SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5l0v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1433_1
(CHITINASE)		 5l0v PROTEIN
O-GLUCOSYLTRANSFERAS
E 1
(Homo
sapiens) 		4 / 5 TRP A 164
TYR A 161
ASP A 133
PHE A 104
 None
 1.20A 2a3bA-5l0vA:
undetectable		 2a3bA-5l0vA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 5l0v PROTEIN
O-GLUCOSYLTRANSFERAS
E 1
(Homo
sapiens) 		3 / 3 PRO A 135
PHE A 150
ALA A 275
 None
 0.70A 3itaD-5l0vA:
undetectable		 3itaD-5l0vA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O79_B_ASCB303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 5l0v PROTEIN
O-GLUCOSYLTRANSFERAS
E 1
(Homo
sapiens) 		4 / 6 TYR A 372
ARG A  74
ALA A  78
MET A  77
 None
 1.29A 4o79B-5l0vA:
0.2		 4o79B-5l0vA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 5l0v PROTEIN
O-GLUCOSYLTRANSFERAS
E 1
(Homo
sapiens) 		4 / 6 TYR A 372
ARG A  74
ALA A  78
MET A  77
 None
 1.20A 4o7gB-5l0vA:
0.0		 4o7gB-5l0vA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 5l0v PROTEIN
O-GLUCOSYLTRANSFERAS
E 1
(Homo
sapiens) 		3 / 3 PRO A 171
LEU A 181
HIS A 262
 UDP  A1005 ( 4.8A)
UDP  A1005 (-4.8A)
None
 0.71A 4pevA-5l0vA:
3.9		 4pevA-5l0vA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M67_C_ACTC504_0
(ADENOSYLHOMOCYSTEINA
SE)		 5l0v PROTEIN
O-GLUCOSYLTRANSFERAS
E 1
(Homo
sapiens) 		4 / 4 ASP A 219
ILE A 222
ARG A 226
ARG A 213
 None
 1.34A 5m67C-5l0vA:
2.4		 5m67C-5l0vA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_2
(PROTEIN CYP51)		 5l0v PROTEIN
O-GLUCOSYLTRANSFERAS
E 1
(Homo
sapiens) 		4 / 7 VAL A 328
PRO A 220
LEU A 223
LEU A 318
 None
None
MPD  A1006 ( 4.4A)
MPD  A1006 ( 4.6A)
 1.09A 6aycA-5l0vA:
undetectable		 6aycA-5l0vA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_BEZA401_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 5l0v PROTEIN
O-GLUCOSYLTRANSFERAS
E 1
(Homo
sapiens) 		5 / 9 LEU A  43
SER A  42
ILE A 338
VAL A 334
ILE A  39
 NAG  A1001 (-3.5A)
None
None
None
None
 1.20A 6ef6A-5l0vA:
undetectable		 6ef6A-5l0vA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5l0v PROTEIN
O-GLUCOSYLTRANSFERAS
E 1
(Homo
sapiens) 		4 / 5 TYR A 161
VAL A 374
PHE A 114
GLY A 110
 None
 1.31A 6hd4A-5l0vA:
undetectable		 6hd4A-5l0vA:
14.03