SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ko9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 5ko9 EMBRYONIC STEM
CELL-SPECIFIC
5-HYDROXYMETHYLCYTOS
INE-BINDING PROTEIN
(Homo
sapiens) 		4 / 6 LEU A 238
VAL A 102
VAL A 200
SER A  99
 None
 1.09A 1e7aB-5ko9A:
undetectable		 1e7aB-5ko9A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)		 5ko9 EMBRYONIC STEM
CELL-SPECIFIC
5-HYDROXYMETHYLCYTOS
INE-BINDING PROTEIN
(Homo
sapiens) 		4 / 8 ARG A  33
ALA A  71
ILE A  70
PRO A  30
 None
 0.98A 3fxrA-5ko9A:
undetectable		 3fxrA-5ko9A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 5ko9 EMBRYONIC STEM
CELL-SPECIFIC
5-HYDROXYMETHYLCYTOS
INE-BINDING PROTEIN
(Homo
sapiens) 		4 / 6 SER A   6
TYR A 126
VAL A 252
THR A 248
 None
 1.03A 3tneA-5ko9A:
undetectable		 3tneA-5ko9A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_1
(WBDD)		 5ko9 EMBRYONIC STEM
CELL-SPECIFIC
5-HYDROXYMETHYLCYTOS
INE-BINDING PROTEIN
(Homo
sapiens) 		4 / 6 GLN A  27
ASP A  22
GLU A  60
LEU A  29
 None
 1.11A 4ax8A-5ko9A:
undetectable		 4ax8A-5ko9A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA601_1
(SERUM ALBUMIN)		 5ko9 EMBRYONIC STEM
CELL-SPECIFIC
5-HYDROXYMETHYLCYTOS
INE-BINDING PROTEIN
(Homo
sapiens) 		5 / 11 LEU A 192
VAL A 191
PHE A  59
LEU A  54
SER A 194
 None
 1.30A 4zbqA-5ko9A:
undetectable		 4zbqA-5ko9A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_A_IPHA101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 5ko9 EMBRYONIC STEM
CELL-SPECIFIC
5-HYDROXYMETHYLCYTOS
INE-BINDING PROTEIN
(Homo
sapiens) 		4 / 4 CYH A   7
LEU A 173
LEU A  14
ALA A  17
 None
 0.97A 5hpuA-5ko9A:
undetectable
5hpuB-5ko9A:
undetectable		 5hpuA-5ko9A:
7.92
5hpuB-5ko9A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 5ko9 EMBRYONIC STEM
CELL-SPECIFIC
5-HYDROXYMETHYLCYTOS
INE-BINDING PROTEIN
(Homo
sapiens) 		5 / 12 LEU A 238
ILE A 179
THR A  94
LEU A 217
ALA A 215
 None
 1.13A 6djzA-5ko9A:
undetectable		 6djzA-5ko9A:
20.28