SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kw9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 5kw9 IGA(VH)-IGG(CH)
HEAVY CHAIN FAB
FRAGMENT
(Homo
sapiens) 		3 / 3 VAL H  20
VAL H  83
TRP H  36
 None
 0.78A 1av2C-5kw9H:
undetectable
1av2D-5kw9H:
undetectable		 1av2C-5kw9H:
5.26
1av2D-5kw9H:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 5kw9 IGA(VH)-IGG(CH)
HEAVY CHAIN FAB
FRAGMENT
(Homo
sapiens) 		3 / 3 VAL H  20
VAL H  83
TRP H  36
 None
 0.84A 1w5uC-5kw9H:
undetectable
1w5uD-5kw9H:
undetectable		 1w5uC-5kw9H:
5.26
1w5uD-5kw9H:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5kw9 IGA(VH)-IGG(CH)
HEAVY CHAIN FAB
FRAGMENT
(Homo
sapiens) 		4 / 6 LEU H 200
GLY H 201
ALA H 136
PRO H 137
 None
 0.50A 3huoA-5kw9H:
undetectable		 3huoA-5kw9H:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB8_0
(GRAMICIDIN D)		 5kw9 IGA(VH)-IGG(CH)
HEAVY CHAIN FAB
FRAGMENT
(Homo
sapiens) 		3 / 3 VAL H  20
VAL H  83
TRP H  36
 None
 0.77A 3l8lA-5kw9H:
undetectable
3l8lB-5kw9H:
undetectable		 3l8lA-5kw9H:
5.26
3l8lB-5kw9H:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 5kw9 IGA(VH)-IGG(CH)
HEAVY CHAIN FAB
FRAGMENT
(Homo
sapiens) 		3 / 3 VAL H  20
VAL H  83
TRP H  36
 None
 0.88A 3l8lC-5kw9H:
undetectable
3l8lD-5kw9H:
undetectable		 3l8lC-5kw9H:
5.26
3l8lD-5kw9H:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 5kw9 IGA(VH)-IGG(CH)
HEAVY CHAIN FAB
FRAGMENT
(Homo
sapiens) 		6 / 12 VAL H 195
THR H 146
LEU H 170
VAL H 174
GLY H 173
VAL H 222
 None
 1.46A 6a94B-5kw9H:
undetectable		 6a94B-5kw9H:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)		 5kw9 IGA(VH)-IGG(CH)
HEAVY CHAIN FAB
FRAGMENT
(Homo
sapiens) 		3 / 3 PRO H 196
SER H 198
SER H 199
 None
 0.56A 6bpyA-5kw9H:
undetectable		 6bpyA-5kw9H:
21.35