SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5knl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5knl UBIQUITIN-CONJUGATIN
G ENZYME E2 15
(Schizosaccharomy
ces
pombe) 		5 / 10 ILE C 122
ILE C 125
GLY C  44
PHE C  54
VAL C  40
 None
 1.41A 3elzB-5knlC:
undetectable		 3elzB-5knlC:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5knl UBIQUITIN-CONJUGATIN
G ENZYME E2 15
(Schizosaccharomy
ces
pombe) 		4 / 8 ASN C  86
HIS C  84
ASN C 138
ILE C  78
 None
 1.30A 3kp6A-5knlC:
undetectable
3kp6B-5knlC:
undetectable		 3kp6A-5knlC:
21.69
3kp6B-5knlC:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 5knl UBIQUITIN-CONJUGATIN
G ENZYME E2 15
(Schizosaccharomy
ces
pombe) 		3 / 3 PHE C  36
SER C   4
SER C   6
 None
 0.91A 3ufgB-5knlC:
undetectable		 3ufgB-5knlC:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)		 5knl UBIQUITIN-CONJUGATIN
G ENZYME E2 15
(Schizosaccharomy
ces
pombe) 		4 / 7 GLY C  87
VAL C  83
PRO C  85
ASN C  86
 None
 0.87A 4forA-5knlC:
undetectable		 4forA-5knlC:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 5knl UBIQUITIN-CONJUGATIN
G ENZYME E2 15
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU C 121
ILE C  91
VAL C  89
PHE C  74
MET C  72
 None
 1.23A 4y0pA-5knlC:
undetectable		 4y0pA-5knlC:
21.13