SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kq1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_2
(WTFP-TAG,GP41)		 5kq1 MRNA DECAPPING
COMPLEX SUBUNIT 2
(Schizosaccharomy
ces
pombe) 		3 / 3 LEU B 226
LEU B 229
TRP B 232
 None
 0.90A 5nwuA-5kq1B:
undetectable		 5nwuA-5kq1B:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 5kq1 MRNA DECAPPING
COMPLEX SUBUNIT 2
(Schizosaccharomy
ces
pombe) 		4 / 8 PHE B 225
ARG B 167
ILE B 166
GLY B 168
 None
 0.73A 5nzxA-5kq1B:
undetectable		 5nzxA-5kq1B:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_2
(CYTOCHROME P450 2C9)		 5kq1 MRNA DECAPPING
COMPLEX SUBUNIT 2
(Schizosaccharomy
ces
pombe) 		4 / 4 PHE B 207
LEU B 173
LEU B 104
VAL B 222
 None
 1.21A 5xxiA-5kq1B:
undetectable		 5xxiA-5kq1B:
20.63