SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kyo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		5 / 11 VAL A 249
GLY A 250
THR A 254
VAL A 297
VAL A 398
 None
HEM  A 501 (-3.8A)
HEM  A 501 (-3.5A)
HEM  A 501 (-4.3A)
None
 0.81A 1akdA-5kyoA:
50.1		 1akdA-5kyoA:
40.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		5 / 11 VAL A 249
GLY A 251
THR A 254
VAL A 297
VAL A 398
 None
HEM  A 501 (-3.3A)
HEM  A 501 (-3.5A)
HEM  A 501 (-4.3A)
None
 0.93A 1akdA-5kyoA:
50.1		 1akdA-5kyoA:
40.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		6 / 11 VAL A 249
GLY A 250
THR A 254
VAL A 297
ILE A 397
VAL A 398
 None
HEM  A 501 (-3.8A)
HEM  A 501 (-3.5A)
HEM  A 501 (-4.3A)
None
None
 0.98A 1phgA-5kyoA:
50.4		 1phgA-5kyoA:
40.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		6 / 11 VAL A 249
GLY A 251
THR A 254
VAL A 297
ILE A 397
VAL A 398
 None
HEM  A 501 (-3.3A)
HEM  A 501 (-3.5A)
HEM  A 501 (-4.3A)
None
None
 1.00A 1phgA-5kyoA:
50.4		 1phgA-5kyoA:
40.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		4 / 6 MET A 369
VAL A 372
LEU A 373
PHE A 377
 None
 0.66A 1x8vA-5kyoA:
27.9		 1x8vA-5kyoA:
25.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A1M_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		5 / 8 VAL A 249
GLY A 250
THR A 254
VAL A 297
ILE A 397
 None
HEM  A 501 (-3.8A)
HEM  A 501 (-3.5A)
HEM  A 501 (-4.3A)
None
 0.56A 2a1mB-5kyoA:
50.3		 2a1mB-5kyoA:
40.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		5 / 11 VAL A 249
GLY A 250
THR A 254
VAL A 297
VAL A 398
 None
HEM  A 501 (-3.8A)
HEM  A 501 (-3.5A)
HEM  A 501 (-4.3A)
None
 0.75A 2a1nA-5kyoA:
50.2		 2a1nA-5kyoA:
40.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		5 / 11 VAL A 249
GLY A 251
THR A 254
VAL A 297
VAL A 398
 None
HEM  A 501 (-3.3A)
HEM  A 501 (-3.5A)
HEM  A 501 (-4.3A)
None
 0.94A 2a1nA-5kyoA:
50.2		 2a1nA-5kyoA:
40.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_A_H4BA1290_1
(PTERIDINE REDUCTASE
1)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		4 / 8 ARG A 347
PHE A 290
LEU A 266
LEU A 342
 None
 0.97A 2bfpA-5kyoA:
undetectable		 2bfpA-5kyoA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		5 / 12 LEU A 259
LEU A 160
GLY A 251
CYH A 359
ALA A 362
 None
None
HEM  A 501 (-3.3A)
HEM  A 501 (-2.4A)
None
 1.19A 2bm9C-5kyoA:
undetectable		 2bm9C-5kyoA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_C_TPFC2471_1
(CYTOCHROME P450 121)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		4 / 8 THR A 262
VAL A 256
PHE A 291
ALA A 365
 None
None
HEM  A 501 (-4.8A)
HEM  A 501 (-3.5A)
 1.18A 2ij7C-5kyoA:
35.2		 2ij7C-5kyoA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNJ_A_225A501_1
(CYTOCHROME P450 2C8)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		5 / 10 VAL A 249
THR A 254
VAL A 297
ILE A 397
VAL A 398
 None
HEM  A 501 (-3.5A)
HEM  A 501 (-4.3A)
None
None
 0.72A 2nnjA-5kyoA:
30.2		 2nnjA-5kyoA:
23.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		4 / 7 LEU A 195
VAL A 198
THR A 199
VAL A 249
 None
 0.85A 2qblA-5kyoA:
50.0		 2qblA-5kyoA:
40.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA802_1
(TRANSPORTER)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		4 / 6 ARG A 145
PHE A 144
ILE A 141
PHE A 156
 None
 1.29A 2qeiA-5kyoA:
undetectable		 2qeiA-5kyoA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		3 / 3 PRO A 360
ASN A 118
ARG A 114
 HEM  A 501 (-4.4A)
None
None
 1.09A 2qeuB-5kyoA:
undetectable		 2qeuB-5kyoA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		4 / 4 LEU A  54
PRO A  53
LEU A  71
ARG A  81
 None
 1.39A 3hcoA-5kyoA:
undetectable		 3hcoA-5kyoA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_D_CLMD221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		5 / 12 PHE A 290
LEU A 391
VAL A 401
ALA A 267
HIS A 265
 None
 1.47A 3u9fD-5kyoA:
undetectable
3u9fE-5kyoA:
undetectable		 3u9fD-5kyoA:
18.10
3u9fE-5kyoA:
18.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WRI_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		4 / 5 GLY A 250
THR A 254
ILE A 397
VAL A 398
 HEM  A 501 (-3.8A)
HEM  A 501 (-3.5A)
None
None
 0.41A 3wriA-5kyoA:
52.0		 3wriA-5kyoA:
40.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WRI_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		4 / 5 GLY A 250
THR A 254
ILE A 397
VAL A 398
 HEM  A 501 (-3.8A)
HEM  A 501 (-3.5A)
None
None
 0.42A 3wriB-5kyoA:
52.0		 3wriB-5kyoA:
40.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C9L_A_CAMA1419_0
(CYTOCHROME P450)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		5 / 12 GLY A 250
THR A 254
VAL A 297
ILE A 397
VAL A 398
 HEM  A 501 (-3.8A)
HEM  A 501 (-3.5A)
HEM  A 501 (-4.3A)
None
None
 0.87A 4c9lA-5kyoA:
28.4		 4c9lA-5kyoA:
39.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C9L_A_CAMA1419_0
(CYTOCHROME P450)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		5 / 12 GLY A 251
THR A 254
VAL A 297
ILE A 397
VAL A 398
 HEM  A 501 (-3.3A)
HEM  A 501 (-3.5A)
HEM  A 501 (-4.3A)
None
None
 0.82A 4c9lA-5kyoA:
28.4		 4c9lA-5kyoA:
39.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C9L_B_CAMB1419_0
(CYTOCHROME P450)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		5 / 12 GLY A 251
THR A 254
VAL A 297
ILE A 397
VAL A 398
 HEM  A 501 (-3.3A)
HEM  A 501 (-3.5A)
HEM  A 501 (-4.3A)
None
None
 0.84A 4c9lB-5kyoA:
48.5		 4c9lB-5kyoA:
39.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		5 / 12 GLY A 250
THR A 254
VAL A 297
ILE A 397
VAL A 398
 HEM  A 501 (-3.8A)
HEM  A 501 (-3.5A)
HEM  A 501 (-4.3A)
None
None
 0.90A 4c9oA-5kyoA:
48.6		 4c9oA-5kyoA:
39.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		5 / 12 GLY A 251
THR A 254
VAL A 297
ILE A 397
VAL A 398
 HEM  A 501 (-3.3A)
HEM  A 501 (-3.5A)
HEM  A 501 (-4.3A)
None
None
 0.79A 4c9oA-5kyoA:
48.6		 4c9oA-5kyoA:
39.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		5 / 12 GLY A 250
THR A 254
VAL A 297
ILE A 397
VAL A 398
 HEM  A 501 (-3.8A)
HEM  A 501 (-3.5A)
HEM  A 501 (-4.3A)
None
None
 0.90A 4c9oB-5kyoA:
48.4		 4c9oB-5kyoA:
39.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		5 / 12 GLY A 251
THR A 254
VAL A 297
ILE A 397
VAL A 398
 HEM  A 501 (-3.3A)
HEM  A 501 (-3.5A)
HEM  A 501 (-4.3A)
None
None
 0.81A 4c9oB-5kyoA:
48.4		 4c9oB-5kyoA:
39.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_A_PQNA846_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		5 / 10 PHE A 144
ALA A 137
LEU A 140
GLY A 143
ALA A 183
 None
 1.48A 4fe1A-5kyoA:
undetectable
4fe1J-5kyoA:
undetectable		 4fe1A-5kyoA:
20.16
4fe1J-5kyoA:
5.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JX1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		5 / 10 GLY A 250
THR A 254
VAL A 297
ILE A 397
VAL A 398
 HEM  A 501 (-3.8A)
HEM  A 501 (-3.5A)
HEM  A 501 (-4.3A)
None
None
 0.45A 4jx1B-5kyoA:
52.8		 4jx1B-5kyoA:
40.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JX1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		5 / 10 GLY A 251
THR A 254
VAL A 297
ILE A 397
VAL A 398
 HEM  A 501 (-3.3A)
HEM  A 501 (-3.5A)
HEM  A 501 (-4.3A)
None
None
 0.80A 4jx1B-5kyoA:
52.8		 4jx1B-5kyoA:
40.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		4 / 8 ARG A 341
ASP A 285
LEU A 342
ILE A 276
 None
 1.06A 4k0bA-5kyoA:
undetectable		 4k0bA-5kyoA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		4 / 8 ARG A 341
ASP A 285
LEU A 342
ILE A 276
 None
 0.93A 4l7iA-5kyoA:
undetectable		 4l7iA-5kyoA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		4 / 5 ARG A 374
PRO A 280
ILE A 283
ASP A 284
 None
 1.49A 4z4hA-5kyoA:
undetectable		 4z4hA-5kyoA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_E_ACTE406_0
(PROTON-GATED ION
CHANNEL)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		4 / 5 ILE A 243
ILE A 245
ARG A 203
GLU A 241
 None
 1.13A 4zzcE-5kyoA:
2.1		 4zzcE-5kyoA:
23.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		5 / 9 VAL A 249
GLY A 250
THR A 254
VAL A 297
VAL A 398
 None
HEM  A 501 (-3.8A)
HEM  A 501 (-3.5A)
HEM  A 501 (-4.3A)
None
 0.87A 5cp4A-5kyoA:
50.2		 5cp4A-5kyoA:
40.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		5 / 9 VAL A 249
GLY A 251
THR A 254
VAL A 297
VAL A 398
 None
HEM  A 501 (-3.3A)
HEM  A 501 (-3.5A)
HEM  A 501 (-4.3A)
None
 0.94A 5cp4A-5kyoA:
50.2		 5cp4A-5kyoA:
40.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 5kyo CYP101J2
(Sphingobium
yanoikuyae) 		4 / 8 SER A 264
TYR A 393
GLY A 396
VAL A 296
 None
 1.01A 6giqL-5kyoA:
undetectable
6giqP-5kyoA:
undetectable
6giqT-5kyoA:
undetectable		 6giqL-5kyoA:
23.61
6giqP-5kyoA:
19.34
6giqT-5kyoA:
8.88