SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kvc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 5kvc HALOHYDRIN
DEHALOGENASE
(Agrobacterium
tumefaciens) 		4 / 6 LEU A 178
GLY A  13
SER A  17
ILE A 173
 CL  A 301 (-4.3A)
EDO  A 305 ( 4.3A)
None
None
 0.93A 1yajF-5kvcA:
undetectable		 1yajF-5kvcA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 5kvc HALOHYDRIN
DEHALOGENASE
(Agrobacterium
tumefaciens) 		4 / 7 SER A  34
ASP A  32
ARG A 107
GLU A  58
 None
 0.99A 2cdqB-5kvcA:
undetectable		 2cdqB-5kvcA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 5kvc HALOHYDRIN
DEHALOGENASE
(Agrobacterium
tumefaciens) 		5 / 12 ALA A  18
GLY A  13
GLY A 218
ASN A  79
VAL A   6
 None
EDO  A 305 ( 4.3A)
None
None
None
 1.20A 3f8wC-5kvcA:
2.2		 3f8wC-5kvcA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5kvc HALOHYDRIN
DEHALOGENASE
(Agrobacterium
tumefaciens) 		5 / 12 GLY A 151
ILE A 236
ASN A 157
GLY A 174
SER A 147
 None
 0.99A 4obwC-5kvcA:
5.3		 4obwC-5kvcA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_A_010A609_0
(HNL ISOENZYME 5)		 5kvc HALOHYDRIN
DEHALOGENASE
(Agrobacterium
tumefaciens) 		5 / 11 ALA A 225
VAL A  75
LEU A 217
VAL A  77
HIS A  26
 None
 1.18A 5eb5A-5kvcA:
2.9		 5eb5A-5kvcA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_B_010B607_0
(HNL ISOENZYME 5)		 5kvc HALOHYDRIN
DEHALOGENASE
(Agrobacterium
tumefaciens) 		5 / 10 ALA A 225
VAL A  75
LEU A 217
VAL A  77
HIS A  26
 None
 1.19A 5eb5B-5kvcA:
3.0		 5eb5B-5kvcA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V1T_A_SAMA605_0
(RADICAL SAM)		 5kvc HALOHYDRIN
DEHALOGENASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 155
SER A  78
TYR A 145
THR A 134
GLU A 102
 None
None
IMD  A 302 (-4.5A)
IMD  A 302 (-4.0A)
EDO  A 308 (-3.5A)
 1.30A 5v1tA-5kvcA:
undetectable		 5v1tA-5kvcA:
20.88