.28
4uh2B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 4uh2A-5kn8A:
undetectable
4uh2B-5kn8A:
undetectable		 4uh2A-5kn8A:
22.28
4uh2B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.37A 4uh3A-5kn8A:
undetectable
4uh3B-5kn8A:
undetectable		 4uh3A-5kn8A:
22.28
4uh3B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 4uh3A-5kn8A:
undetectable
4uh3B-5kn8A:
undetectable		 4uh3A-5kn8A:
22.28
4uh3B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 4uh4A-5kn8A:
undetectable
4uh4B-5kn8A:
undetectable		 4uh4A-5kn8A:
22.28
4uh4B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.32A 4uh5A-5kn8A:
undetectable
4uh5B-5kn8A:
undetectable		 4uh5A-5kn8A:
21.21
4uh5B-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 4uh5A-5kn8A:
undetectable
4uh5B-5kn8A:
undetectable		 4uh5A-5kn8A:
21.21
4uh5B-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.37A 4uh6A-5kn8A:
undetectable
4uh6B-5kn8A:
undetectable		 4uh6A-5kn8A:
21.21
4uh6B-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 4uh6A-5kn8A:
1.0
4uh6B-5kn8A:
undetectable		 4uh6A-5kn8A:
21.21
4uh6B-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 4upoA-5kn8A:
undetectable
4upoB-5kn8A:
undetectable		 4upoA-5kn8A:
22.28
4upoB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 4v3yA-5kn8A:
undetectable
4v3yB-5kn8A:
undetectable		 4v3yA-5kn8A:
22.28
4v3yB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 8 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.31A 4v3yA-5kn8A:
undetectable
4v3yB-5kn8A:
undetectable		 4v3yA-5kn8A:
22.28
4v3yB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 4v3zA-5kn8A:
undetectable
4v3zB-5kn8A:
undetectable		 4v3zA-5kn8A:
22.28
4v3zB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.31A 4v3zA-5kn8A:
undetectable
4v3zB-5kn8A:
undetectable		 4v3zA-5kn8A:
22.28
4v3zB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		5 / 12 GLU A 181
LEU A 134
ALA A 142
GLU A  43
ILE A 191
 None
 1.15A 4xe5A-5kn8A:
undetectable		 4xe5A-5kn8A:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.31A 5ad4A-5kn8A:
undetectable
5ad4B-5kn8A:
undetectable		 5ad4A-5kn8A:
22.28
5ad4B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.29A 5ad4A-5kn8A:
undetectable
5ad4B-5kn8A:
undetectable		 5ad4A-5kn8A:
22.28
5ad4B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.31A 5ad5A-5kn8A:
undetectable
5ad5B-5kn8A:
undetectable		 5ad5A-5kn8A:
22.28
5ad5B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.30A 5ad5A-5kn8A:
undetectable
5ad5B-5kn8A:
undetectable		 5ad5A-5kn8A:
22.28
5ad5B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.29A 5ad6A-5kn8A:
undetectable
5ad6B-5kn8A:
undetectable		 5ad6A-5kn8A:
22.28
5ad6B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.28A 5ad6A-5kn8A:
undetectable
5ad6B-5kn8A:
undetectable		 5ad6A-5kn8A:
22.28
5ad6B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.31A 5ad7A-5kn8A:
undetectable
5ad7B-5kn8A:
undetectable		 5ad7A-5kn8A:
22.28
5ad7B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.31A 5ad8A-5kn8A:
undetectable
5ad8B-5kn8A:
undetectable		 5ad8A-5kn8A:
22.28
5ad8B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.27A 5ad9A-5kn8A:
undetectable
5ad9B-5kn8A:
undetectable		 5ad9A-5kn8A:
22.28
5ad9B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.24A 5ad9A-5kn8A:
undetectable
5ad9B-5kn8A:
undetectable		 5ad9A-5kn8A:
22.28
5ad9B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.31A 5adaA-5kn8A:
undetectable
5adaB-5kn8A:
undetectable		 5adaA-5kn8A:
22.28
5adaB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.31A 5adaA-5kn8A:
undetectable
5adaB-5kn8A:
undetectable		 5adaA-5kn8A:
22.28
5adaB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 5adbA-5kn8A:
undetectable
5adbB-5kn8A:
undetectable		 5adbA-5kn8A:
22.28
5adbB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 5adcA-5kn8A:
undetectable
5adcB-5kn8A:
undetectable		 5adcA-5kn8A:
22.28
5adcB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 5adcA-5kn8A:
undetectable
5adcB-5kn8A:
undetectable		 5adcA-5kn8A:
22.28
5adcB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 5adeA-5kn8A:
undetectable
5adeB-5kn8A:
undetectable		 5adeA-5kn8A:
21.57
5adeB-5kn8A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 5adfA-5kn8A:
undetectable
5adfB-5kn8A:
undetectable		 5adfA-5kn8A:
21.21
5adfB-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.32A 5adgA-5kn8A:
undetectable
5adgB-5kn8A:
undetectable		 5adgA-5kn8A:
21.21
5adgB-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 5adgA-5kn8A:
undetectable
5adgB-5kn8A:
undetectable		 5adgA-5kn8A:
21.21
5adgB-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 5adiA-5kn8A:
undetectable
5adiB-5kn8A:
undetectable		 5adiA-5kn8A:
21.21
5adiB-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.35A 5agkA-5kn8A:
undetectable
5agkB-5kn8A:
undetectable		 5agkA-5kn8A:
22.28
5agkB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.31A 5agkA-5kn8A:
undetectable
5agkB-5kn8A:
undetectable		 5agkA-5kn8A:
22.28
5agkB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.32A 5aglA-5kn8A:
undetectable
5aglB-5kn8A:
undetectable		 5aglA-5kn8A:
22.28
5aglB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 5aglA-5kn8A:
undetectable
5aglB-5kn8A:
undetectable		 5aglA-5kn8A:
22.28
5aglB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 5agmA-5kn8A:
undetectable
5agmB-5kn8A:
undetectable		 5agmA-5kn8A:
22.28
5agmB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 5agnA-5kn8A:
undetectable
5agnB-5kn8A:
undetectable		 5agnA-5kn8A:
22.28
5agnB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 5agoA-5kn8A:
undetectable
5agoB-5kn8A:
undetectable		 5agoA-5kn8A:
22.28
5agoB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.31A 5agoA-5kn8A:
undetectable
5agoB-5kn8A:
undetectable		 5agoA-5kn8A:
22.28
5agoB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.37A 5agpA-5kn8A:
undetectable
5agpB-5kn8A:
undetectable		 5agpA-5kn8A:
22.28
5agpB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 5agpA-5kn8A:
undetectable
5agpB-5kn8A:
undetectable		 5agpA-5kn8A:
22.28
5agpB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_C_ACTC201_0
(NITROGEN REGULATORY
PROTEIN P-II)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 5 VAL A 131
VAL A 123
GLY A 124
PHE A 117
 None
None
CA  A 302 ( 4.3A)
None
 0.98A 5d4nA-5kn8A:
undetectable
5d4nC-5kn8A:
undetectable		 5d4nA-5kn8A:
19.58
5d4nC-5kn8A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 5fvpA-5kn8A:
undetectable
5fvpB-5kn8A:
undetectable		 5fvpA-5kn8A:
22.28
5fvpB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.31A 5fvpA-5kn8A:
undetectable
5fvpB-5kn8A:
undetectable		 5fvpA-5kn8A:
22.28
5fvpB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 5fvqA-5kn8A:
undetectable
5fvqB-5kn8A:
undetectable		 5fvqA-5kn8A:
22.28
5fvqB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.32A 5fvrA-5kn8A:
undetectable
5fvrB-5kn8A:
undetectable		 5fvrA-5kn8A:
22.28
5fvrB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 5fvsA-5kn8A:
undetectable
5fvsB-5kn8A:
undetectable		 5fvsA-5kn8A:
22.28
5fvsB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.36A 5fvtA-5kn8A:
undetectable
5fvtB-5kn8A:
undetectable		 5fvtA-5kn8A:
22.28
5fvtB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 5fvuA-5kn8A:
undetectable
5fvuB-5kn8A:
undetectable		 5fvuA-5kn8A:
21.21
5fvuB-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.30A 5fvuA-5kn8A:
undetectable
5fvuB-5kn8A:
undetectable		 5fvuA-5kn8A:
21.21
5fvuB-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.35A 5fvvA-5kn8A:
undetectable
5fvvB-5kn8A:
undetectable		 5fvvA-5kn8A:
21.21
5fvvB-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 5fvvA-5kn8A:
undetectable
5fvvB-5kn8A:
undetectable		 5fvvA-5kn8A:
21.21
5fvvB-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 5fvwA-5kn8A:
undetectable
5fvwB-5kn8A:
undetectable		 5fvwA-5kn8A:
21.21
5fvwB-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 5fw0A-5kn8A:
undetectable
5fw0B-5kn8A:
undetectable		 5fw0A-5kn8A:
22.28
5fw0B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 5fw0A-5kn8A:
undetectable
5fw0B-5kn8A:
undetectable		 5fw0A-5kn8A:
22.28
5fw0B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.35A 5g0nA-5kn8A:
undetectable
5g0nB-5kn8A:
undetectable		 5g0nA-5kn8A:
22.28
5g0nB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 5g0nA-5kn8A:
undetectable
5g0nB-5kn8A:
undetectable		 5g0nA-5kn8A:
22.28
5g0nB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.32A 5g0oA-5kn8A:
undetectable
5g0oB-5kn8A:
undetectable		 5g0oA-5kn8A:
22.28
5g0oB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 5g0oA-5kn8A:
undetectable
5g0oB-5kn8A:
undetectable		 5g0oA-5kn8A:
22.28
5g0oB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_C_FUAC1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		3 / 3 VAL A  44
HIS A  96
VAL A  99
 None
 0.72A 5jmnC-5kn8A:
undetectable		 5jmnC-5kn8A:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_2
(CYCLIN-DEPENDENT
KINASE 6)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		3 / 3 LYS A 228
GLN A  47
ASN A 144
 None
 1.04A 5l2tA-5kn8A:
undetectable		 5l2tA-5kn8A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_A_CVIA609_0
(ACETYLCHOLINESTERASE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 TYR A  89
ASP A  77
HIS A  96
TYR A  57
 None
 1.43A 5ov9A-5kn8A:
undetectable		 5ov9A-5kn8A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.30A 5unrA-5kn8A:
undetectable
5unrB-5kn8A:
undetectable		 5unrA-5kn8A:
22.28
5unrB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.32A 5unsA-5kn8A:
undetectable
5unsB-5kn8A:
undetectable		 5unsA-5kn8A:
22.28
5unsB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 5unsA-5kn8A:
undetectable
5unsB-5kn8A:
undetectable		 5unsA-5kn8A:
22.28
5unsB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.35A 5untA-5kn8A:
undetectable
5untB-5kn8A:
undetectable		 5untA-5kn8A:
22.28
5untB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 5untA-5kn8A:
undetectable
5untB-5kn8A:
undetectable		 5untA-5kn8A:
22.28
5untB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.36A 5unuA-5kn8A:
1.0
5unuB-5kn8A:
undetectable		 5unuA-5kn8A:
22.28
5unuB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 5unuA-5kn8A:
1.0
5unuB-5kn8A:
undetectable		 5unuA-5kn8A:
22.28
5unuB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.32A 5unvA-5kn8A:
undetectable
5unvB-5kn8A:
undetectable		 5unvA-5kn8A:
22.28
5unvB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.31A 5unvA-5kn8A:
undetectable
5unvB-5kn8A:
undetectable		 5unvA-5kn8A:
22.28
5unvB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.31A 5unwA-5kn8A:
undetectable
5unwB-5kn8A:
undetectable		 5unwA-5kn8A:
22.28
5unwB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 5unwA-5kn8A:
undetectable
5unwB-5kn8A:
undetectable		 5unwA-5kn8A:
22.28
5unwB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 5unxA-5kn8A:
undetectable
5unxB-5kn8A:
undetectable		 5unxA-5kn8A:
22.28
5unxB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 5unxA-5kn8A:
undetectable
5unxB-5kn8A:
undetectable		 5unxA-5kn8A:
22.28
5unxB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.36A 5unyA-5kn8A:
undetectable
5unyB-5kn8A:
undetectable		 5unyA-5kn8A:
22.28
5unyB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 5unyA-5kn8A:
undetectable
5unyB-5kn8A:
undetectable		 5unyA-5kn8A:
22.28
5unyB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 5unzA-5kn8A:
undetectable
5unzB-5kn8A:
undetectable		 5unzA-5kn8A:
22.28
5unzB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.30A 5uo0A-5kn8A:
undetectable
5uo0B-5kn8A:
undetectable		 5uo0A-5kn8A:
22.28
5uo0B-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.31A 5uo1A-5kn8A:
undetectable
5uo1B-5kn8A:
undetectable		 5uo1A-5kn8A:
21.21
5uo1B-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.31A 5uo1A-5kn8A:
1.1
5uo1B-5kn8A:
undetectable		 5uo1A-5kn8A:
21.21
5uo1B-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.35A 5uo2A-5kn8A:
undetectable
5uo2B-5kn8A:
undetectable		 5uo2A-5kn8A:
21.21
5uo2B-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 5uo2A-5kn8A:
undetectable
5uo2B-5kn8A:
undetectable		 5uo2A-5kn8A:
21.21
5uo2B-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.32A 5uo3A-5kn8A:
undetectable
5uo3B-5kn8A:
undetectable		 5uo3A-5kn8A:
21.21
5uo3B-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 5uo3A-5kn8A:
undetectable
5uo3B-5kn8A:
undetectable		 5uo3A-5kn8A:
21.21
5uo3B-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.32A 5uo4A-5kn8A:
undetectable
5uo4B-5kn8A:
undetectable		 5uo4A-5kn8A:
21.21
5uo4B-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 5uo4A-5kn8A:
undetectable
5uo4B-5kn8A:
undetectable		 5uo4A-5kn8A:
21.21
5uo4B-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 5uo5A-5kn8A:
undetectable
5uo5B-5kn8A:
undetectable		 5uo5A-5kn8A:
21.21
5uo5B-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 5uo5A-5kn8A:
undetectable
5uo5B-5kn8A:
undetectable		 5uo5A-5kn8A:
21.21
5uo5B-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 5uo6A-5kn8A:
undetectable
5uo6B-5kn8A:
undetectable		 5uo6A-5kn8A:
21.21
5uo6B-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 8 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.36A 5uo7A-5kn8A:
undetectable
5uo7B-5kn8A:
undetectable		 5uo7A-5kn8A:
21.21
5uo7B-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 5uo7A-5kn8A:
undetectable
5uo7B-5kn8A:
undetectable		 5uo7A-5kn8A:
21.21
5uo7B-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.29A 5vuiA-5kn8A:
undetectable
5vuiB-5kn8A:
undetectable		 5vuiA-5kn8A:
22.28
5vuiB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.31A 5vuiA-5kn8A:
undetectable
5vuiB-5kn8A:
undetectable		 5vuiA-5kn8A:
22.28
5vuiB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.28A 5vujA-5kn8A:
undetectable
5vujB-5kn8A:
undetectable		 5vujA-5kn8A:
22.28
5vujB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 5vujA-5kn8A:
undetectable
5vujB-5kn8A:
undetectable		 5vujA-5kn8A:
22.28
5vujB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.30A 5vukA-5kn8A:
undetectable
5vukB-5kn8A:
undetectable		 5vukA-5kn8A:
22.28
5vukB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.30A 5vukA-5kn8A:
undetectable
5vukB-5kn8A:
undetectable		 5vukA-5kn8A:
22.28
5vukB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 5vunA-5kn8A:
undetectable
5vunB-5kn8A:
undetectable		 5vunA-5kn8A:
22.28
5vunB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 5vuoA-5kn8A:
undetectable
5vuoB-5kn8A:
undetectable		 5vuoA-5kn8A:
22.28
5vuoB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 5vuoA-5kn8A:
undetectable
5vuoB-5kn8A:
undetectable		 5vuoA-5kn8A:
22.28
5vuoB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 5vupA-5kn8A:
undetectable
5vupB-5kn8A:
undetectable		 5vupA-5kn8A:
22.28
5vupB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 5vupA-5kn8A:
undetectable
5vupB-5kn8A:
undetectable		 5vupA-5kn8A:
22.28
5vupB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 5vuqA-5kn8A:
undetectable
5vuqB-5kn8A:
undetectable		 5vuqA-5kn8A:
22.28
5vuqB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.31A 5vuqA-5kn8A:
undetectable
5vuqB-5kn8A:
undetectable		 5vuqA-5kn8A:
22.28
5vuqB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.35A 5vusA-5kn8A:
undetectable
5vusB-5kn8A:
undetectable		 5vusA-5kn8A:
22.28
5vusB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 5vutA-5kn8A:
undetectable
5vutB-5kn8A:
undetectable		 5vutA-5kn8A:
22.28
5vutB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 5vutA-5kn8A:
undetectable
5vutB-5kn8A:
undetectable		 5vutA-5kn8A:
22.28
5vutB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 5vuuA-5kn8A:
undetectable
5vuuB-5kn8A:
undetectable		 5vuuA-5kn8A:
22.28
5vuuB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.29A 5vuuA-5kn8A:
undetectable
5vuuB-5kn8A:
undetectable		 5vuuA-5kn8A:
22.28
5vuuB-5kn8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 5vuvA-5kn8A:
undetectable
5vuvB-5kn8A:
undetectable		 5vuvA-5kn8A:
21.21
5vuvB-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 5vuvA-5kn8A:
undetectable
5vuvB-5kn8A:
undetectable		 5vuvA-5kn8A:
21.21
5vuvB-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.29A 5vuyA-5kn8A:
undetectable
5vuyB-5kn8A:
undetectable		 5vuyA-5kn8A:
21.21
5vuyB-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 5vuzA-5kn8A:
1.1
5vuzB-5kn8A:
undetectable		 5vuzA-5kn8A:
21.21
5vuzB-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 5vuzA-5kn8A:
1.1
5vuzB-5kn8A:
undetectable		 5vuzA-5kn8A:
21.21
5vuzB-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 5vv0A-5kn8A:
undetectable
5vv0B-5kn8A:
undetectable		 5vv0A-5kn8A:
21.46
5vv0B-5kn8A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 5vv0A-5kn8A:
undetectable
5vv0B-5kn8A:
undetectable		 5vv0A-5kn8A:
21.46
5vv0B-5kn8A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.35A 5vv1A-5kn8A:
undetectable
5vv1B-5kn8A:
undetectable		 5vv1A-5kn8A:
21.21
5vv1B-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 5vv1A-5kn8A:
undetectable
5vv1B-5kn8A:
undetectable		 5vv1A-5kn8A:
21.21
5vv1B-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.36A 5vv2A-5kn8A:
undetectable
5vv2B-5kn8A:
undetectable		 5vv2A-5kn8A:
21.21
5vv2B-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 5vv2A-5kn8A:
undetectable
5vv2B-5kn8A:
undetectable		 5vv2A-5kn8A:
21.21
5vv2B-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 5vv3A-5kn8A:
undetectable
5vv3B-5kn8A:
undetectable		 5vv3A-5kn8A:
21.21
5vv3B-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.30A 5vv3A-5kn8A:
undetectable
5vv3B-5kn8A:
undetectable		 5vv3A-5kn8A:
21.21
5vv3B-5kn8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.31A 6auqA-5kn8A:
undetectable
6auqB-5kn8A:
undetectable		 6auqA-5kn8A:
15.52
6auqB-5kn8A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 6auqA-5kn8A:
undetectable
6auqB-5kn8A:
undetectable		 6auqA-5kn8A:
15.52
6auqB-5kn8A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 6aurA-5kn8A:
undetectable
6aurB-5kn8A:
undetectable		 6aurA-5kn8A:
15.52
6aurB-5kn8A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 6aurA-5kn8A:
undetectable
6aurB-5kn8A:
undetectable		 6aurA-5kn8A:
15.52
6aurB-5kn8A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 6ausA-5kn8A:
undetectable
6ausB-5kn8A:
undetectable		 6ausA-5kn8A:
15.52
6ausB-5kn8A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 6ausA-5kn8A:
undetectable
6ausB-5kn8A:
undetectable		 6ausA-5kn8A:
15.52
6ausB-5kn8A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 6autA-5kn8A:
undetectable
6autB-5kn8A:
undetectable		 6autA-5kn8A:
15.52
6autB-5kn8A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.36A 6autA-5kn8A:
undetectable
6autB-5kn8A:
undetectable		 6autA-5kn8A:
15.52
6autB-5kn8A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 6auuA-5kn8A:
undetectable
6auuB-5kn8A:
undetectable		 6auuA-5kn8A:
15.52
6auuB-5kn8A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.32A 6auuA-5kn8A:
undetectable
6auuB-5kn8A:
undetectable		 6auuA-5kn8A:
15.52
6auuB-5kn8A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.35A 6auvA-5kn8A:
undetectable
6auvB-5kn8A:
undetectable		 6auvA-5kn8A:
15.52
6auvB-5kn8A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 6auvA-5kn8A:
1.0
6auvB-5kn8A:
undetectable		 6auvA-5kn8A:
15.52
6auvB-5kn8A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 6auwA-5kn8A:
undetectable
6auwB-5kn8A:
undetectable		 6auwA-5kn8A:
15.52
6auwB-5kn8A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 6auwA-5kn8A:
undetectable
6auwB-5kn8A:
undetectable		 6auwA-5kn8A:
15.52
6auwB-5kn8A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.36A 6auxA-5kn8A:
undetectable
6auxB-5kn8A:
undetectable		 6auxA-5kn8A:
15.52
6auxB-5kn8A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 6auxA-5kn8A:
undetectable
6auxB-5kn8A:
undetectable		 6auxA-5kn8A:
15.52
6auxB-5kn8A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.35A 6auyA-5kn8A:
undetectable
6auyB-5kn8A:
undetectable		 6auyA-5kn8A:
13.79
6auyB-5kn8A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 6auyA-5kn8A:
undetectable
6auyB-5kn8A:
undetectable		 6auyA-5kn8A:
13.79
6auyB-5kn8A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.38A 6auzA-5kn8A:
undetectable
6auzB-5kn8A:
undetectable		 6auzA-5kn8A:
13.79
6auzB-5kn8A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 6auzA-5kn8A:
undetectable
6auzB-5kn8A:
undetectable		 6auzA-5kn8A:
13.79
6auzB-5kn8A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.35A 6av0A-5kn8A:
undetectable
6av0B-5kn8A:
undetectable		 6av0A-5kn8A:
13.79
6av0B-5kn8A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 6av0A-5kn8A:
undetectable
6av0B-5kn8A:
undetectable		 6av0A-5kn8A:
13.79
6av0B-5kn8A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.30A 6av1A-5kn8A:
undetectable
6av1B-5kn8A:
undetectable		 6av1A-5kn8A:
13.79
6av1B-5kn8A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.36A 6av2A-5kn8A:
undetectable
6av2B-5kn8A:
undetectable		 6av2A-5kn8A:
13.79
6av2B-5kn8A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 6av2A-5kn8A:
undetectable
6av2B-5kn8A:
undetectable		 6av2A-5kn8A:
13.79
6av2B-5kn8A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.33A 6av3A-5kn8A:
undetectable
6av3B-5kn8A:
undetectable		 6av3A-5kn8A:
13.79
6av3B-5kn8A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 6av3A-5kn8A:
undetectable
6av3B-5kn8A:
undetectable		 6av3A-5kn8A:
13.79
6av3B-5kn8A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 6av4A-5kn8A:
undetectable
6av4B-5kn8A:
undetectable		 6av4A-5kn8A:
13.79
6av4B-5kn8A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 6av4A-5kn8A:
undetectable
6av4B-5kn8A:
undetectable		 6av4A-5kn8A:
13.79
6av4B-5kn8A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.36A 6av5A-5kn8A:
undetectable
6av5B-5kn8A:
undetectable		 6av5A-5kn8A:
13.79
6av5B-5kn8A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.35A 6av5A-5kn8A:
undetectable
6av5B-5kn8A:
undetectable		 6av5A-5kn8A:
13.79
6av5B-5kn8A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 6cicA-5kn8A:
undetectable
6cicB-5kn8A:
undetectable		 6cicA-5kn8A:
13.79
6cicB-5kn8A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_B_H4BB802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.34A 6cicA-5kn8A:
undetectable
6cicB-5kn8A:
undetectable		 6cicA-5kn8A:
13.79
6cicB-5kn8A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A  92
TRP A  83
PHE A  61
GLU A  84
 None
 1.34A 6cidA-5kn8A:
undetectable
6cidB-5kn8A:
undetectable		 6cidA-5kn8A:
13.79
6cidB-5kn8A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_B_H4BB803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A  83
PHE A  61
GLU A  84
VAL A  92
 None
 1.33A 6cidA-5kn8A:
undetectable
6cidB-5kn8A:
undetectable		 6cidA-5kn8A:
13.79
6cidB-5kn8A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECF_I_DVAI3010_0
(VLM2
DODECADEPSIPEPTIDE)		 5kn8 ADENINE DNA
GLYCOSYLASE
(Geobacillus
stearothermophil
us) 		3 / 3 PHE A  21
ARG A  31
ALA A 195
 None
 0.99A 6ecfB-5kn8A:
undetectable		 6ecfB-5kn8A:
20.19