SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5l0q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 5l0q MAB 8C7 HEAVY CHAIN
(Homo
sapiens) 		4 / 8 ALA C  58
VAL C  72
THR C  71
ASP C  55
 None
 1.06A 2kotB-5l0qC:
undetectable		 2kotB-5l0qC:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 5l0q MAB 8C7 HEAVY CHAIN
(Homo
sapiens) 		5 / 12 VAL C 170
VAL C 188
SER C 186
ASN C 203
ASN C 162
 None
 1.43A 3nyaA-5l0qC:
undetectable		 3nyaA-5l0qC:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA602_1
(SERUM ALBUMIN)		 5l0q MAB 8C7 HEAVY CHAIN
(Homo
sapiens) 		5 / 12 LEU C  20
TYR C  94
SER C  16
LEU C  86
SER C  91
 None
None
SO4  C 303 (-4.3A)
None
None
 1.21A 4zbrA-5l0qC:
undetectable		 4zbrA-5l0qC:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_NPSA602_1
(SERUM ALBUMIN)		 5l0q MAB 8C7 HEAVY CHAIN
(Homo
sapiens) 		5 / 12 LEU C  20
TYR C  94
SER C  16
LEU C  86
SER C  91
 None
None
SO4  C 303 (-4.3A)
None
None
 1.20A 5dbyA-5l0qC:
undetectable		 5dbyA-5l0qC:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 5l0q MAB 8C7 HEAVY CHAIN
(Homo
sapiens) 		3 / 3 SER C 210
ALA C 205
VAL C 204
 None
 0.52A 5xiwC-5l0qC:
undetectable		 5xiwC-5l0qC:
17.06