SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kza'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LG1_A_SAMA301_0 (PROTEIN-LYSINE METHYLTRANSFERASE METTL21D)	5kza	VIRUS MATRIX PROTEIN (Rous sarcoma virus)	5 / 12	ALA A 11 LEU A 33 LEU A 30 TRP A 74 ALA A 80	None	1.02A	4lg1A-5kzaA: undetectable	4lg1A-5kzaA: 18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LG1_B_SAMB301_0 (PROTEIN-LYSINE METHYLTRANSFERASE METTL21D)	5kza	VIRUS MATRIX PROTEIN (Rous sarcoma virus)	5 / 12	ALA A 11 LEU A 33 LEU A 30 TRP A 74 ALA A 80	None	0.97A	4lg1B-5kzaA: undetectable	4lg1B-5kzaA: 18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LG1_C_SAMC301_0 (PROTEIN-LYSINE METHYLTRANSFERASE METTL21D)	5kza	VIRUS MATRIX PROTEIN (Rous sarcoma virus)	5 / 12	ALA A 11 LEU A 33 LEU A 30 TRP A 74 ALA A 80	None	1.01A	4lg1C-5kzaA: undetectable	4lg1C-5kzaA: 18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4POO_A_SAMA301_0 (PUTATIVE RNA METHYLASE)	5kza	VIRUS MATRIX PROTEIN (Rous sarcoma virus)	5 / 12	GLY A 79 ILE A 8 SER A 9 LEU A 78 THR A 73	None	1.33A	4pooA-5kzaA: undetectable	4pooA-5kzaA: 22.47

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4LG1_A_SAMA301_0","PROTEIN-LYSINE METHYLTRANSFERASE METTL21D","5kza","VIRUS MATRIX PROTEIN","Rous sarcoma virus",5,"ALA A  11;LEU A  33;LEU A  30;TRP A  74;ALA A  80","None","1.02A","4lg1A-5kzaA:undetectable","4lg1A-5kzaA:18.58"],["4LG1_B_SAMB301_0","PROTEIN-LYSINE METHYLTRANSFERASE METTL21D","5kza","VIRUS MATRIX PROTEIN","Rous sarcoma virus",5,"ALA A  11;LEU A  33;LEU A  30;TRP A  74;ALA A  80","None","0.97A","4lg1B-5kzaA:undetectable","4lg1B-5kzaA:18.58"],["4LG1_C_SAMC301_0","PROTEIN-LYSINE METHYLTRANSFERASE METTL21D","5kza","VIRUS MATRIX PROTEIN","Rous sarcoma virus",5,"ALA A  11;LEU A  33;LEU A  30;TRP A  74;ALA A  80","None","1.01A","4lg1C-5kzaA:undetectable","4lg1C-5kzaA:18.58"],["4POO_A_SAMA301_0","PUTATIVE RNA METHYLASE","5kza","VIRUS MATRIX PROTEIN","Rous sarcoma virus",5,"GLY A  79;ILE A   8;SER A   9;LEU A  78;THR A  73","None","1.33A","4pooA-5kzaA:undetectable","4pooA-5kzaA:22.47"]]