SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ks1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 10 THR A 283
ALA A 123
ALA A 100
THR A  17
ILE A   6
 None
 1.18A 1gtnB-5ks1A:
undetectable
1gtnC-5ks1A:
undetectable		 1gtnB-5ks1A:
9.95
1gtnC-5ks1A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 10 THR A 283
ALA A 123
ALA A 100
THR A  17
ILE A   6
 None
 1.21A 1gtnH-5ks1A:
undetectable
1gtnI-5ks1A:
undetectable		 1gtnH-5ks1A:
9.95
1gtnI-5ks1A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 10 ALA A 100
THR A  17
ILE A   6
THR A 283
ALA A 123
 None
 1.20A 1gtnU-5ks1A:
undetectable
1gtnV-5ks1A:
undetectable		 1gtnU-5ks1A:
9.95
1gtnV-5ks1A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_1
(DNA GYRASE SUBUNIT B)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 12 ILE A 280
ASP A 275
ILE A  13
ALA A 100
THR A 283
 None
 1.17A 1kijB-5ks1A:
2.7		 1kijB-5ks1A:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		4 / 5 LEU A 379
VAL A 108
ALA A  89
CYH A  86
 None
 1.12A 1mz9D-5ks1A:
undetectable		 1mz9D-5ks1A:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1U_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 10 ILE A 280
LYS A  19
VAL A 294
GLY A 293
LEU A 284
 None
 1.46A 1s1uA-5ks1A:
undetectable		 1s1uA-5ks1A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_A_J01A1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 12 LEU A   7
ALA A  32
VAL A  55
ALA A  34
THR A  90
 None
 1.13A 2japA-5ks1A:
9.0		 2japA-5ks1A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_B_J01B1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 12 LEU A   7
ALA A  32
VAL A  55
ALA A  34
THR A  90
 None
 1.12A 2japB-5ks1A:
9.0		 2japB-5ks1A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_C_J01C1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 12 LEU A   7
ALA A  32
VAL A  55
ALA A  34
THR A  90
 None
 1.13A 2japC-5ks1A:
9.1		 2japC-5ks1A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_D_J01D1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 12 LEU A   7
ALA A  32
VAL A  55
ALA A  34
THR A  90
 None
 1.10A 2japD-5ks1A:
8.9		 2japD-5ks1A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LBD_A_REAA500_1
(RETINOIC ACID
RECEPTOR GAMMA)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 12 LEU A 121
ILE A 280
SER A 285
GLY A   8
LEU A  33
 None
 1.26A 2lbdA-5ks1A:
undetectable		 2lbdA-5ks1A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		4 / 7 GLY A   8
GLY A  11
THR A  17
ALA A 100
 None
 0.79A 3fpjB-5ks1A:
4.1		 3fpjB-5ks1A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 11 GLN A   2
VAL A 149
ALA A 123
THR A  17
ILE A  13
 None
 1.26A 3n23A-5ks1A:
undetectable		 3n23A-5ks1A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 12 TYR A 232
ALA A 324
TRP A 237
ASP A 361
LEU A 364
 None
 1.44A 3ou6D-5ks1A:
undetectable		 3ou6D-5ks1A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 12 LEU A 318
LYS A 247
LEU A 183
ALA A 235
ILE A 233
 None
 1.11A 3ut5B-5ks1A:
3.9		 3ut5B-5ks1A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_B_ADNB301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 9 LEU A 284
ILE A   6
LEU A  18
VAL A  20
THR A  17
 None
 1.16A 4x3mB-5ks1A:
2.3		 4x3mB-5ks1A:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJL_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 12 SER A 258
PHE A 312
LEU A 128
ASP A 150
GLU A 152
 None
None
None
MN  A 505 (-4.0A)
MN  A 505 ( 2.4A)
 1.36A 4zjlD-5ks1A:
2.6		 4zjlD-5ks1A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 10 THR A 283
ALA A 123
ALA A 100
THR A  17
ILE A   6
 None
 1.18A 5eeuF-5ks1A:
undetectable
5eeuG-5ks1A:
undetectable		 5eeuF-5ks1A:
9.95
5eeuG-5ks1A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 10 THR A 283
ALA A 123
ALA A 100
THR A  17
ILE A   6
 None
 1.18A 5eevF-5ks1A:
undetectable
5eevG-5ks1A:
undetectable		 5eevF-5ks1A:
9.95
5eevG-5ks1A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 10 THR A 283
ALA A 123
ALA A 100
THR A  17
ILE A   6
 None
 1.18A 5eewF-5ks1A:
undetectable
5eewG-5ks1A:
undetectable		 5eewF-5ks1A:
9.95
5eewG-5ks1A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 10 THR A 283
ALA A 123
ALA A 100
THR A  17
ILE A   6
 None
 1.18A 5eexF-5ks1A:
undetectable
5eexG-5ks1A:
undetectable		 5eexF-5ks1A:
9.95
5eexG-5ks1A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 10 THR A 283
ALA A 123
ALA A 100
THR A  17
ILE A   6
 None
 1.19A 5eeyF-5ks1A:
undetectable
5eeyG-5ks1A:
undetectable		 5eeyF-5ks1A:
9.95
5eeyG-5ks1A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 10 THR A 283
ALA A 123
ALA A 100
THR A  17
ILE A   6
 None
 1.18A 5eezF-5ks1A:
undetectable
5eezG-5ks1A:
undetectable		 5eezF-5ks1A:
9.95
5eezG-5ks1A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 10 THR A 283
ALA A 123
ALA A 100
THR A  17
ILE A   6
 None
 1.19A 5ef0F-5ks1A:
undetectable
5ef0G-5ks1A:
undetectable		 5ef0F-5ks1A:
9.95
5ef0G-5ks1A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 10 THR A 283
ALA A 123
ALA A 100
THR A  17
ILE A   6
 None
 1.19A 5ef1F-5ks1A:
undetectable
5ef1G-5ks1A:
undetectable		 5ef1F-5ks1A:
9.95
5ef1G-5ks1A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 10 THR A 283
ALA A 123
ALA A 100
THR A  17
ILE A   6
 None
 1.19A 5ef2F-5ks1A:
undetectable
5ef2G-5ks1A:
undetectable		 5ef2F-5ks1A:
9.95
5ef2G-5ks1A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 10 THR A 283
ALA A 123
ALA A 100
THR A  17
ILE A   6
 None
 1.19A 5ef3F-5ks1A:
undetectable
5ef3G-5ks1A:
undetectable		 5ef3F-5ks1A:
9.95
5ef3G-5ks1A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		4 / 7 LEU A 383
ASP A 386
ALA A 389
LEU A 392
 None
 1.02A 5nwvA-5ks1A:
undetectable		 5nwvA-5ks1A:
6.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		4 / 8 HIS A 180
VAL A 260
LEU A 173
ALA A 241
 None
 0.88A 5tt3H-5ks1A:
undetectable		 5tt3H-5ks1A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_0
(REGULATORY PROTEIN
TETR)		 5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Vibrio
vulnificus) 		5 / 12 ALA A 337
GLU A 384
LEU A 382
VAL A 367
CYH A 368
 None
 1.45A 5vlmH-5ks1A:
2.5		 5vlmH-5ks1A:
19.60