SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5l0j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_A_J01A1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 5l0j VINCULIN
(Homo
sapiens) 		5 / 12 MET A 926
ILE A 919
ALA A 957
THR A1037
LEU A 905
 None
 1.25A 2japA-5l0jA:
undetectable		 2japA-5l0jA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_B_J01B1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 5l0j VINCULIN
(Homo
sapiens) 		5 / 12 MET A 926
ILE A 919
ALA A 957
THR A1037
LEU A 905
 None
 1.24A 2japB-5l0jA:
undetectable		 2japB-5l0jA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_C_J01C1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 5l0j VINCULIN
(Homo
sapiens) 		5 / 12 MET A 926
ILE A 919
ALA A 957
THR A1037
LEU A 905
 None
 1.26A 2japC-5l0jA:
undetectable		 2japC-5l0jA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_D_J01D1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 5l0j VINCULIN
(Homo
sapiens) 		5 / 12 MET A 926
ILE A 919
ALA A 957
THR A1037
LEU A 905
 None
 1.26A 2japD-5l0jA:
undetectable		 2japD-5l0jA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5l0j VINCULIN
(Homo
sapiens) 		5 / 12 ILE A 919
ALA A 922
ALA A 923
ALA A 957
VAL A 984
 None
 0.70A 4k6iA-5l0jA:
undetectable		 4k6iA-5l0jA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YVN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 5l0j VINCULIN
(Homo
sapiens) 		4 / 6 GLN A 994
LYS A 996
LEU A 995
LEU A1030
 None
 1.17A 5yvnA-5l0jA:
undetectable		 5yvnA-5l0jA:
20.90