SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ktz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 5ktz VP1
(Enterovirus
C) 		4 / 8 TYR 1 159
ILE 1 110
GLY 1 238
PHE 1 130
 None
 0.85A 2vctB-5ktz1:
undetectable		 2vctB-5ktz1:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_D_ASDD1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 5ktz VP1
(Enterovirus
C) 		4 / 7 TYR 1 159
ILE 1 110
GLY 1 238
PHE 1 130
 None
 0.86A 2vctD-5ktz1:
undetectable		 2vctD-5ktz1:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)		 5ktz VHH 12B
(Camelus
dromedarius) 		4 / 8 MET 7  83
PHE 7  68
GLY 7  66
GLY 7  47
 None
 0.94A 2y6rB-5ktz7:
undetectable		 2y6rB-5ktz7:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5ktz VP1
(Enterovirus
C) 		4 / 5 ILE 1 157
ARG 1 258
MET 1  90
THR 1  91
 None
 1.13A 3abkN-5ktz1:
undetectable
3abkW-5ktz1:
undetectable		 3abkN-5ktz1:
15.79
3abkW-5ktz1:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5ktz VP1
(Enterovirus
C) 		4 / 4 LEU 1 261
PRO 1 263
LEU 1 118
ARG 1 119
 None
 1.36A 3hcoB-5ktz1:
undetectable		 3hcoB-5ktz1:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7V_A_SAMA992_0
(METHYLORNITHINE
SYNTHASE PYLB)		 5ktz VHH 12B
(Camelus
dromedarius) 		5 / 12 GLY 7  10
GLY 7   8
GLN 7  13
VAL 7 120
ALA 7  14
 None
 1.26A 3t7vA-5ktz7:
undetectable		 3t7vA-5ktz7:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5ktz VP1
(Enterovirus
C) 		4 / 6 ASP 1 171
GLU 1 168
VAL 1 107
ALA 1 106
 None
 1.01A 4nkxA-5ktz1:
undetectable		 4nkxA-5ktz1:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_1
(CYP51 VARIANT1)		 5ktz VHH 12B
(Camelus
dromedarius) 		5 / 12 GLY 7  15
GLN 7  13
LEU 7  20
GLY 7 115
PHE 7  68
 None
 1.24A 5fsaB-5ktz7:
undetectable		 5fsaB-5ktz7:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 5ktz VP1
(Enterovirus
C) 		5 / 12 HIS 1 248
SER 1 182
GLN 1 156
ASP 1 171
ASP 1 172
 None
 1.34A 6bxnA-5ktz1:
undetectable		 6bxnA-5ktz1:
18.69