SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ku7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_1
(CES1 PROTEIN)		 5ku7 TIR-NB-LRR TYPE
RESISTANCE PROTEIN
RPV1
(Vitis
rotundifolia) 		5 / 12 SER A  80
LEU A  71
LEU A  70
LEU A 108
HIS A 110
 None
 1.28A 1ya4B-5ku7A:
undetectable		 1ya4B-5ku7A:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X9G_A_LYAA1270_1
(PTERIDINE REDUCTASE)		 5ku7 TIR-NB-LRR TYPE
RESISTANCE PROTEIN
RPV1
(Vitis
rotundifolia) 		5 / 12 SER A  29
PHE A  84
TYR A  88
LEU A 159
PRO A 114
 None
 1.47A 2x9gA-5ku7A:
5.5		 2x9gA-5ku7A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X9G_C_LYAC1270_1
(PTERIDINE REDUCTASE)		 5ku7 TIR-NB-LRR TYPE
RESISTANCE PROTEIN
RPV1
(Vitis
rotundifolia) 		5 / 12 SER A  29
PHE A  84
TYR A  88
LEU A 159
PRO A 114
 None
 1.49A 2x9gC-5ku7A:
6.0		 2x9gC-5ku7A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X9G_D_LYAD1270_1
(PTERIDINE REDUCTASE)		 5ku7 TIR-NB-LRR TYPE
RESISTANCE PROTEIN
RPV1
(Vitis
rotundifolia) 		5 / 12 SER A  29
PHE A  84
TYR A  88
LEU A 159
PRO A 114
 None
 1.49A 2x9gD-5ku7A:
3.8		 2x9gD-5ku7A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BMC_C_FOLC270_0
(PTERIDINE REDUCTASE)		 5ku7 TIR-NB-LRR TYPE
RESISTANCE PROTEIN
RPV1
(Vitis
rotundifolia) 		5 / 12 SER A  29
PHE A  84
TYR A  88
LEU A 159
PRO A 114
 None
 1.43A 3bmcC-5ku7A:
5.8		 3bmcC-5ku7A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_A_DX4A270_0
(PTERIDINE REDUCTASE
1)		 5ku7 TIR-NB-LRR TYPE
RESISTANCE PROTEIN
RPV1
(Vitis
rotundifolia) 		4 / 6 SER A  29
PHE A  84
TYR A  88
PRO A 114
 None
 1.50A 3jqaA-5ku7A:
5.7		 3jqaA-5ku7A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_C_DX4C270_0
(PTERIDINE REDUCTASE
1)		 5ku7 TIR-NB-LRR TYPE
RESISTANCE PROTEIN
RPV1
(Vitis
rotundifolia) 		4 / 6 SER A  29
PHE A  84
TYR A  88
PRO A 114
 None
 1.47A 3jqaC-5ku7A:
6.0		 3jqaC-5ku7A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_D_DX4D270_0
(PTERIDINE REDUCTASE
1)		 5ku7 TIR-NB-LRR TYPE
RESISTANCE PROTEIN
RPV1
(Vitis
rotundifolia) 		4 / 6 SER A  29
PHE A  84
TYR A  88
PRO A 114
 None
 1.48A 3jqaD-5ku7A:
6.2		 3jqaD-5ku7A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5ku7 TIR-NB-LRR TYPE
RESISTANCE PROTEIN
RPV1
(Vitis
rotundifolia) 		4 / 5 ALA A 136
TYR A 138
GLY A 161
LEU A  98
 None
 0.81A 5eslA-5ku7A:
undetectable		 5eslA-5ku7A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNX_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 5ku7 TIR-NB-LRR TYPE
RESISTANCE PROTEIN
RPV1
(Vitis
rotundifolia) 		5 / 12 VAL A 119
GLU A  86
LEU A 153
SER A 130
LEU A  95
 None
 1.34A 5hnxB-5ku7A:
undetectable		 5hnxB-5ku7A:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JDC_A_6JPA302_1
(PTERIDINE REDUCTASE)		 5ku7 TIR-NB-LRR TYPE
RESISTANCE PROTEIN
RPV1
(Vitis
rotundifolia) 		5 / 10 SER A  29
PHE A  84
TYR A  88
LEU A 159
PRO A 114
 None
 1.42A 5jdcA-5ku7A:
5.8
5jdcD-5ku7A:
6.2		 5jdcA-5ku7A:
20.79
5jdcD-5ku7A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JDC_C_6JPC302_1
(PTERIDINE REDUCTASE)		 5ku7 TIR-NB-LRR TYPE
RESISTANCE PROTEIN
RPV1
(Vitis
rotundifolia) 		5 / 10 SER A  29
PHE A  84
TYR A  88
LEU A 159
PRO A 114
 None
 1.40A 5jdcB-5ku7A:
4.3
5jdcC-5ku7A:
6.0		 5jdcB-5ku7A:
20.79
5jdcC-5ku7A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JDC_D_6JPD302_1
(PTERIDINE REDUCTASE)		 5ku7 TIR-NB-LRR TYPE
RESISTANCE PROTEIN
RPV1
(Vitis
rotundifolia) 		5 / 11 SER A  29
PHE A  84
TYR A  88
LEU A 159
PRO A 114
 None
 1.42A 5jdcA-5ku7A:
5.8
5jdcD-5ku7A:
6.2		 5jdcA-5ku7A:
20.79
5jdcD-5ku7A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 5ku7 TIR-NB-LRR TYPE
RESISTANCE PROTEIN
RPV1
(Vitis
rotundifolia) 		4 / 6 ARG A  31
ARG A  92
LEU A  95
ASP A  96
 MLA  A 201 (-2.7A)
None
None
None
 1.08A 5tdzA-5ku7A:
4.6		 5tdzA-5ku7A:
17.63