SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kni'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)		 5kni TANKYRASE-1
(Homo
sapiens) 		4 / 7 ILE A1068
ARG A1044
PHE A1047
ILE A1031
 None
 1.07A 2qb4A-5kniA:
undetectable		 2qb4A-5kniA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJL_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5kni TANKYRASE-1
(Homo
sapiens) 		5 / 12 SER A1037
MET A1029
PHE A1047
LEU A1065
GLY A1074
 None
 1.11A 4zjlA-5kniA:
undetectable		 4zjlA-5kniA:
5.64