SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5koj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_F_CCSF47_0
(GLUTATHIONE
S-TRANSFERASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 5 THR A  74
LEU A 425
GLY A 422
LYS A 442
None
None
None
HCA  A 501 ( 4.2A)
1.36A 1gtiF-5kojA:
undetectable
1gtiF-5kojA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 6 TYR A 417
VAL A 447
ILE A 452
LEU A  17
None
1.27A 1j96A-5kojA:
undetectable
1j96A-5kojA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 5 TYR A 370
TYR A 417
ILE A 416
GLY A 372
None
None
None
ICS  A 502 (-3.5A)
1.15A 1kifA-5kojA:
2.8
1kifA-5kojA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 5 TYR A 395
TYR A 403
ILE A 416
GLY A 372
None
None
None
ICS  A 502 (-3.5A)
1.30A 1kifA-5kojA:
2.8
1kifA-5kojA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 5 TYR A 370
TYR A 417
ILE A 416
GLY A 372
None
None
None
ICS  A 502 (-3.5A)
1.15A 1kifB-5kojA:
2.8
1kifB-5kojA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 5 TYR A 395
TYR A 403
ILE A 416
GLY A 372
None
None
None
ICS  A 502 (-3.5A)
1.30A 1kifB-5kojA:
2.8
1kifB-5kojA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 5 TYR A 370
TYR A 417
ILE A 416
GLY A 372
None
None
None
ICS  A 502 (-3.5A)
1.15A 1kifC-5kojA:
undetectable
1kifC-5kojA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 5 TYR A 395
TYR A 403
ILE A 416
GLY A 372
None
None
None
ICS  A 502 (-3.5A)
1.30A 1kifC-5kojA:
undetectable
1kifC-5kojA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 5 TYR A 370
TYR A 417
ILE A 416
GLY A 372
None
None
None
ICS  A 502 (-3.5A)
1.15A 1kifD-5kojA:
undetectable
1kifD-5kojA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 5 TYR A 395
TYR A 403
ILE A 416
GLY A 372
None
None
None
ICS  A 502 (-3.5A)
1.29A 1kifD-5kojA:
undetectable
1kifD-5kojA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 5 TYR A 370
TYR A 417
ILE A 416
GLY A 372
None
None
None
ICS  A 502 (-3.5A)
1.15A 1kifE-5kojA:
undetectable
1kifE-5kojA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 5 TYR A 395
TYR A 403
ILE A 416
GLY A 372
None
None
None
ICS  A 502 (-3.5A)
1.30A 1kifE-5kojA:
undetectable
1kifE-5kojA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 5 TYR A 370
TYR A 417
ILE A 416
GLY A 372
None
None
None
ICS  A 502 (-3.5A)
1.15A 1kifF-5kojA:
2.8
1kifF-5kojA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 5 TYR A 395
TYR A 403
ILE A 416
GLY A 372
None
None
None
ICS  A 502 (-3.5A)
1.30A 1kifF-5kojA:
2.8
1kifF-5kojA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 5 TYR A 370
TYR A 417
ILE A 416
GLY A 372
None
None
None
ICS  A 502 (-3.5A)
1.15A 1kifG-5kojA:
undetectable
1kifG-5kojA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 5 TYR A 395
TYR A 403
ILE A 416
GLY A 372
None
None
None
ICS  A 502 (-3.5A)
1.29A 1kifG-5kojA:
undetectable
1kifG-5kojA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 5 TYR A 370
TYR A 417
ILE A 416
GLY A 372
None
None
None
ICS  A 502 (-3.5A)
1.15A 1kifH-5kojA:
undetectable
1kifH-5kojA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 5 TYR A 395
TYR A 403
ILE A 416
GLY A 372
None
None
None
ICS  A 502 (-3.5A)
1.29A 1kifH-5kojA:
undetectable
1kifH-5kojA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 5 TYR A 370
TYR A 417
ILE A 416
GLY A 372
None
None
None
ICS  A 502 (-3.5A)
1.15A 1ve9A-5kojA:
2.8
1ve9A-5kojA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 5 TYR A 395
TYR A 403
ILE A 416
GLY A 372
None
None
None
ICS  A 502 (-3.5A)
1.35A 1ve9A-5kojA:
2.8
1ve9A-5kojA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
5 / 12 GLY A 398
SER A 206
ASP A 402
ARG A 405
ASN A  65
None
1.22A 2bm9B-5kojA:
undetectable
2bm9B-5kojA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 5 TYR A 370
TYR A 417
ILE A 416
GLY A 372
None
None
None
ICS  A 502 (-3.5A)
1.18A 2du8G-5kojA:
2.8
2du8G-5kojA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 5 TYR A 395
TYR A 403
ILE A 416
GLY A 372
None
None
None
ICS  A 502 (-3.5A)
1.32A 2du8G-5kojA:
2.8
2du8G-5kojA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 5 TYR A 370
TYR A 417
ILE A 416
GLY A 372
None
None
None
ICS  A 502 (-3.5A)
1.21A 2du8J-5kojA:
2.8
2du8J-5kojA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 5 TYR A 395
TYR A 403
ILE A 416
GLY A 372
None
None
None
ICS  A 502 (-3.5A)
1.28A 2du8J-5kojA:
2.8
2du8J-5kojA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
3 / 3 GLU A 338
ASP A 333
TYR A 237
None
0.85A 2yvlB-5kojA:
undetectable
2yvlB-5kojA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_1
(HYPOTHETICAL PROTEIN)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 4 GLY A 339
GLU A 338
ASP A 333
TYR A 237
None
1.22A 2yvlC-5kojA:
2.3
2yvlC-5kojA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 8 GLY A  85
TRP A  88
TYR A 245
ARG A 112
None
None
ICS  A 502 (-4.1A)
ICS  A 502 (-4.1A)
1.40A 3ccfA-5kojA:
undetectable
3ccfA-5kojA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN Q5LES9)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
5 / 12 GLY A 210
GLY A  82
LEU A 209
ALA A 214
ASN A 215
None
1.09A 3kkzA-5kojA:
2.0
3kkzA-5kojA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
3 / 3 TYR A 417
MET A 388
LEU A 436
None
1.02A 3vw1D-5kojA:
undetectable
3vw1D-5kojA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_1
(HYDROXYINDOLE
O-METHYLTRANSFERASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
3 / 3 TYR A 370
ASP A 418
ASP A 402
None
0.68A 4a6eA-5kojA:
undetectable
4a6eA-5kojA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_ACTA303_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
3 / 3 TYR A 292
HIS A 399
ARG A 293
None
0.74A 4htfA-5kojA:
undetectable
4htfA-5kojA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7G_B_ACTB902_0
(3-HYDROXYPROLINE
DEHYDRATSE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 7 ASP A 244
SER A 253
HIS A 467
SER A 254
None
1.16A 4k7gB-5kojA:
undetectable
4k7gB-5kojA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 8 TYR A 383
TRP A 460
GLY A 440
ILE A  75
None
None
HCA  A 501 (-3.3A)
None
0.85A 4qoiA-5kojA:
undetectable
4qoiB-5kojA:
undetectable
4qoiA-5kojA:
16.73
4qoiB-5kojA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XNX_A_41XA707_1
(TRANSPORTER)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
5 / 11 ALA A  81
TYR A 245
GLY A 372
SER A 294
GLY A  82
HCA  A 501 (-3.3A)
ICS  A 502 (-4.1A)
ICS  A 502 (-3.5A)
ICS  A 502 ( 3.7A)
None
1.27A 4xnxA-5kojA:
undetectable
4xnxA-5kojA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 8 LYS A 162
SER A 124
THR A 120
ILE A 117
None
1.11A 5jhdE-5kojA:
undetectable
5jhdG-5kojA:
undetectable
5jhdE-5kojA:
17.80
5jhdG-5kojA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
5 / 12 GLY A 407
ARG A 377
ALA A  40
GLY A  41
ILE A 416
None
0.91A 5kb6B-5kojA:
2.5
5kb6B-5kojA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 7 LEU A 258
ILE A 298
MET A 295
TRP A 269
None
1.06A 5ljcA-5kojA:
undetectable
5ljcA-5kojA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
3 / 3 ASN A 114
VAL A 371
HIS A 458
None
ICS  A 502 ( 4.4A)
ICS  A 502 ( 3.6A)
0.75A 6a5yD-5kojA:
undetectable
6a5yD-5kojA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA715_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacte
r
diazotrophicus)
4 / 6 ASN A 246
ASP A 244
SER A 254
ARG A 255
None
1.10A 6dwdA-5kojA:
undetectable
6dwdC-5kojA:
undetectable
6dwdA-5kojA:
21.45
6dwdC-5kojA:
21.45