SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ktg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 5ktg GREEN FLUORESCENT
PROTEIN, BCL-2
HOMOLOGOUS
ANTAGONIST/KILLER
(Aequorea
victoria;
Mus
musculus) 		4 / 7 HIS A 181
LEU A  60
THR A  62
THR A  63
 None
 1.00A 1am6A-5ktgA:
undetectable		 1am6A-5ktgA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 5ktg GREEN FLUORESCENT
PROTEIN, BCL-2
HOMOLOGOUS
ANTAGONIST/KILLER
(Aequorea
victoria;
Mus
musculus) 		3 / 3 THR A  62
PRO A  58
TYR A 145
 None
None
CR2  A  66 ( 4.1A)
 0.94A 2dxrA-5ktgA:
undetectable		 2dxrA-5ktgA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 5ktg GREEN FLUORESCENT
PROTEIN, BCL-2
HOMOLOGOUS
ANTAGONIST/KILLER
(Aequorea
victoria;
Mus
musculus) 		5 / 10 HIS A 181
PHE A  27
LEU A  60
THR A  62
THR A  63
 None
 1.45A 3dazA-5ktgA:
undetectable		 3dazA-5ktgA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 5ktg GREEN FLUORESCENT
PROTEIN, BCL-2
HOMOLOGOUS
ANTAGONIST/KILLER
(Aequorea
victoria;
Mus
musculus) 		5 / 10 HIS A 181
PHE A  27
LEU A  60
THR A  62
THR A  63
 None
 1.46A 3dcsA-5ktgA:
undetectable		 3dcsA-5ktgA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)		 5ktg GREEN FLUORESCENT
PROTEIN, BCL-2
HOMOLOGOUS
ANTAGONIST/KILLER
(Aequorea
victoria;
Mus
musculus) 		5 / 11 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
None
CR2  A  66 ( 4.1A)
None
None
 1.17A 3t3rA-5ktgA:
undetectable		 3t3rA-5ktgA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 5ktg GREEN FLUORESCENT
PROTEIN, BCL-2
HOMOLOGOUS
ANTAGONIST/KILLER
(Aequorea
victoria;
Mus
musculus) 		5 / 9 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
None
CR2  A  66 ( 4.1A)
None
None
 1.15A 3t3rB-5ktgA:
undetectable		 3t3rB-5ktgA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 5ktg GREEN FLUORESCENT
PROTEIN, BCL-2
HOMOLOGOUS
ANTAGONIST/KILLER
(Aequorea
victoria;
Mus
musculus) 		5 / 9 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
None
CR2  A  66 ( 4.1A)
None
None
 1.17A 3t3rC-5ktgA:
undetectable		 3t3rC-5ktgA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 5ktg GREEN FLUORESCENT
PROTEIN, BCL-2
HOMOLOGOUS
ANTAGONIST/KILLER
(Aequorea
victoria;
Mus
musculus) 		5 / 10 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
None
CR2  A  66 ( 4.1A)
None
None
 1.13A 3t3rD-5ktgA:
undetectable		 3t3rD-5ktgA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 5ktg GREEN FLUORESCENT
PROTEIN, BCL-2
HOMOLOGOUS
ANTAGONIST/KILLER
(Aequorea
victoria;
Mus
musculus) 		5 / 10 HIS A 181
PHE A  27
LEU A  60
THR A  62
THR A  63
 None
 1.40A 3v2mA-5ktgA:
undetectable		 3v2mA-5ktgA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 5ktg GREEN FLUORESCENT
PROTEIN, BCL-2
HOMOLOGOUS
ANTAGONIST/KILLER
(Aequorea
victoria;
Mus
musculus) 		4 / 6 ARG A1135
LEU A1136
ALA A1105
GLN A1092
 None
 1.01A 6b89B-5ktgA:
undetectable		 6b89B-5ktgA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 5ktg GREEN FLUORESCENT
PROTEIN, BCL-2
HOMOLOGOUS
ANTAGONIST/KILLER
(Aequorea
victoria;
Mus
musculus) 		5 / 12 HIS A 148
ILE A 161
PHE A  84
THR A  63
THR A  62
 CR2  A  66 ( 3.9A)
None
None
None
None
 1.21A 6bbsA-5ktgA:
undetectable		 6bbsA-5ktgA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_0
(NS3 PROTEASE)		 5ktg GREEN FLUORESCENT
PROTEIN, BCL-2
HOMOLOGOUS
ANTAGONIST/KILLER
(Aequorea
victoria;
Mus
musculus) 		5 / 12 GLY A 134
ARG A 168
ILE A  98
GLY A 104
ALA A 179
 None
 1.07A 6c2mD-5ktgA:
undetectable		 6c2mD-5ktgA:
14.24