SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5l0y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 5l0y SEC72-SSA1
C-TERMINAL PEPTIDE
FUSION PROTEIN
(Saccharomyces
cerevisiae;
Chaetomium
thermophilum) 		5 / 12 GLY A  93
ALA A 132
ASP A  94
ALA A  95
TYR A  99
 None
 1.41A 2avdB-5l0yA:
undetectable		 2avdB-5l0yA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_H_LFXH0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 5l0y SEC72-SSA1
C-TERMINAL PEPTIDE
FUSION PROTEIN
(Chaetomium
thermophilum;
Saccharomyces
cerevisiae) 		4 / 6 SER A 127
ARG A 183
GLY A 184
GLU A 179
 None
 1.00A 3k9fA-5l0yA:
undetectable
3k9fB-5l0yA:
undetectable
3k9fD-5l0yA:
undetectable		 3k9fA-5l0yA:
16.12
3k9fB-5l0yA:
16.12
3k9fD-5l0yA:
20.88