SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kol'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 5kol UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		3 / 3 ALA A  94
VAL A  89
TRP A 132
 None
 0.65A 1bdwA-5kolA:
undetectable
1bdwB-5kolA:
undetectable		 1bdwA-5kolA:
44.44
1bdwB-5kolA:
44.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 5kol UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		4 / 5 LEU A 164
ARG A 161
ALA A 163
ILE A  17
 None
None
None
CL  A 201 (-4.6A)
 1.18A 2qhfA-5kolA:
undetectable		 2qhfA-5kolA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 5kol UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		4 / 5 LEU A  28
ILE A  17
ARG A 161
TYR A  60
 None
CL  A 201 (-4.6A)
None
None
 1.34A 2zlcA-5kolA:
undetectable		 2zlcA-5kolA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5kol UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		4 / 6 GLU A 123
GLY A 122
GLY A 125
ASP A 124
 None
 0.87A 5a06D-5kolA:
undetectable		 5a06D-5kolA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AY4_A_TPFA506_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 5kol UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		5 / 10 MET A 146
PHE A 148
ALA A 159
PHE A 162
ALA A 163
 None
 1.46A 6ay4A-5kolA:
undetectable		 6ay4A-5kolA:
17.19