SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kpe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 6 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.06A 1dz4A-5kpeA:
undetectable		 1dz4A-5kpeA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 6 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.07A 1dz4B-5kpeA:
undetectable		 1dz4B-5kpeA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 8 LEU A  35
PHE A  94
VAL A  96
VAL A  71
 None
 0.76A 1epbB-5kpeA:
undetectable		 1epbB-5kpeA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 5 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.00A 1t88B-5kpeA:
undetectable		 1t88B-5kpeA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 7 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.00A 1yrcA-5kpeA:
undetectable		 1yrcA-5kpeA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 7 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.02A 1yrdA-5kpeA:
undetectable		 1yrdA-5kpeA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 5 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.02A 2m56A-5kpeA:
undetectable		 2m56A-5kpeA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 6 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.10A 2zawA-5kpeA:
undetectable		 2zawA-5kpeA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 7 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.03A 2zaxA-5kpeA:
undetectable		 2zaxA-5kpeA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 6 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 0.99A 2zuhA-5kpeA:
undetectable		 2zuhA-5kpeA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 6 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.07A 2zuiA-5kpeA:
undetectable		 2zuiA-5kpeA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 7 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.01A 2zwtA-5kpeA:
undetectable		 2zwtA-5kpeA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 7 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.03A 2zwuA-5kpeA:
undetectable		 2zwuA-5kpeA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 7 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.03A 3fwfA-5kpeA:
undetectable		 3fwfA-5kpeA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 7 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.01A 3fwfB-5kpeA:
undetectable		 3fwfB-5kpeA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 6 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.02A 3fwgA-5kpeA:
undetectable		 3fwgA-5kpeA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 7 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.03A 3fwgB-5kpeA:
undetectable		 3fwgB-5kpeA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 7 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.01A 3fwiA-5kpeA:
undetectable		 3fwiA-5kpeA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 7 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.02A 3fwjA-5kpeA:
undetectable		 3fwjA-5kpeA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 7 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.04A 3wrhA-5kpeA:
undetectable		 3wrhA-5kpeA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 6 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.03A 3wrhE-5kpeA:
undetectable		 3wrhE-5kpeA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 7 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.03A 3wrjA-5kpeA:
undetectable		 3wrjA-5kpeA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 6 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.05A 3wrjE-5kpeA:
undetectable		 3wrjE-5kpeA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 7 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.03A 3wrmA-5kpeA:
undetectable		 3wrmA-5kpeA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 6 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.02A 4ek1A-5kpeA:
undetectable		 4ek1A-5kpeA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 6 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.04A 4kkyX-5kpeA:
undetectable		 4kkyX-5kpeA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5kpe DE NOVO BETA SHEET
DESIGN PROTEIN OR664
(synthetic
construct) 		4 / 5 PHE A  94
LEU A  31
VAL A  39
VAL A 106
 None
 1.04A 4l49A-5kpeA:
undetectable		 4l49A-5kpeA:
14.25