SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kta'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VPO_H_TESH1010_1 (ANTI-TESTOSTERONE (HEAVY CHAIN) ANTI-TESTOSTERONE (LIGHT CHAIN))	5kta	FDHC (Acinetobacter nosocomialis)	5 / 12	TYR A 65 ALA A 118 GLY A 119 LEU A 123 PHE A 85	DMS A 204 (-4.5A) None None None None	1.17A	1vpoH-5ktaA: undetectable 1vpoL-5ktaA: undetectable	1vpoH-5ktaA: 20.09 1vpoL-5ktaA: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZLQ_B_EDTB1511_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	5kta	FDHC (Acinetobacter nosocomialis)	4 / 8	TRP A 50 ARG A 28 TYR A 65 THR A 79	DMS A 204 (-3.4A) SO4 A 202 (-3.1A) DMS A 204 (-4.5A) None	1.19A	1zlqB-5ktaA: undetectable	1zlqB-5ktaA: 17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KVR_A_URFA2001_1 (URIDINE PHOSPHORYLASE)	5kta	FDHC (Acinetobacter nosocomialis)	5 / 10	THR A 122 GLY A 119 PHE A 66 GLU A 117 LEU A 123	None	1.27A	3kvrA-5ktaA: undetectable	3kvrA-5ktaA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KVR_B_URFB2011_1 (URIDINE PHOSPHORYLASE)	5kta	FDHC (Acinetobacter nosocomialis)	5 / 10	THR A 122 GLY A 119 PHE A 66 GLU A 117 LEU A 123	None	1.26A	3kvrB-5ktaA: undetectable	3kvrB-5ktaA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L8D_A_EDTA609_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	5kta	FDHC (Acinetobacter nosocomialis)	4 / 8	TRP A 50 ARG A 28 TYR A 65 THR A 79	DMS A 204 (-3.4A) SO4 A 202 (-3.1A) DMS A 204 (-4.5A) None	1.26A	5l8dA-5ktaA: 0.3	5l8dA-5ktaA: 17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWU_A_EDTA609_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	5kta	FDHC (Acinetobacter nosocomialis)	4 / 8	TRP A 50 ARG A 28 TYR A 65 THR A 79	DMS A 204 (-3.4A) SO4 A 202 (-3.1A) DMS A 204 (-4.5A) None	1.26A	5mwuA-5ktaA: 0.3	5mwuA-5ktaA: 17.72

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1VPO_H_TESH1010_1","ANTI-TESTOSTERONE (HEAVY CHAIN);ANTI-TESTOSTERONE (LIGHT CHAIN)","5kta","FDHC","Acinetobacter nosocomialis",5,"TYR A  65;ALA A 118;GLY A 119;LEU A 123;PHE A  85","DMS A 204 (-4.5A);None;None;None;None","1.17A","1vpoH-5ktaA:undetectable;1vpoL-5ktaA:undetectable","1vpoH-5ktaA:20.09;1vpoL-5ktaA:20.61"],["1ZLQ_B_EDTB1511_0","NICKEL-BINDING PERIPLASMIC PROTEIN","5kta","FDHC","Acinetobacter nosocomialis",4,"TRP A  50;ARG A  28;TYR A  65;THR A  79","DMS A 204 (-3.4A);SO4 A 202 (-3.1A);DMS A 204 (-4.5A);None","1.19A","1zlqB-5ktaA:undetectable","1zlqB-5ktaA:17.72"],["3KVR_A_URFA2001_1","URIDINE PHOSPHORYLASE","5kta","FDHC","Acinetobacter nosocomialis",5,"THR A 122;GLY A 119;PHE A  66;GLU A 117;LEU A 123","None","1.27A","3kvrA-5ktaA:undetectable","3kvrA-5ktaA:18.33"],["3KVR_B_URFB2011_1","URIDINE PHOSPHORYLASE","5kta","FDHC","Acinetobacter nosocomialis",5,"THR A 122;GLY A 119;PHE A  66;GLU A 117;LEU A 123","None","1.26A","3kvrB-5ktaA:undetectable","3kvrB-5ktaA:18.33"],["5L8D_A_EDTA609_0","NICKEL-BINDING PERIPLASMIC PROTEIN","5kta","FDHC","Acinetobacter nosocomialis",4,"TRP A  50;ARG A  28;TYR A  65;THR A  79","DMS A 204 (-3.4A);SO4 A 202 (-3.1A);DMS A 204 (-4.5A);None","1.26A","5l8dA-5ktaA:0.3","5l8dA-5ktaA:17.72"],["5MWU_A_EDTA609_0","NICKEL-BINDING PERIPLASMIC PROTEIN","5kta","FDHC","Acinetobacter nosocomialis",4,"TRP A  50;ARG A  28;TYR A  65;THR A  79","DMS A 204 (-3.4A);SO4 A 202 (-3.1A);DMS A 204 (-4.5A);None","1.26A","5mwuA-5ktaA:0.3","5mwuA-5ktaA:17.72"]]