SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5l1b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		8 / 12 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
LYS A 763
 None
 0.67A 1lbcA-5l1bA:
22.5
1lbcC-5l1bA:
22.4		 1lbcA-5l1bA:
34.90
1lbcC-5l1bA:
34.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_B_CYZB329_1
(GLUTAMINE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		8 / 9 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
LYS A 763
 None
 0.76A 1lbcB-5l1bA:
22.2		 1lbcB-5l1bA:
34.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_C_CYZC331_1
(GLUTAMINE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		7 / 12 LYS A 493
PRO A 494
MET A 496
LEU A 751
SER A 754
LEU A 759
LYS A 763
 None
 0.64A 1lbcA-5l1bA:
22.5
1lbcC-5l1bA:
22.4		 1lbcA-5l1bA:
34.90
1lbcC-5l1bA:
34.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_C_CYZC331_1
(GLUTAMINE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		7 / 12 LYS A 493
PRO A 494
MET A 496
SER A 497
SER A 754
LEU A 759
LYS A 763
 None
 0.60A 1lbcA-5l1bA:
22.5
1lbcC-5l1bA:
22.4		 1lbcA-5l1bA:
34.90
1lbcC-5l1bA:
34.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_1
(POL POLYPROTEIN)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 11 LEU A 363
GLY A 239
ALA A 240
ILE A 209
VAL A 242
 None
 0.81A 1t7jA-5l1bA:
undetectable		 1t7jA-5l1bA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 11 ASP A 138
ARG A 141
VAL A 205
TYR A 177
ILE A 168
 None
 1.41A 1tcoC-5l1bA:
undetectable		 1tcoC-5l1bA:
8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		4 / 8 GLY A 733
ILE A 734
ASN A 747
SER A 492
 None
 1.01A 2a8tB-5l1bA:
undetectable		 2a8tB-5l1bA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 11 ASP A 138
ARG A 141
VAL A 205
TYR A 177
ILE A 168
 None
 1.35A 2vn1A-5l1bA:
undetectable		 2vn1A-5l1bA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 10 ILE A  14
GLY A  16
ILE A  97
MET A 292
MET A  33
 None
 1.44A 3adsA-5l1bA:
undetectable		 3adsA-5l1bA:
15.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_A_CYZA265_1
(GLUTAMATE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		7 / 11 LYS A 493
PRO A 494
MET A 496
LEU A 751
SER A 754
LEU A 759
LYS A 763
 None
 0.59A 3h6tA-5l1bA:
22.5
3h6tC-5l1bA:
22.4		 3h6tA-5l1bA:
34.90
3h6tC-5l1bA:
34.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_A_CYZA265_1
(GLUTAMATE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		6 / 11 PRO A 494
MET A 496
SER A 497
SER A 754
LEU A 759
LYS A 763
 None
 0.54A 3h6tA-5l1bA:
22.5
3h6tC-5l1bA:
22.4		 3h6tA-5l1bA:
34.90
3h6tC-5l1bA:
34.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_B_CYZB265_1
(GLUTAMATE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		6 / 9 LYS A 493
PRO A 494
MET A 496
LEU A 751
SER A 754
LEU A 759
 None
 0.48A 3h6tB-5l1bA:
22.2		 3h6tB-5l1bA:
34.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_B_CYZB265_1
(GLUTAMATE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		7 / 9 LYS A 493
PRO A 494
MET A 496
SER A 497
SER A 754
LEU A 759
LYS A 763
 None
 0.63A 3h6tB-5l1bA:
22.2		 3h6tB-5l1bA:
34.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_C_CYZC265_1
(GLUTAMATE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		7 / 11 LYS A 493
PRO A 494
MET A 496
LEU A 751
SER A 754
LEU A 759
LYS A 763
 None
 0.56A 3h6tA-5l1bA:
22.5
3h6tC-5l1bA:
22.4		 3h6tA-5l1bA:
34.90
3h6tC-5l1bA:
34.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_C_CYZC265_1
(GLUTAMATE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		7 / 11 LYS A 493
PRO A 494
MET A 496
SER A 497
SER A 754
LEU A 759
LYS A 763
 None
 0.63A 3h6tA-5l1bA:
22.5
3h6tC-5l1bA:
22.4		 3h6tA-5l1bA:
34.90
3h6tC-5l1bA:
34.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 10 ASP A 138
ARG A 141
VAL A 205
TYR A 177
ILE A 168
 None
 1.42A 3ihzA-5l1bA:
undetectable		 3ihzA-5l1bA:
10.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		4 / 5 LYS A 493
PRO A 494
LEU A 751
SER A 754
 None
 0.54A 3ijxH-5l1bA:
22.1		 3ijxH-5l1bA:
70.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 10 ILE A 481
PRO A 494
SER A 497
LYS A 730
GLY A 731
 None
 0.62A 3ik6B-5l1bA:
22.4
3ik6E-5l1bA:
22.6		 3ik6B-5l1bA:
70.44
3ik6E-5l1bA:
70.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_B_TRUB800_1
(GLUTAMATE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		8 / 12 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
LYS A 763
 None
 0.56A 3iltB-5l1bA:
19.5
3iltE-5l1bA:
19.1		 3iltB-5l1bA:
70.44
3iltE-5l1bA:
70.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_E_TRUE800_1
(GLUTAMATE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		8 / 10 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
LYS A 763
 None
 0.59A 3iltB-5l1bA:
19.5
3iltE-5l1bA:
19.1		 3iltB-5l1bA:
70.44
3iltE-5l1bA:
70.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		4 / 5 LYS A 493
PRO A 494
LEU A 751
SER A 754
 None
 0.44A 3iluH-5l1bA:
22.3		 3iluH-5l1bA:
70.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_B_PZIB800_0
(GLUTAMATE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		7 / 10 TYR A 424
PRO A 494
MET A 496
SER A 497
SER A 754
LEU A 759
ASP A 760
 None
 0.50A 3lsfB-5l1bA:
22.4
3lsfE-5l1bA:
22.3		 3lsfB-5l1bA:
70.44
3lsfE-5l1bA:
70.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_E_PZIE800_0
(GLUTAMATE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		7 / 10 PRO A 494
MET A 496
SER A 497
SER A 754
LEU A 759
ASP A 760
LYS A 763
 None
 0.54A 3lsfB-5l1bA:
22.4
3lsfE-5l1bA:
22.3		 3lsfB-5l1bA:
70.44
3lsfE-5l1bA:
70.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		8 / 8 TYR A 424
PRO A 494
MET A 496
SER A 497
SER A 754
LEU A 759
ASP A 760
LYS A 763
 None
 0.56A 3lsfH-5l1bA:
22.1		 3lsfH-5l1bA:
70.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 7 TYR A 424
MET A 496
LEU A 759
ASP A 760
LYS A 763
 None
 0.67A 3lslA-5l1bA:
22.2
3lslD-5l1bA:
22.4		 3lslA-5l1bA:
70.17
3lslD-5l1bA:
70.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 7 TYR A 424
MET A 496
LEU A 759
ASP A 760
LYS A 763
 None
 0.64A 3lslA-5l1bA:
22.2
3lslD-5l1bA:
22.4		 3lslA-5l1bA:
70.17
3lslD-5l1bA:
70.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 6 TYR A 424
MET A 496
LEU A 759
ASP A 760
LYS A 763
 None
 0.63A 3lslG-5l1bA:
22.2		 3lslG-5l1bA:
70.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_SALB900_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		4 / 5 VAL A 255
TYR A 250
ILE A 278
ALA A 283
 None
 0.96A 3n8yB-5l1bA:
undetectable		 3n8yB-5l1bA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 11 ASP A 138
ARG A 141
VAL A 205
TYR A 177
ILE A 168
 None
 1.40A 3o5rA-5l1bA:
undetectable		 3o5rA-5l1bA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		3 / 3 ILE A 712
VAL A 690
ARG A 694
 None
 0.76A 3p73A-5l1bA:
undetectable		 3p73A-5l1bA:
15.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_A_CYZA266_1
(GLUTAMATE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		9 / 9 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
ASP A 760
LYS A 763
 None
 0.60A 3tkdA-5l1bA:
22.3		 3tkdA-5l1bA:
34.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		4 / 5 ILE A 481
PRO A 494
LYS A 730
GLY A 731
 None
 0.53A 3tkdB-5l1bA:
21.7		 3tkdB-5l1bA:
34.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		4 / 5 ILE A 481
PRO A 494
LYS A 730
GLY A 731
 None
 0.53A 3tkdA-5l1bA:
22.3		 3tkdA-5l1bA:
34.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_B_CYZB267_2
(GLUTAMATE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		8 / 9 LYS A 493
PRO A 494
MET A 496
LEU A 751
SER A 754
LEU A 759
ASP A 760
LYS A 763
 None
 0.48A 3tkdB-5l1bA:
21.7		 3tkdB-5l1bA:
34.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_B_CYZB267_2
(GLUTAMATE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		8 / 9 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
ASP A 760
LYS A 763
 None
 0.62A 3tkdB-5l1bA:
21.7		 3tkdB-5l1bA:
34.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_1
(POL POLYPROTEIN)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 9 LEU A 363
GLY A 239
ALA A 240
ILE A 209
VAL A 242
 None
 0.81A 3u7sA-5l1bA:
undetectable		 3u7sA-5l1bA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 10 ASP A 138
ARG A 141
VAL A 205
TYR A 177
ILE A 168
 None
 1.47A 3uf8A-5l1bA:
undetectable		 3uf8A-5l1bA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 11 ASP A 138
ARG A 141
VAL A 205
TYR A 177
ILE A 168
 None
 1.43A 3vawA-5l1bA:
undetectable		 3vawA-5l1bA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4APJ_A_ACTA1635_0
(ANGIOTENSIN-CONVERTI
NG ENZYME
BRADYKININ-POTENTIAT
ING PEPTIDE B)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		4 / 6 HIS A  93
GLU A 330
SER A  95
PRO A 108
 None
 1.33A 4apjA-5l1bA:
2.8
4apjP-5l1bA:
undetectable		 4apjA-5l1bA:
21.31
4apjP-5l1bA:
2.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 10 ASP A 138
ARG A 141
VAL A 205
TYR A 177
ILE A 168
 None
 1.38A 4dz3A-5l1bA:
undetectable		 4dz3A-5l1bA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 10 ASP A 138
ARG A 141
VAL A 205
TYR A 177
ILE A 168
 None
 1.44A 4dz3B-5l1bA:
undetectable		 4dz3B-5l1bA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		4 / 7 VAL A 291
MET A 292
ALA A 295
PHE A 296
 None
 0.91A 4lb2A-5l1bA:
undetectable		 4lb2A-5l1bA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 12 VAL A 396
ALA A 472
GLY A 239
GLY A 470
THR A 394
 None
 1.13A 4mm8A-5l1bA:
undetectable		 4mm8A-5l1bA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		4 / 5 ILE A 358
HIS A 219
TYR A 135
VAL A 149
 None
 1.05A 4s0vA-5l1bA:
4.0		 4s0vA-5l1bA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1008_1
(SERUM ALBUMIN)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 9 ALA A 583
PHE A 584
VAL A 538
SER A 576
LEU A 577
 None
 1.00A 4z69A-5l1bA:
4.2		 4z69A-5l1bA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_C7HA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		4 / 5 GLY A 212
TYR A 220
TYR A 218
GLY A 217
 None
 1.05A 5ayfA-5l1bA:
undetectable		 5ayfA-5l1bA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		4 / 5 THR A 275
ALA A 276
THR A 277
TYR A 250
 None
 1.28A 5ecmA-5l1bA:
undetectable		 5ecmA-5l1bA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 11 ASP A 138
ARG A 141
VAL A 205
TYR A 177
ILE A 168
 None
 1.39A 5hwcA-5l1bA:
undetectable		 5hwcA-5l1bA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		4 / 6 GLY A 230
ASP A 138
ILE A 193
TYR A 280
 None
 1.10A 5iwuA-5l1bA:
undetectable		 5iwuA-5l1bA:
16.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		4 / 7 ASP A 519
TYR A 616
SER A 788
ASN A 791
 None
 0.87A 5l1fC-5l1bA:
46.0		 5l1fC-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		4 / 7 SER A 516
ASP A 519
TYR A 616
ASN A 791
 None
 1.00A 5l1fC-5l1bA:
46.0		 5l1fC-5l1bA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		4 / 7 LEU A 639
THR A 655
TRP A 671
MET A 674
 None
 1.36A 5ljcA-5l1bA:
0.0		 5ljcA-5l1bA:
11.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DLZ_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 10 MET A 496
SER A 497
LEU A 751
ASP A 760
LYS A 763
 None
 1.00A 6dlzA-5l1bA:
40.4
6dlzD-5l1bA:
40.2		 6dlzA-5l1bA:
100.00
6dlzD-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DLZ_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 10 MET A 496
LEU A 751
LEU A 759
ASP A 760
LYS A 763
 None
 0.80A 6dlzB-5l1bA:
40.2
6dlzC-5l1bA:
40.4		 6dlzB-5l1bA:
100.00
6dlzC-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DLZ_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 10 MET A 496
LEU A 751
SER A 754
LEU A 759
LYS A 763
 None
 0.96A 6dlzB-5l1bA:
40.2
6dlzC-5l1bA:
40.4		 6dlzB-5l1bA:
100.00
6dlzC-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DLZ_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 10 MET A 496
SER A 497
LEU A 751
LEU A 759
LYS A 763
 None
 0.80A 6dlzB-5l1bA:
40.2
6dlzC-5l1bA:
40.4		 6dlzB-5l1bA:
100.00
6dlzC-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DLZ_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 10 MET A 496
SER A 497
LEU A 751
ASP A 760
LYS A 763
 None
 1.00A 6dlzB-5l1bA:
40.2
6dlzC-5l1bA:
40.4		 6dlzB-5l1bA:
100.00
6dlzC-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DLZ_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 11 MET A 496
LEU A 751
LEU A 759
ASP A 760
LYS A 763
 None
 0.80A 6dlzA-5l1bA:
40.4
6dlzD-5l1bA:
40.2		 6dlzA-5l1bA:
100.00
6dlzD-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DLZ_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 11 MET A 496
LEU A 751
SER A 754
LEU A 759
LYS A 763
 None
 0.97A 6dlzA-5l1bA:
40.4
6dlzD-5l1bA:
40.2		 6dlzA-5l1bA:
100.00
6dlzD-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DLZ_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 11 MET A 496
SER A 497
LEU A 751
LEU A 759
LYS A 763
 None
 0.80A 6dlzA-5l1bA:
40.4
6dlzD-5l1bA:
40.2		 6dlzA-5l1bA:
100.00
6dlzD-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM0_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 9 MET A 496
SER A 497
LEU A 751
ASP A 760
LYS A 763
 None
 0.98A 6dm0A-5l1bA:
42.9
6dm0D-5l1bA:
40.1		 6dm0A-5l1bA:
100.00
6dm0D-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 10 MET A 496
LEU A 751
LEU A 759
ASP A 760
LYS A 763
 None
 0.80A 6dm0B-5l1bA:
40.1
6dm0C-5l1bA:
42.9		 6dm0B-5l1bA:
100.00
6dm0C-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 10 MET A 496
SER A 497
LEU A 751
LEU A 759
LYS A 763
 None
 0.77A 6dm0B-5l1bA:
40.1
6dm0C-5l1bA:
42.9		 6dm0B-5l1bA:
100.00
6dm0C-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM0_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 9 MET A 496
SER A 497
LEU A 751
ASP A 760
LYS A 763
 None
 0.98A 6dm0B-5l1bA:
40.1
6dm0C-5l1bA:
42.9		 6dm0B-5l1bA:
100.00
6dm0C-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM0_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 9 MET A 496
LEU A 751
LEU A 759
ASP A 760
LYS A 763
 None
 0.80A 6dm0A-5l1bA:
42.9
6dm0D-5l1bA:
40.1		 6dm0A-5l1bA:
100.00
6dm0D-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM0_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 9 MET A 496
SER A 497
LEU A 751
LEU A 759
LYS A 763
 None
 0.78A 6dm0A-5l1bA:
42.9
6dm0D-5l1bA:
40.1		 6dm0A-5l1bA:
100.00
6dm0D-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM1_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 10 MET A 496
SER A 497
LEU A 751
ASP A 760
LYS A 763
 None
 0.99A 6dm1A-5l1bA:
40.4
6dm1D-5l1bA:
40.1		 6dm1A-5l1bA:
100.00
6dm1D-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 10 MET A 496
LEU A 751
LEU A 759
ASP A 760
LYS A 763
 None
 0.80A 6dm1B-5l1bA:
40.1
6dm1C-5l1bA:
40.4		 6dm1B-5l1bA:
100.00
6dm1C-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 10 MET A 496
LEU A 751
SER A 754
LEU A 759
LYS A 763
 None
 0.96A 6dm1B-5l1bA:
40.1
6dm1C-5l1bA:
40.4		 6dm1B-5l1bA:
100.00
6dm1C-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 10 MET A 496
SER A 497
LEU A 751
LEU A 759
LYS A 763
 None
 0.81A 6dm1B-5l1bA:
40.1
6dm1C-5l1bA:
40.4		 6dm1B-5l1bA:
100.00
6dm1C-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM1_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 10 MET A 496
SER A 497
LEU A 751
ASP A 760
LYS A 763
 None
 0.99A 6dm1B-5l1bA:
40.1
6dm1C-5l1bA:
40.4		 6dm1B-5l1bA:
100.00
6dm1C-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM1_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 11 MET A 496
LEU A 751
LEU A 759
ASP A 760
LYS A 763
 None
 0.79A 6dm1A-5l1bA:
40.4
6dm1D-5l1bA:
40.1		 6dm1A-5l1bA:
100.00
6dm1D-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM1_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 11 MET A 496
LEU A 751
SER A 754
LEU A 759
LYS A 763
 None
 0.96A 6dm1A-5l1bA:
40.4
6dm1D-5l1bA:
40.1		 6dm1A-5l1bA:
100.00
6dm1D-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM1_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 11 MET A 496
SER A 497
LEU A 751
LEU A 759
LYS A 763
 None
 0.80A 6dm1A-5l1bA:
40.4
6dm1D-5l1bA:
40.1		 6dm1A-5l1bA:
100.00
6dm1D-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM2_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 9 MET A 496
SER A 497
LEU A 751
ASP A 760
LYS A 763
 None
 0.95A 6dm2A-5l1bA:
41.9
6dm2D-5l1bA:
40.1		 6dm2A-5l1bA:
100.00
6dm2D-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM2_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 10 MET A 496
LEU A 751
LEU A 759
ASP A 760
LYS A 763
 None
 0.83A 6dm2B-5l1bA:
40.2
6dm2C-5l1bA:
41.9		 6dm2B-5l1bA:
100.00
6dm2C-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM2_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 10 MET A 496
LEU A 751
SER A 754
LEU A 759
LYS A 763
 None
 0.96A 6dm2B-5l1bA:
40.2
6dm2C-5l1bA:
41.9		 6dm2B-5l1bA:
100.00
6dm2C-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM2_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 9 MET A 496
SER A 497
LEU A 751
ASP A 760
LYS A 763
 None
 0.95A 6dm2B-5l1bA:
40.2
6dm2C-5l1bA:
41.9		 6dm2B-5l1bA:
100.00
6dm2C-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM2_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 10 MET A 496
LEU A 751
LEU A 759
ASP A 760
LYS A 763
 None
 0.84A 6dm2A-5l1bA:
41.9
6dm2D-5l1bA:
40.1		 6dm2A-5l1bA:
100.00
6dm2D-5l1bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM2_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 10 MET A 496
LEU A 751
SER A 754
LEU A 759
LYS A 763
 None
 0.97A 6dm2A-5l1bA:
41.9
6dm2D-5l1bA:
40.1		 6dm2A-5l1bA:
100.00
6dm2D-5l1bA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 5l1b GLUTAMATE RECEPTOR
2,GLUTAMATE RECEPTOR
2
(Rattus
norvegicus) 		5 / 10 ASP A 138
ARG A 141
VAL A 205
TYR A 177
ILE A 168
 None
 1.45A 6mkeD-5l1bA:
undetectable		 6mkeD-5l1bA:
6.92