SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kp9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U52_A_CUA515_0
(PHENOL HYDROXYLASE
COMPONENT PHL
PHENOL HYDROXYLASE
COMPONENT PHN)		 5kp9 EPN-01*
(Thermotoga
maritima;
Human
immunodeficiency
virus
1) 		3 / 3 HIS B  35
HIS B   8
ILE B  62
 None
 0.85A 3u52A-5kp9B:
undetectable
3u52C-5kp9B:
undetectable		 3u52A-5kp9B:
20.31
3u52C-5kp9B:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 5kp9 EPN-01*
(Human
immunodeficiency
virus
1;
Thermotoga
maritima) 		4 / 5 LEU B  36
ILE B 125
ALA B 172
MET B 106
 None
 1.03A 4dc3B-5kp9B:
undetectable		 4dc3B-5kp9B:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_B_AERB602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 5kp9 EPN-01*
(Human
immunodeficiency
virus
1;
Thermotoga
maritima) 		5 / 9 ALA B  46
PHE B  41
VAL B 103
GLY B  64
VAL B  78
 None
 1.24A 4r20B-5kp9B:
undetectable		 4r20B-5kp9B:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 5kp9 EPN-01*
(Human
immunodeficiency
virus
1;
Thermotoga
maritima) 		4 / 4 VAL B 170
ILE B 198
ASN B 161
VAL B 175
 None
 1.26A 5ajqA-5kp9B:
undetectable		 5ajqA-5kp9B:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 5kp9 EPN-01*
(Thermotoga
maritima;
Human
immunodeficiency
virus
1) 		5 / 12 ILE B  85
VAL B  68
THR B  69
ILE B  94
HIS B  89
 None
 1.17A 6hlpA-5kp9B:
3.1		 6hlpA-5kp9B:
18.64