SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kqi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		6 / 8 HIS A 279
GLY A 282
LYS A 283
THR A 284
LEU A 386
ASP A 389
 HEM  A 801 (-3.2A)
HEM  A 801 (-3.3A)
None
HEM  A 801 (-3.9A)
None
None
 0.38A 1aegA-5kqiA:
32.5		 1aegA-5kqiA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		3 / 3 ALA A 295
VAL A 293
TRP A 309
 None
MPD  A 806 ( 4.6A)
None
 0.93A 1bdwA-5kqiA:
undetectable
1bdwB-5kqiA:
undetectable		 1bdwA-5kqiA:
3.39
1bdwB-5kqiA:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 PHE A 728
ALA A 724
GLY A 720
TYR A 719
 None
 0.99A 1c8lA-5kqiA:
undetectable		 1c8lA-5kqiA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 LYS A 620
LEU A 624
LEU A 626
VAL A 702
 None
 0.93A 1dvxB-5kqiA:
undetectable		 1dvxB-5kqiA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 PHE A 728
ALA A 724
GLY A 720
TYR A 719
 None
 0.94A 1gfzA-5kqiA:
undetectable		 1gfzA-5kqiA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_B_NIOB702_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 5 PHE A 187
GLY A 189
SER A 164
PHE A  72
 None
 1.34A 1icvA-5kqiA:
undetectable
1icvB-5kqiA:
undetectable		 1icvA-5kqiA:
14.13
1icvB-5kqiA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 VAL A 481
TRP A 736
PHE A 732
GLU A 560
 None
 1.48A 1k2sA-5kqiA:
undetectable
1k2sB-5kqiA:
undetectable		 1k2sA-5kqiA:
19.97
1k2sB-5kqiA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.47A 1k2sA-5kqiA:
undetectable
1k2sB-5kqiA:
undetectable		 1k2sA-5kqiA:
19.97
1k2sB-5kqiA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 VAL A 481
TRP A 736
PHE A 732
GLU A 560
 None
 1.49A 1k2tA-5kqiA:
undetectable
1k2tB-5kqiA:
undetectable		 1k2tA-5kqiA:
19.97
1k2tB-5kqiA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.48A 1k2tA-5kqiA:
undetectable
1k2tB-5kqiA:
undetectable		 1k2tA-5kqiA:
19.97
1k2tB-5kqiA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 VAL A 481
TRP A 736
PHE A 732
GLU A 560
 None
 1.48A 1k2uA-5kqiA:
undetectable
1k2uB-5kqiA:
undetectable		 1k2uA-5kqiA:
19.97
1k2uB-5kqiA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.48A 1k2uA-5kqiA:
undetectable
1k2uB-5kqiA:
undetectable		 1k2uA-5kqiA:
19.97
1k2uB-5kqiA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 PHE A 728
ALA A 724
GLY A 720
TYR A 719
 None
 0.98A 1l5qA-5kqiA:
undetectable		 1l5qA-5kqiA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 PHE A 728
ALA A 724
GLY A 720
TYR A 719
 None
 0.98A 1l5qB-5kqiA:
undetectable		 1l5qB-5kqiA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 PHE A 728
ALA A 724
GLY A 720
TYR A 719
 None
 0.96A 1l7xA-5kqiA:
undetectable		 1l7xA-5kqiA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 PHE A 728
ALA A 724
GLY A 720
TYR A 719
 None
 0.99A 1l7xB-5kqiA:
undetectable		 1l7xB-5kqiA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 1mmvA-5kqiA:
undetectable
1mmvB-5kqiA:
undetectable		 1mmvA-5kqiA:
19.97
1mmvB-5kqiA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 GLY A 636
GLY A 637
VAL A 559
LEU A 660
LEU A 641
 None
 1.07A 1mx1F-5kqiA:
undetectable		 1mx1F-5kqiA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		3 / 3 ARG A 123
ASP A 599
ASN A 603
 None
 0.94A 1nbhA-5kqiA:
undetectable		 1nbhA-5kqiA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		3 / 3 ARG A 123
ASP A 599
ASN A 603
 None
 0.92A 1nbhD-5kqiA:
undetectable		 1nbhD-5kqiA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 8 VAL A 481
TRP A 736
PHE A 732
GLU A 560
 None
 1.48A 1om5A-5kqiA:
undetectable
1om5B-5kqiA:
undetectable		 1om5A-5kqiA:
20.28
1om5B-5kqiA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.45A 1om5A-5kqiA:
undetectable
1om5B-5kqiA:
undetectable		 1om5A-5kqiA:
20.28
1om5B-5kqiA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 1p6hA-5kqiA:
undetectable
1p6hB-5kqiA:
undetectable		 1p6hA-5kqiA:
20.28
1p6hB-5kqiA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.50A 1p6jA-5kqiA:
undetectable
1p6jB-5kqiA:
undetectable		 1p6jA-5kqiA:
20.28
1p6jB-5kqiA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 LYS A 620
LEU A 624
LEU A 626
SER A 627
 None
 0.92A 1tz8C-5kqiA:
undetectable
1tz8D-5kqiA:
undetectable		 1tz8C-5kqiA:
12.89
1tz8D-5kqiA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_D_DESD128_1
(TRANSTHYRETIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 4 LYS A 620
LEU A 624
LEU A 626
SER A 627
 None
 1.29A 1tz8D-5kqiA:
undetectable		 1tz8D-5kqiA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_B_CHDB4085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE II
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 11 GLY A 104
THR A 333
THR A 331
PHE A 182
GLY A 277
 HEM  A 801 (-3.4A)
None
None
None
None
 1.44A 1v54A-5kqiA:
undetectable
1v54B-5kqiA:
undetectable
1v54T-5kqiA:
undetectable		 1v54A-5kqiA:
20.60
1v54B-5kqiA:
16.18
1v54T-5kqiA:
8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 528
LEU A 475
GLY A 555
ALA A 484
ALA A 488
 None
 0.98A 2bm9A-5kqiA:
undetectable		 2bm9A-5kqiA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 528
LEU A 475
GLY A 555
ALA A 484
ALA A 488
 None
 0.92A 2bm9C-5kqiA:
undetectable		 2bm9C-5kqiA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 528
LEU A 475
GLY A 555
ALA A 484
ALA A 488
 None
 0.99A 2bm9D-5kqiA:
undetectable		 2bm9D-5kqiA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 528
LEU A 475
GLY A 555
ALA A 484
ALA A 488
 None
 1.03A 2bm9E-5kqiA:
undetectable		 2bm9E-5kqiA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 528
LEU A 475
GLY A 555
ALA A 484
ALA A 488
 None
 1.00A 2br4A-5kqiA:
undetectable		 2br4A-5kqiA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 528
LEU A 475
GLY A 555
ALA A 484
ALA A 488
 None
 0.97A 2br4C-5kqiA:
undetectable		 2br4C-5kqiA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 528
LEU A 475
GLY A 555
ALA A 484
ALA A 488
 None
 1.01A 2br4D-5kqiA:
undetectable		 2br4D-5kqiA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 528
LEU A 475
GLY A 555
ALA A 484
ALA A 488
 None
 0.99A 2br4E-5kqiA:
undetectable		 2br4E-5kqiA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		3 / 3 GLN A 131
THR A 323
TRP A  95
 None
HEM  A 801 (-3.4A)
None
 1.15A 2rctA-5kqiA:
undetectable		 2rctA-5kqiA:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_B_CHDB1086_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 11 GLY A 104
THR A 333
THR A 331
PHE A 182
GLY A 277
 HEM  A 801 (-3.4A)
None
None
None
None
 1.42A 2zxwA-5kqiA:
1.8
2zxwB-5kqiA:
undetectable
2zxwT-5kqiA:
undetectable		 2zxwA-5kqiA:
20.60
2zxwB-5kqiA:
16.18
2zxwT-5kqiA:
8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_G_CHDG86_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 11 PHE A 182
GLY A 277
GLY A 104
THR A 333
THR A 331
 None
None
HEM  A 801 (-3.4A)
None
None
 1.47A 2zxwG-5kqiA:
undetectable
2zxwN-5kqiA:
undetectable
2zxwO-5kqiA:
undetectable		 2zxwG-5kqiA:
8.52
2zxwN-5kqiA:
20.60
2zxwO-5kqiA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_B_CHDB1086_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 11 GLY A 104
THR A 333
THR A 331
PHE A 182
GLY A 277
 HEM  A 801 (-3.4A)
None
None
None
None
 1.47A 3ablA-5kqiA:
undetectable
3ablB-5kqiA:
undetectable
3ablT-5kqiA:
undetectable		 3ablA-5kqiA:
20.60
3ablB-5kqiA:
16.18
3ablT-5kqiA:
8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_B_CHDB1086_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 11 GLY A 104
THR A 333
THR A 331
PHE A 182
GLY A 277
 HEM  A 801 (-3.4A)
None
None
None
None
 1.49A 3abmA-5kqiA:
1.6
3abmB-5kqiA:
undetectable
3abmT-5kqiA:
undetectable		 3abmA-5kqiA:
20.60
3abmB-5kqiA:
16.18
3abmT-5kqiA:
8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 10 PHE A 182
GLY A 277
GLY A 104
THR A 333
THR A 331
 None
None
HEM  A 801 (-3.4A)
None
None
 1.47A 3abmG-5kqiA:
undetectable
3abmN-5kqiA:
undetectable
3abmO-5kqiA:
undetectable		 3abmG-5kqiA:
8.52
3abmN-5kqiA:
20.60
3abmO-5kqiA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 11 GLY A 104
THR A 333
THR A 331
PHE A 182
GLY A 277
 HEM  A 801 (-3.4A)
None
None
None
None
 1.46A 3ag1A-5kqiA:
0.3
3ag1B-5kqiA:
undetectable
3ag1T-5kqiA:
undetectable		 3ag1A-5kqiA:
20.60
3ag1B-5kqiA:
16.18
3ag1T-5kqiA:
8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 11 PHE A 182
GLY A 277
GLY A 104
THR A 333
THR A 331
 None
None
HEM  A 801 (-3.4A)
None
None
 1.45A 3ag1G-5kqiA:
undetectable
3ag1N-5kqiA:
0.1
3ag1O-5kqiA:
undetectable		 3ag1G-5kqiA:
8.52
3ag1N-5kqiA:
20.60
3ag1O-5kqiA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 10 PHE A 182
GLY A 277
GLY A 104
THR A 333
THR A 331
 None
None
HEM  A 801 (-3.4A)
None
None
 1.48A 3ag4G-5kqiA:
undetectable
3ag4N-5kqiA:
0.1
3ag4O-5kqiA:
undetectable		 3ag4G-5kqiA:
8.52
3ag4N-5kqiA:
20.60
3ag4O-5kqiA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 3b3nA-5kqiA:
undetectable
3b3nB-5kqiA:
undetectable		 3b3nA-5kqiA:
20.85
3b3nB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.50A 3b3oA-5kqiA:
undetectable
3b3oB-5kqiA:
undetectable		 3b3oA-5kqiA:
20.85
3b3oB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 8 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.46A 3b3pA-5kqiA:
undetectable
3b3pB-5kqiA:
undetectable		 3b3pA-5kqiA:
20.85
3b3pB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 5 PHE A 728
ALA A 724
GLY A 720
TYR A 719
 None
 0.98A 3bcrA-5kqiA:
undetectable		 3bcrA-5kqiA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_1
(PHOSPHOLIPASE A2)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 5 VAL A 652
PHE A 601
ARG A 649
ARG A 656
 None
None
None
MPD  A 808 ( 4.0A)
 1.30A 3bjwE-5kqiA:
undetectable		 3bjwE-5kqiA:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_2
(RENIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 5 TYR A 201
ALA A 120
ALA A 231
TYR A 238
 None
None
None
TOX  A 111 ( 2.9A)
 1.10A 3d91A-5kqiA:
undetectable		 3d91A-5kqiA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 PHE A 728
ALA A 724
GLY A 720
TYR A 719
 None
 0.99A 3dd1A-5kqiA:
undetectable		 3dd1A-5kqiA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 PHE A 728
ALA A 724
GLY A 720
TYR A 719
 None
 0.93A 3dd1B-5kqiA:
undetectable		 3dd1B-5kqiA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 PHE A 728
ALA A 724
GLY A 720
TYR A 719
 None
 0.97A 3ddsA-5kqiA:
undetectable		 3ddsA-5kqiA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 PHE A 728
ALA A 724
GLY A 720
TYR A 719
 None
 0.96A 3ddsB-5kqiA:
undetectable		 3ddsB-5kqiA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 PHE A 728
ALA A 724
GLY A 720
TYR A 719
 None
 0.95A 3ddwA-5kqiA:
undetectable		 3ddwA-5kqiA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 PHE A 728
ALA A 724
GLY A 720
TYR A 719
 None
 0.96A 3ddwB-5kqiA:
undetectable		 3ddwB-5kqiA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		3 / 3 MET A 428
MET A 264
PHE A 421
 None
 1.37A 3gn8A-5kqiA:
undetectable		 3gn8A-5kqiA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 VAL A 481
TRP A 736
PHE A 732
GLU A 560
 None
 1.49A 3hspA-5kqiA:
undetectable
3hspB-5kqiA:
undetectable		 3hspA-5kqiA:
20.85
3hspB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.50A 3jt4A-5kqiA:
1.4
3jt4B-5kqiA:
undetectable		 3jt4A-5kqiA:
20.85
3jt4B-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 3jwvA-5kqiA:
undetectable
3jwvB-5kqiA:
undetectable		 3jwvA-5kqiA:
20.55
3jwvB-5kqiA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 GLY A 125
ALA A 231
ASP A 121
GLY A 203
ARG A 218
 NA  A 802 ( 4.8A)
None
None
None
None
 1.34A 3jzjA-5kqiA:
undetectable		 3jzjA-5kqiA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_2
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		3 / 3 ARG A 602
THR A 654
THR A 476
 None
 0.57A 3k2hB-5kqiA:
undetectable		 3k2hB-5kqiA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 528
LEU A 521
SER A 546
GLY A 555
ALA A 484
 None
 1.11A 3kk6A-5kqiA:
undetectable		 3kk6A-5kqiA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 4 GLY A 124
TYR A 117
GLY A 122
ASP A 495
 CL  A 803 ( 4.0A)
None
NA  A 802 (-4.7A)
None
 1.36A 3kl3A-5kqiA:
undetectable		 3kl3A-5kqiA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 4 GLY A 125
TYR A 117
GLY A 122
ASP A 495
 NA  A 802 ( 4.8A)
None
NA  A 802 (-4.7A)
None
 1.11A 3kl3A-5kqiA:
undetectable		 3kl3A-5kqiA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL201_1
(PROTEIN S100-A4)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 GLY A 699
PHE A 732
PHE A 728
PHE A 665
 None
 1.14A 3ko0L-5kqiA:
undetectable
3ko0N-5kqiA:
undetectable		 3ko0L-5kqiA:
9.19
3ko0N-5kqiA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 466
VAL A 470
SER A 473
VAL A 545
LEU A 547
 None
 1.32A 3m7rA-5kqiA:
undetectable		 3m7rA-5kqiA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		6 / 12 ALA A 563
ALA A 659
ALA A 566
VAL A 570
ALA A 557
GLY A 558
 None
 1.15A 3mg0Y-5kqiA:
undetectable
3mg0Z-5kqiA:
undetectable		 3mg0Y-5kqiA:
14.55
3mg0Z-5kqiA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 VAL A 481
TRP A 736
PHE A 732
GLU A 560
 None
 1.49A 3n5vA-5kqiA:
undetectable
3n5vB-5kqiA:
undetectable		 3n5vA-5kqiA:
20.85
3n5vB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.46A 3n5vA-5kqiA:
undetectable
3n5vB-5kqiA:
undetectable		 3n5vA-5kqiA:
20.85
3n5vB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.48A 3n5zA-5kqiA:
undetectable
3n5zB-5kqiA:
undetectable		 3n5zA-5kqiA:
20.85
3n5zB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 3nlkA-5kqiA:
undetectable
3nlkB-5kqiA:
undetectable		 3nlkA-5kqiA:
20.55
3nlkB-5kqiA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 3nlnA-5kqiA:
undetectable
3nlnB-5kqiA:
undetectable		 3nlnA-5kqiA:
20.55
3nlnB-5kqiA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 VAL A 481
TRP A 736
PHE A 732
GLU A 560
 None
 1.50A 3nlyA-5kqiA:
undetectable
3nlyB-5kqiA:
undetectable		 3nlyA-5kqiA:
20.85
3nlyB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 VAL A 524
LEU A 528
LEU A 521
GLY A 555
ALA A 484
 None
 1.09A 3nt1A-5kqiA:
undetectable		 3nt1A-5kqiA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 VAL A 524
LEU A 528
LEU A 521
GLY A 555
ALA A 484
 None
 1.10A 3nt1B-5kqiA:
undetectable		 3nt1B-5kqiA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_1
(FIV PROTEASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 10 LEU A 634
ALA A 621
GLY A 493
VAL A 735
LEU A 626
 None
 0.88A 3ogpA-5kqiA:
undetectable		 3ogpA-5kqiA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 635
GLU A 717
ALA A 716
ASP A 703
LEU A 668
 None
 1.32A 3ou6D-5kqiA:
undetectable		 3ou6D-5kqiA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 3rqkA-5kqiA:
0.3
3rqkB-5kqiA:
undetectable		 3rqkA-5kqiA:
20.85
3rqkB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.50A 3svpA-5kqiA:
undetectable
3svpB-5kqiA:
undetectable		 3svpA-5kqiA:
20.85
3svpB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOU_A_ACTA228_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 4 ALA A 265
ARG A 497
TYR A 117
ARG A 426
 None
 1.36A 3touA-5kqiA:
0.0		 3touA-5kqiA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 VAL A 481
TRP A 736
PHE A 732
GLU A 560
 None
 1.48A 3ufoA-5kqiA:
undetectable
3ufoB-5kqiA:
undetectable		 3ufoA-5kqiA:
20.85
3ufoB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.47A 3ufoA-5kqiA:
undetectable
3ufoB-5kqiA:
undetectable		 3ufoA-5kqiA:
20.85
3ufoB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 VAL A 481
TRP A 736
PHE A 732
GLU A 560
 None
 1.48A 3ufpA-5kqiA:
undetectable
3ufpB-5kqiA:
1.8		 3ufpA-5kqiA:
20.85
3ufpB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 3ufqA-5kqiA:
undetectable
3ufqB-5kqiA:
undetectable		 3ufqA-5kqiA:
20.85
3ufqB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 VAL A 481
TRP A 736
PHE A 732
GLU A 560
 None
 1.47A 3ufrA-5kqiA:
undetectable
3ufrB-5kqiA:
undetectable		 3ufrA-5kqiA:
20.85
3ufrB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 3ufsA-5kqiA:
undetectable
3ufsB-5kqiA:
undetectable		 3ufsA-5kqiA:
20.85
3ufsB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.48A 3uftA-5kqiA:
undetectable
3uftB-5kqiA:
undetectable		 3uftA-5kqiA:
20.85
3uftB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 ILE A 551
GLY A 499
ILE A 505
ARG A 744
LEU A 624
 None
 0.90A 3uj6A-5kqiA:
undetectable		 3uj6A-5kqiA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_A_SALA1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 9 LEU A 635
PHE A 664
VAL A 705
LEU A 712
ALA A 716
 None
 1.22A 3unaA-5kqiA:
2.1		 3unaA-5kqiA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 9 LEU A 635
PHE A 664
VAL A 705
LEU A 712
ALA A 716
 None
 1.23A 3unaB-5kqiA:
undetectable		 3unaB-5kqiA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_A_SALA1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 9 LEU A 635
PHE A 664
VAL A 705
LEU A 712
ALA A 716
 None
 1.20A 3uncA-5kqiA:
undetectable		 3uncA-5kqiA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_B_SALB1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 9 LEU A 635
PHE A 664
VAL A 705
LEU A 712
ALA A 716
 None
 1.21A 3uncB-5kqiA:
undetectable		 3uncB-5kqiA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 PHE A 664
VAL A 705
LEU A 712
ALA A 716
 None
 0.95A 3uniA-5kqiA:
2.1		 3uniA-5kqiA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 11 GLY A 104
THR A 333
THR A 331
PHE A 182
GLY A 277
 HEM  A 801 (-3.4A)
None
None
None
None
 1.48A 3wg7A-5kqiA:
undetectable
3wg7B-5kqiA:
undetectable
3wg7T-5kqiA:
undetectable		 3wg7A-5kqiA:
20.60
3wg7B-5kqiA:
16.18
3wg7T-5kqiA:
8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 11 GLY A 104
THR A 333
THR A 331
PHE A 182
GLY A 277
 HEM  A 801 (-3.4A)
None
None
None
None
 1.50A 3x2qA-5kqiA:
undetectable
3x2qB-5kqiA:
undetectable
3x2qT-5kqiA:
undetectable		 3x2qA-5kqiA:
20.60
3x2qB-5kqiA:
16.18
3x2qT-5kqiA:
8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 4cdtA-5kqiA:
undetectable
4cdtB-5kqiA:
undetectable		 4cdtA-5kqiA:
20.85
4cdtB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.47A 4cttA-5kqiA:
undetectable
4cttB-5kqiA:
undetectable		 4cttA-5kqiA:
20.85
4cttB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.50A 4cx6A-5kqiA:
undetectable
4cx6B-5kqiA:
undetectable		 4cx6A-5kqiA:
20.85
4cx6B-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 4d2yA-5kqiA:
undetectable
4d2yB-5kqiA:
undetectable		 4d2yA-5kqiA:
20.85
4d2yB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 VAL A 481
TRP A 736
PHE A 732
GLU A 560
 None
 1.50A 4d2zA-5kqiA:
undetectable
4d2zB-5kqiA:
undetectable		 4d2zA-5kqiA:
20.85
4d2zB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 4d2zA-5kqiA:
undetectable
4d2zB-5kqiA:
undetectable		 4d2zA-5kqiA:
20.85
4d2zB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.48A 4d31A-5kqiA:
undetectable
4d31B-5kqiA:
undetectable		 4d31A-5kqiA:
20.85
4d31B-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 ARG A 118
GLY A 124
ASN A 142
GLN A 622
 None
CL  A 803 ( 4.0A)
None
None
 1.26A 4g0vB-5kqiA:
undetectable		 4g0vB-5kqiA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.50A 4gqeA-5kqiA:
undetectable
4gqeB-5kqiA:
undetectable		 4gqeA-5kqiA:
20.85
4gqeB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 VAL A 481
TRP A 736
PHE A 732
GLU A 560
 None
 1.49A 4imwA-5kqiA:
undetectable
4imwB-5kqiA:
undetectable		 4imwA-5kqiA:
20.85
4imwB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA805_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 4imwA-5kqiA:
undetectable
4imwB-5kqiA:
undetectable		 4imwA-5kqiA:
20.85
4imwB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 5 LYS A 422
LEU A 423
GLU A 270
LEU A 274
 None
TOX  A 111 ( 4.5A)
None
HEM  A 801 (-4.1A)
 1.32A 4k4yA-5kqiA:
undetectable		 4k4yA-5kqiA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 4 LYS A 422
LEU A 423
GLU A 270
LEU A 274
 None
TOX  A 111 ( 4.5A)
None
HEM  A 801 (-4.1A)
 1.33A 4k4yE-5kqiA:
undetectable		 4k4yE-5kqiA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 5 LYS A 422
LEU A 423
GLU A 270
LEU A 274
 None
TOX  A 111 ( 4.5A)
None
HEM  A 801 (-4.1A)
 1.35A 4k4yI-5kqiA:
undetectable		 4k4yI-5kqiA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.48A 4kciA-5kqiA:
undetectable
4kciB-5kqiA:
undetectable		 4kciA-5kqiA:
20.85
4kciB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_1
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		6 / 12 LEU A 168
LEU A 152
ILE A 155
PHE A 106
GLY A 173
LEU A 171
 None
None
MPD  A 807 ( 4.9A)
None
None
None
 1.15A 4lmnA-5kqiA:
undetectable		 4lmnA-5kqiA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NED_A_PFNA709_1
(LACTOTRANSFERRIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 ASP A 549
VAL A 453
ALA A 575
PHE A 574
 None
 1.08A 4nedA-5kqiA:
undetectable		 4nedA-5kqiA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NSB_A_AINA402_1
(CHITINASE-3-LIKE
PROTEIN 1)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 THR A 323
ARG A 108
TRP A  95
LEU A 105
 HEM  A 801 (-3.4A)
OXY  A 804 (-4.1A)
None
HEM  A 801 (-4.1A)
 1.36A 4nsbA-5kqiA:
undetectable		 4nsbA-5kqiA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_1
(ANDROGEN RECEPTOR)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 638
GLY A 637
LEU A 660
VAL A 477
THR A 654
 None
 1.04A 4ojbA-5kqiA:
undetectable		 4ojbA-5kqiA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 638
GLY A 637
LEU A 660
VAL A 477
THR A 654
 None
 1.07A 4ok1A-5kqiA:
undetectable		 4ok1A-5kqiA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 638
GLY A 637
LEU A 660
VAL A 477
THR A 654
 None
 1.02A 4okbA-5kqiA:
undetectable		 4okbA-5kqiA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 638
GLY A 637
LEU A 660
VAL A 477
THR A 654
 None
 1.06A 4okxA-5kqiA:
undetectable		 4okxA-5kqiA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 638
GLY A 637
LEU A 660
VAL A 477
THR A 654
 None
 1.13A 4olmA-5kqiA:
undetectable		 4olmA-5kqiA:
14.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 6 ASP A  98
TYR A 102
LEU A 105
HIS A 285
THR A 323
 None
None
HEM  A 801 (-4.1A)
HEM  A 801 (-3.7A)
HEM  A 801 (-3.4A)
 0.28A 4paeA-5kqiA:
62.4		 4paeA-5kqiA:
61.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.50A 4uh0A-5kqiA:
undetectable
4uh0B-5kqiA:
0.2		 4uh0A-5kqiA:
20.85
4uh0B-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.50A 4uh2A-5kqiA:
undetectable
4uh2B-5kqiA:
undetectable		 4uh2A-5kqiA:
20.85
4uh2B-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.48A 4upnA-5kqiA:
undetectable
4upnB-5kqiA:
undetectable		 4upnA-5kqiA:
20.85
4upnB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 VAL A 481
TRP A 736
PHE A 732
GLU A 560
 None
 1.45A 4v3wA-5kqiA:
undetectable
4v3wB-5kqiA:
undetectable		 4v3wA-5kqiA:
20.85
4v3wB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.47A 4v3wA-5kqiA:
undetectable
4v3wB-5kqiA:
undetectable		 4v3wA-5kqiA:
20.85
4v3wB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.48A 4v3zA-5kqiA:
undetectable
4v3zB-5kqiA:
undetectable		 4v3zA-5kqiA:
20.85
4v3zB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA407_0
(FAD:PROTEIN FMN
TRANSFERASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		3 / 3 ASP A 689
GLY A 672
ASP A 670
 None
 0.69A 4xdtA-5kqiA:
undetectable		 4xdtA-5kqiA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVC_A_BEZA301_0
(DIGUANYLATE CYCLASE
DOSC)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 8 ILE A 505
LEU A 521
ILE A 551
LEU A 547
 None
 0.69A 4zvcA-5kqiA:
undetectable
4zvcB-5kqiA:
1.7		 4zvcA-5kqiA:
10.31
4zvcB-5kqiA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVC_A_BEZA301_0
(DIGUANYLATE CYCLASE
DOSC)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 8 ILE A 551
LEU A 547
ILE A 505
LEU A 521
 None
 0.68A 4zvcA-5kqiA:
undetectable
4zvcB-5kqiA:
1.7		 4zvcA-5kqiA:
10.31
4zvcB-5kqiA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 VAL A 481
TRP A 736
PHE A 732
GLU A 560
 None
 1.48A 5ad4A-5kqiA:
undetectable
5ad4B-5kqiA:
undetectable		 5ad4A-5kqiA:
20.85
5ad4B-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.44A 5ad4A-5kqiA:
undetectable
5ad4B-5kqiA:
undetectable		 5ad4A-5kqiA:
20.85
5ad4B-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 VAL A 481
TRP A 736
PHE A 732
GLU A 560
 None
 1.49A 5ad5A-5kqiA:
undetectable
5ad5B-5kqiA:
undetectable		 5ad5A-5kqiA:
20.85
5ad5B-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.48A 5ad5A-5kqiA:
undetectable
5ad5B-5kqiA:
undetectable		 5ad5A-5kqiA:
20.85
5ad5B-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.48A 5ad6A-5kqiA:
undetectable
5ad6B-5kqiA:
1.1		 5ad6A-5kqiA:
20.85
5ad6B-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 5ad8A-5kqiA:
undetectable
5ad8B-5kqiA:
undetectable		 5ad8A-5kqiA:
20.85
5ad8B-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.47A 5ad9A-5kqiA:
undetectable
5ad9B-5kqiA:
undetectable		 5ad9A-5kqiA:
20.85
5ad9B-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 VAL A 481
TRP A 736
PHE A 732
GLU A 560
 None
 1.49A 5adaA-5kqiA:
undetectable
5adaB-5kqiA:
undetectable		 5adaA-5kqiA:
20.85
5adaB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.50A 5adbA-5kqiA:
undetectable
5adbB-5kqiA:
undetectable		 5adbA-5kqiA:
20.85
5adbB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 VAL A 481
TRP A 736
PHE A 732
GLU A 560
 None
 1.50A 5adiA-5kqiA:
undetectable
5adiB-5kqiA:
undetectable		 5adiA-5kqiA:
19.59
5adiB-5kqiA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 5agkA-5kqiA:
undetectable
5agkB-5kqiA:
undetectable		 5agkA-5kqiA:
20.85
5agkB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.50A 5agoA-5kqiA:
undetectable
5agoB-5kqiA:
undetectable		 5agoA-5kqiA:
20.85
5agoB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 5 LYS A 620
LEU A 624
LEU A 626
VAL A 702
 None
 0.88A 5cr1A-5kqiA:
undetectable		 5cr1A-5kqiA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CVT_B_ACTB200_0
(N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		3 / 3 ASN A 516
ALA A 515
ARG A 602
 None
 0.75A 5cvtB-5kqiA:
undetectable		 5cvtB-5kqiA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 5fvpA-5kqiA:
undetectable
5fvpB-5kqiA:
undetectable		 5fvpA-5kqiA:
20.85
5fvpB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.50A 5g0oA-5kqiA:
undetectable
5g0oB-5kqiA:
undetectable		 5g0oA-5kqiA:
21.11
5g0oB-5kqiA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 8 ASN A 603
TRP A 675
PHE A 685
THR A 632
 None
 1.37A 5hqaA-5kqiA:
undetectable		 5hqaA-5kqiA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 8 TRP A 337
PHE A 416
HIS A 406
THR A 329
 None
 1.38A 5hqaA-5kqiA:
undetectable		 5hqaA-5kqiA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_G_CHDG102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 10 PHE A 182
GLY A 277
GLY A 104
THR A 333
THR A 331
 None
None
HEM  A 801 (-3.4A)
None
None
 1.47A 5iy5G-5kqiA:
undetectable
5iy5N-5kqiA:
0.0
5iy5O-5kqiA:
undetectable		 5iy5G-5kqiA:
8.20
5iy5N-5kqiA:
20.60
5iy5O-5kqiA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_T_CHDT103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 10 GLY A 104
THR A 333
THR A 331
PHE A 182
GLY A 277
 HEM  A 801 (-3.4A)
None
None
None
None
 1.48A 5iy5A-5kqiA:
0.1
5iy5B-5kqiA:
undetectable
5iy5T-5kqiA:
undetectable		 5iy5A-5kqiA:
20.60
5iy5B-5kqiA:
16.18
5iy5T-5kqiA:
8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 VAL A 524
LEU A 528
LEU A 521
GLY A 555
ALA A 484
 None
 1.11A 5jvzB-5kqiA:
1.1		 5jvzB-5kqiA:
21.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KSG_B_NIZB809_1
(CATALASE-PEROXIDASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		9 / 9 ARG A 123
GLU A 128
GLU A 198
VAL A 200
GLY A 493
SER A 494
GLN A 622
LEU A 623
THR A 625
 None
CL  A 803 ( 4.4A)
CL  A 803 (-4.8A)
None
None
None
None
None
None
 0.17A 5ksgB-5kqiA:
72.1		 5ksgB-5kqiA:
99.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KSN_A_NIZA809_1
(CATALASE-PEROXIDASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		9 / 9 ARG A 123
GLU A 128
GLU A 198
VAL A 200
GLY A 493
SER A 494
GLN A 622
LEU A 623
THR A 625
 None
CL  A 803 ( 4.4A)
CL  A 803 (-4.8A)
None
None
None
None
None
None
 0.14A 5ksnA-5kqiA:
73.2		 5ksnA-5kqiA:
99.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KSN_B_NIZB809_1
(CATALASE-PEROXIDASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		9 / 9 ARG A 123
GLU A 128
GLU A 198
VAL A 200
GLY A 493
SER A 494
GLN A 622
LEU A 623
THR A 625
 None
CL  A 803 ( 4.4A)
CL  A 803 (-4.8A)
None
None
None
None
None
None
 0.16A 5ksnB-5kqiA:
72.7		 5ksnB-5kqiA:
99.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KT8_B_NIZB809_1
(CATALASE-PEROXIDASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		9 / 9 ARG A 123
GLU A 128
GLU A 198
VAL A 200
GLY A 493
SER A 494
GLN A 622
LEU A 623
THR A 625
 None
CL  A 803 ( 4.4A)
CL  A 803 (-4.8A)
None
None
None
None
None
None
 0.15A 5kt8B-5kqiA:
72.7		 5kt8B-5kqiA:
99.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 GLY A 243
PRO A 244
THR A 387
SER A 391
 None
 0.94A 5ny7A-5kqiA:
undetectable		 5ny7A-5kqiA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OTR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 5 VAL A 251
ASP A 395
PRO A 396
ALA A 254
 None
 1.08A 5otrA-5kqiA:
undetectable		 5otrA-5kqiA:
19.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		6 / 8 ARG A 123
GLU A 128
GLU A 198
VAL A 200
GLN A 622
LEU A 623
 None
CL  A 803 ( 4.4A)
CL  A 803 (-4.8A)
None
None
None
 0.69A 5sxqB-5kqiA:
72.7		 5sxqB-5kqiA:
99.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		7 / 8 ARG A 123
GLU A 128
GLU A 198
VAL A 200
GLY A 493
LEU A 623
THR A 625
 None
CL  A 803 ( 4.4A)
CL  A 803 (-4.8A)
None
None
None
None
 0.17A 5sxqB-5kqiA:
72.7		 5sxqB-5kqiA:
99.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SXS_B_NIZB806_1
(CATALASE-PEROXIDASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		9 / 9 ARG A 123
GLU A 128
GLU A 198
VAL A 200
GLY A 493
SER A 494
GLN A 622
LEU A 623
THR A 625
 None
CL  A 803 ( 4.4A)
CL  A 803 (-4.8A)
None
None
None
None
None
None
 0.19A 5sxsB-5kqiA:
72.7		 5sxsB-5kqiA:
99.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SYI_B_NIZB805_1
(CATALASE-PEROXIDASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		9 / 9 ARG A 123
GLU A 128
GLU A 198
VAL A 200
GLY A 493
SER A 494
GLN A 622
LEU A 623
THR A 625
 None
CL  A 803 ( 4.4A)
CL  A 803 (-4.8A)
None
None
None
None
None
None
 0.16A 5syiB-5kqiA:
72.8		 5syiB-5kqiA:
99.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SYI_B_NIZB806_1
(CATALASE-PEROXIDASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 5 ARG A 108
HIS A 112
PRO A 241
SER A 324
 OXY  A 804 (-4.1A)
OXY  A 804 (-3.9A)
HEM  A 801 ( 4.3A)
HEM  A 801 (-2.6A)
 0.11A 5syiB-5kqiA:
72.8		 5syiB-5kqiA:
99.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		6 / 8 ARG A 123
GLU A 128
GLU A 198
VAL A 200
GLN A 622
LEU A 623
 None
CL  A 803 ( 4.4A)
CL  A 803 (-4.8A)
None
None
None
 0.64A 5syjA-5kqiA:
72.2		 5syjA-5kqiA:
99.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		7 / 8 ARG A 123
GLU A 128
GLU A 198
VAL A 200
GLY A 493
LEU A 623
THR A 625
 None
CL  A 803 ( 4.4A)
CL  A 803 (-4.8A)
None
None
None
None
 0.17A 5syjA-5kqiA:
72.2		 5syjA-5kqiA:
99.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SYJ_A_NIZA810_1
(CATALASE-PEROXIDASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 6 ARG A 108
HIS A 112
LEU A 236
PRO A 241
SER A 324
 OXY  A 804 (-4.1A)
OXY  A 804 (-3.9A)
None
HEM  A 801 ( 4.3A)
HEM  A 801 (-2.6A)
 0.11A 5syjA-5kqiA:
72.2		 5syjA-5kqiA:
99.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SYJ_B_NIZB810_1
(CATALASE-PEROXIDASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 6 ARG A 108
HIS A 112
LEU A 236
PRO A 241
SER A 324
 OXY  A 804 (-4.1A)
OXY  A 804 (-3.9A)
None
HEM  A 801 ( 4.3A)
HEM  A 801 (-2.6A)
 0.14A 5syjB-5kqiA:
71.7		 5syjB-5kqiA:
99.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 635
GLY A 636
GLY A 637
VAL A 640
LEU A 668
 None
 0.90A 5uc1A-5kqiA:
undetectable		 5uc1A-5kqiA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 641
LEU A 638
GLY A 637
GLY A 636
VAL A 633
 None
 1.05A 5uc1A-5kqiA:
undetectable		 5uc1A-5kqiA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 635
GLY A 636
GLY A 637
VAL A 640
LEU A 668
 None
 0.87A 5uc1B-5kqiA:
undetectable		 5uc1B-5kqiA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 641
LEU A 638
GLY A 637
GLY A 636
VAL A 633
 None
 1.05A 5uc1B-5kqiA:
undetectable		 5uc1B-5kqiA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.48A 5unrA-5kqiA:
undetectable
5unrB-5kqiA:
undetectable		 5unrA-5kqiA:
20.85
5unrB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.48A 5unuA-5kqiA:
1.5
5unuB-5kqiA:
undetectable		 5unuA-5kqiA:
20.85
5unuB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 VAL A 481
TRP A 736
PHE A 732
GLU A 560
 None
 1.49A 5unvA-5kqiA:
undetectable
5unvB-5kqiA:
undetectable		 5unvA-5kqiA:
20.85
5unvB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.47A 5unvA-5kqiA:
undetectable
5unvB-5kqiA:
undetectable		 5unvA-5kqiA:
20.85
5unvB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 6 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.48A 5unxA-5kqiA:
undetectable
5unxB-5kqiA:
undetectable		 5unxA-5kqiA:
20.85
5unxB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 5unzA-5kqiA:
undetectable
5unzB-5kqiA:
undetectable		 5unzA-5kqiA:
20.85
5unzB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.47A 5uo0A-5kqiA:
undetectable
5uo0B-5kqiA:
undetectable		 5uo0A-5kqiA:
20.85
5uo0B-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 VAL A 481
TRP A 736
PHE A 732
GLU A 560
 None
 1.49A 5uo2A-5kqiA:
undetectable
5uo2B-5kqiA:
undetectable		 5uo2A-5kqiA:
19.59
5uo2B-5kqiA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.50A 5uo4A-5kqiA:
1.3
5uo4B-5kqiA:
undetectable		 5uo4A-5kqiA:
19.59
5uo4B-5kqiA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 5uo7A-5kqiA:
undetectable
5uo7B-5kqiA:
1.6		 5uo7A-5kqiA:
19.59
5uo7B-5kqiA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.50A 5vuiA-5kqiA:
undetectable
5vuiB-5kqiA:
undetectable		 5vuiA-5kqiA:
20.85
5vuiB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 VAL A 481
TRP A 736
PHE A 732
GLU A 560
 None
 1.46A 5vujA-5kqiA:
undetectable
5vujB-5kqiA:
0.4		 5vujA-5kqiA:
20.85
5vujB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 5vujA-5kqiA:
undetectable
5vujB-5kqiA:
0.4		 5vujA-5kqiA:
20.85
5vujB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.48A 5vukA-5kqiA:
undetectable
5vukB-5kqiA:
undetectable		 5vukA-5kqiA:
20.85
5vukB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.50A 5vumA-5kqiA:
undetectable
5vumB-5kqiA:
undetectable		 5vumA-5kqiA:
20.85
5vumB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.50A 5vuoA-5kqiA:
undetectable
5vuoB-5kqiA:
undetectable		 5vuoA-5kqiA:
20.85
5vuoB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 5vuqA-5kqiA:
undetectable
5vuqB-5kqiA:
undetectable		 5vuqA-5kqiA:
20.85
5vuqB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.47A 5vurA-5kqiA:
undetectable
5vurB-5kqiA:
1.8		 5vurA-5kqiA:
20.85
5vurB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 5vusA-5kqiA:
undetectable
5vusB-5kqiA:
undetectable		 5vusA-5kqiA:
20.85
5vusB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 VAL A 481
TRP A 736
PHE A 732
GLU A 560
 None
 1.50A 5vutA-5kqiA:
undetectable
5vutB-5kqiA:
undetectable		 5vutA-5kqiA:
20.85
5vutB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 5vuuA-5kqiA:
undetectable
5vuuB-5kqiA:
undetectable		 5vuuA-5kqiA:
20.85
5vuuB-5kqiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 5vuyA-5kqiA:
undetectable
5vuyB-5kqiA:
undetectable		 5vuyA-5kqiA:
19.59
5vuyB-5kqiA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 5vv2A-5kqiA:
0.3
5vv2B-5kqiA:
undetectable		 5vv2A-5kqiA:
19.59
5vv2B-5kqiA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.47A 5vv5A-5kqiA:
1.6
5vv5B-5kqiA:
undetectable		 5vv5A-5kqiA:
19.59
5vv5B-5kqiA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 11 GLY A 104
THR A 333
THR A 331
PHE A 182
GLY A 277
 HEM  A 801 (-3.4A)
None
None
None
None
 1.48A 5w97A-5kqiA:
0.0
5w97B-5kqiA:
undetectable
5w97g-5kqiA:
undetectable		 5w97A-5kqiA:
20.60
5w97B-5kqiA:
16.18
5w97g-5kqiA:
8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 11 GLY A 104
THR A 333
THR A 331
PHE A 182
GLY A 277
 HEM  A 801 (-3.4A)
None
None
None
None
 1.48A 5x19A-5kqiA:
undetectable
5x19B-5kqiA:
undetectable
5x19T-5kqiA:
undetectable		 5x19A-5kqiA:
20.60
5x19B-5kqiA:
16.18
5x19T-5kqiA:
8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 10 GLY A 104
THR A 333
THR A 331
PHE A 182
GLY A 277
 HEM  A 801 (-3.4A)
None
None
None
None
 1.44A 5x1bA-5kqiA:
0.3
5x1bB-5kqiA:
undetectable
5x1bT-5kqiA:
undetectable		 5x1bA-5kqiA:
20.60
5x1bB-5kqiA:
16.18
5x1bT-5kqiA:
8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_O_CHDO302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 11 PHE A 182
GLY A 277
GLY A 104
THR A 333
THR A 331
 None
None
HEM  A 801 (-3.4A)
None
None
 1.48A 5x1bG-5kqiA:
undetectable
5x1bN-5kqiA:
0.4
5x1bO-5kqiA:
undetectable		 5x1bG-5kqiA:
8.52
5x1bN-5kqiA:
20.60
5x1bO-5kqiA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_G_CHDG102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 10 PHE A 182
GLY A 277
GLY A 104
THR A 333
THR A 331
 None
None
HEM  A 801 (-3.4A)
None
None
 1.44A 5xdqG-5kqiA:
undetectable
5xdqN-5kqiA:
0.0
5xdqO-5kqiA:
undetectable		 5xdqG-5kqiA:
8.52
5xdqN-5kqiA:
20.60
5xdqO-5kqiA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 11 GLY A 104
THR A 333
THR A 331
PHE A 182
GLY A 277
 HEM  A 801 (-3.4A)
None
None
None
None
 1.49A 5xdxA-5kqiA:
undetectable
5xdxB-5kqiA:
undetectable
5xdxT-5kqiA:
undetectable		 5xdxA-5kqiA:
20.60
5xdxB-5kqiA:
16.18
5xdxT-5kqiA:
8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_O_CHDO301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 10 PHE A 182
GLY A 277
GLY A 104
THR A 333
THR A 331
 None
None
HEM  A 801 (-3.4A)
None
None
 1.46A 5xdxG-5kqiA:
undetectable
5xdxN-5kqiA:
0.0
5xdxO-5kqiA:
undetectable		 5xdxG-5kqiA:
8.52
5xdxN-5kqiA:
20.60
5xdxO-5kqiA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.50A 6auqA-5kqiA:
undetectable
6auqB-5kqiA:
undetectable		 6auqA-5kqiA:
6.51
6auqB-5kqiA:
6.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.49A 6auuA-5kqiA:
undetectable
6auuB-5kqiA:
undetectable		 6auuA-5kqiA:
6.51
6auuB-5kqiA:
6.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.50A 6auwA-5kqiA:
1.5
6auwB-5kqiA:
undetectable		 6auwA-5kqiA:
6.51
6auwB-5kqiA:
6.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		4 / 7 TRP A 736
PHE A 732
GLU A 560
VAL A 481
 None
 1.48A 6av1A-5kqiA:
1.4
6av1B-5kqiA:
undetectable		 6av1A-5kqiA:
7.34
6av1B-5kqiA:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 9 ALA A 162
ILE A 163
PHE A 187
GLY A 436
PHE A  72
 None
 1.30A 6awoA-5kqiA:
2.5		 6awoA-5kqiA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 9 ALA A 162
ILE A 163
PHE A 187
GLY A 436
PHE A  72
 None
 1.31A 6awqA-5kqiA:
2.5		 6awqA-5kqiA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		3 / 3 ARG A 118
ARG A 610
ARG A 218
 None
 0.84A 6bplA-5kqiA:
2.8
6bplB-5kqiA:
undetectable		 6bplA-5kqiA:
7.30
6bplB-5kqiA:
7.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CDQ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		9 / 9 ARG A 123
GLU A 128
GLU A 198
VAL A 200
GLY A 493
SER A 494
GLN A 622
LEU A 623
THR A 625
 None
CL  A 803 ( 4.4A)
CL  A 803 (-4.8A)
None
None
None
None
None
None
 0.35A 6cdqA-5kqiA:
72.2		 6cdqA-5kqiA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CDQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		9 / 9 ARG A 123
GLU A 128
GLU A 198
VAL A 200
GLY A 493
SER A 494
GLN A 622
LEU A 623
THR A 625
 None
CL  A 803 ( 4.4A)
CL  A 803 (-4.8A)
None
None
None
None
None
None
 0.41A 6cdqB-5kqiA:
71.7		 6cdqB-5kqiA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CFQ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		9 / 9 ARG A 123
GLU A 128
GLU A 198
VAL A 200
GLY A 493
SER A 494
GLN A 622
LEU A 623
THR A 625
 None
CL  A 803 ( 4.4A)
CL  A 803 (-4.8A)
None
None
None
None
None
None
 0.14A 6cfqB-5kqiA:
72.8		 6cfqB-5kqiA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_B_CHDB304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5kqi CATALASE-PEROXIDASE
(Burkholderia
pseudomallei) 		5 / 11 GLY A 104
THR A 333
THR A 331
PHE A 182
GLY A 277
 HEM  A 801 (-3.4A)
None
None
None
None
 1.49A 6nknA-5kqiA:
undetectable
6nknB-5kqiA:
undetectable
6nknT-5kqiA:
undetectable		 6nknA-5kqiA:
20.60
6nknB-5kqiA:
16.18
6nknT-5kqiA:
8.52