SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kss'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UUJ_B_ACTB1077_0
(PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT)		 5kss 5'-NUCLEOTIDASE SURE
(Xylella
fastidiosa) 		3 / 3 ARG A 176
TYR A 228
LYS A 179
 None
 0.97A 1uujB-5kssA:
undetectable		 1uujB-5kssA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_1
(FIV PROTEASE)		 5kss 5'-NUCLEOTIDASE SURE
(Xylella
fastidiosa) 		5 / 10 LEU A 125
ALA A 144
ILE A 148
VAL A 165
GLY A 177
 None
 0.94A 3ogqA-5kssA:
undetectable		 3ogqA-5kssA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 5kss 5'-NUCLEOTIDASE SURE
(Xylella
fastidiosa) 		4 / 7 ASN A   7
ALA A  34
PRO A  35
ALA A 109
 None
 1.13A 3twpA-5kssA:
4.1		 3twpA-5kssA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 5kss 5'-NUCLEOTIDASE SURE
(Xylella
fastidiosa) 		4 / 7 ASN A   7
ALA A  34
PRO A  35
ALA A 109
 None
 1.11A 3twpB-5kssA:
3.5		 3twpB-5kssA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 5kss 5'-NUCLEOTIDASE SURE
(Xylella
fastidiosa) 		4 / 7 ASN A   7
ALA A  34
PRO A  35
ALA A 109
 None
 1.11A 3twpC-5kssA:
4.1		 3twpC-5kssA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 5kss 5'-NUCLEOTIDASE SURE
(Xylella
fastidiosa) 		4 / 5 ASN A   7
ALA A  34
PRO A  35
ALA A 109
 None
 1.12A 3twpD-5kssA:
3.5		 3twpD-5kssA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_A_RKEA401_1
(PROTON-GATED ION
CHANNEL)		 5kss 5'-NUCLEOTIDASE SURE
(Xylella
fastidiosa) 		4 / 8 ASN A   7
ASP A   9
VAL A  32
LEU A  19
 None
MN  A 501 (-3.1A)
None
None
 1.08A 4f8hA-5kssA:
undetectable
4f8hB-5kssA:
undetectable		 4f8hA-5kssA:
21.92
4f8hB-5kssA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_C_RKEC401_1
(PROTON-GATED ION
CHANNEL)		 5kss 5'-NUCLEOTIDASE SURE
(Xylella
fastidiosa) 		4 / 8 ASN A   7
ASP A   9
VAL A  32
LEU A  19
 None
MN  A 501 (-3.1A)
None
None
 1.08A 4f8hC-5kssA:
undetectable
4f8hD-5kssA:
undetectable		 4f8hC-5kssA:
21.92
4f8hD-5kssA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_D_RKED401_1
(PROTON-GATED ION
CHANNEL)		 5kss 5'-NUCLEOTIDASE SURE
(Xylella
fastidiosa) 		4 / 8 ASN A   7
ASP A   9
VAL A  32
LEU A  19
 None
MN  A 501 (-3.1A)
None
None
 1.09A 4f8hD-5kssA:
undetectable
4f8hE-5kssA:
undetectable		 4f8hD-5kssA:
21.92
4f8hE-5kssA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_E_RKEE401_1
(PROTON-GATED ION
CHANNEL)		 5kss 5'-NUCLEOTIDASE SURE
(Xylella
fastidiosa) 		4 / 8 VAL A  32
LEU A  19
ASN A   7
ASP A   9
 None
None
None
MN  A 501 (-3.1A)
 1.11A 4f8hA-5kssA:
undetectable
4f8hE-5kssA:
undetectable		 4f8hA-5kssA:
21.92
4f8hE-5kssA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5kss 5'-NUCLEOTIDASE SURE
(Xylella
fastidiosa) 		5 / 12 GLY A 105
THR A  69
THR A  77
GLY A 113
LEU A 116
 CL  A 504 ( 4.9A)
None
None
None
None
 1.16A 4n48A-5kssA:
undetectable		 4n48A-5kssA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5kss 5'-NUCLEOTIDASE SURE
(Xylella
fastidiosa) 		5 / 12 GLY A 105
THR A  69
THR A  77
GLY A 113
LEU A 116
 CL  A 504 ( 4.9A)
None
None
None
None
 1.15A 4n48B-5kssA:
undetectable		 4n48B-5kssA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5kss 5'-NUCLEOTIDASE SURE
(Xylella
fastidiosa) 		4 / 6 ASP A 222
LYS A 179
THR A 219
THR A 181
 None
 1.43A 4z4fA-5kssA:
3.9		 4z4fA-5kssA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 5kss 5'-NUCLEOTIDASE SURE
(Xylella
fastidiosa) 		4 / 7 GLY A  15
GLY A  90
SER A  89
ASP A   9
 None
None
None
MN  A 501 (-3.1A)
 0.73A 5ergB-5kssA:
2.4		 5ergB-5kssA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 5kss 5'-NUCLEOTIDASE SURE
(Xylella
fastidiosa) 		5 / 10 PRO A 156
ILE A 146
ALA A  22
VAL A   3
PRO A 119
 None
 1.30A 5m0oA-5kssA:
undetectable		 5m0oA-5kssA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V1S_A_SAMA604_0
(RADICAL SAM)		 5kss 5'-NUCLEOTIDASE SURE
(Xylella
fastidiosa) 		5 / 9 LEU A 183
THR A 232
SER A 230
ASN A 166
VAL A 126
 None
 1.16A 5v1sA-5kssA:
undetectable		 5v1sA-5kssA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V1T_A_SAMA605_0
(RADICAL SAM)		 5kss 5'-NUCLEOTIDASE SURE
(Xylella
fastidiosa) 		5 / 12 LEU A 183
THR A 232
SER A 230
ASN A 166
VAL A 126
 None
 1.27A 5v1tA-5kssA:
undetectable		 5v1tA-5kssA:
17.44