SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ks5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 5ks5 EUKARYOTIC
ELONGATION FACTOR 2
KINASE
(Homo
sapiens) 		3 / 3 TRP A 720
GLU A 717
TYR A 713
 None
 1.08A 2a3aA-5ks5A:
undetectable		 2a3aA-5ks5A:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 5ks5 EUKARYOTIC
ELONGATION FACTOR 2
KINASE
(Homo
sapiens) 		4 / 5 TYR A 693
THR A 694
ARG A 688
LEU A 675
 None
 1.34A 3qelC-5ks5A:
undetectable		 3qelC-5ks5A:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5ks5 EUKARYOTIC
ELONGATION FACTOR 2
KINASE
(Homo
sapiens) 		3 / 3 TYR A 641
ALA A 716
TYR A 713
 None
 0.87A 5uunB-5ks5A:
undetectable		 5uunB-5ks5A:
19.37