SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5l20'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_C_PPFC413_1
(PHOSPHONOACETATE
HYDROLASE)		 5l20 CLOSTRIPAIN-RELATED
PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 8 THR B 392
ASP B 373
HIS B 393
ILE B 291
 None
 0.99A 1ei6C-5l20B:
undetectable		 1ei6C-5l20B:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_B_NIOB219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5l20 CLOSTRIPAIN-RELATED
PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 6 PHE B 259
GLY B 271
SER B 230
THR B 229
 None
 1.08A 1icuA-5l20B:
undetectable
1icuB-5l20B:
undetectable		 1icuA-5l20B:
21.12
1icuB-5l20B:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_D_NIOD223_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5l20 CLOSTRIPAIN-RELATED
PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 5 PHE B 259
GLY B 271
SER B 230
THR B 229
 None
 1.16A 1icuC-5l20B:
undetectable
1icuD-5l20B:
undetectable		 1icuC-5l20B:
21.12
1icuD-5l20B:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_B_NIOB702_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5l20 CLOSTRIPAIN-RELATED
PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 5 PHE B 259
GLY B 271
SER B 230
THR B 229
 None
 1.08A 1icvA-5l20B:
undetectable
1icvB-5l20B:
undetectable		 1icvA-5l20B:
21.12
1icvB-5l20B:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5l20 CLOSTRIPAIN-RELATED
PROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 9 MET B 209
PHE B 204
SER B 211
ALA B 217
LEU B 218
 None
 1.41A 1jb0A-5l20B:
undetectable		 1jb0A-5l20B:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5l20 CLOSTRIPAIN-RELATED
PROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 11 MET B 209
PHE B 204
SER B 211
ALA B 217
LEU B 218
 None
 1.36A 1jb0B-5l20B:
undetectable		 1jb0B-5l20B:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 5l20 CLOSTRIPAIN-RELATED
PROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 12 PHE A  79
LEU A 122
MET A 136
ILE A 138
LEU B 188
 None
 1.24A 1lhuA-5l20A:
undetectable		 1lhuA-5l20A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 5l20 CLOSTRIPAIN-RELATED
PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 6 ALA B 380
LEU B 379
ILE A 146
SER B 372
 None
 1.08A 1sbrA-5l20B:
undetectable
1sbrB-5l20B:
undetectable		 1sbrA-5l20B:
24.78
1sbrB-5l20B:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH8_A_VIBA1_1
(MAJOR PRION PROTEIN)		 5l20 CLOSTRIPAIN-RELATED
PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 6 HIS A 141
ASP B 205
ASP B 206
TYR B 208
 None
 1.45A 2lh8A-5l20A:
undetectable		 2lh8A-5l20A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_ACTA148_0
(UPF0066 PROTEIN
AF_0241)		 5l20 CLOSTRIPAIN-RELATED
PROTEIN
(Bacteroides
thetaiotaomicron) 		3 / 3 VAL A  66
GLU A  63
GLU A  67
 None
 0.70A 2nv4A-5l20A:
undetectable		 2nv4A-5l20A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5l20 CLOSTRIPAIN-RELATED
PROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 9 MET B 209
PHE B 204
SER B 211
ALA B 217
LEU B 218
 None
 1.34A 2wsfB-5l20B:
undetectable		 2wsfB-5l20B:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_C_VIAC901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 5l20 CLOSTRIPAIN-RELATED
PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 7 TYR A  44
MET B 209
LEU B 218
VAL A 148
 None
 0.96A 3jwqC-5l20A:
undetectable		 3jwqC-5l20A:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_A_PQNA847_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5l20 CLOSTRIPAIN-RELATED
PROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 9 MET B 209
PHE B 204
SER B 211
ALA B 217
LEU B 218
 None
 1.41A 3pcqA-5l20B:
undetectable		 3pcqA-5l20B:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5l20 CLOSTRIPAIN-RELATED
PROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 11 MET B 209
PHE B 204
SER B 211
ALA B 217
LEU B 218
 None
 1.35A 3pcqB-5l20B:
undetectable		 3pcqB-5l20B:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 5l20 CLOSTRIPAIN-RELATED
PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 8 GLY B 243
LEU B 246
ILE B 247
ILE A  76
 None
 0.57A 4em2A-5l20B:
undetectable		 4em2A-5l20B:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y28_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5l20 CLOSTRIPAIN-RELATED
PROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 9 MET B 209
PHE B 204
SER B 211
ALA B 217
LEU B 218
 None
 1.39A 4y28A-5l20B:
undetectable
4y28J-5l20B:
undetectable		 4y28A-5l20B:
16.87
4y28J-5l20B:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_A_GBMA801_1
(PROLINE--TRNA LIGASE)		 5l20 CLOSTRIPAIN-RELATED
PROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 12 TYR B 239
LEU B 246
ILE B 226
GLY B 227
ILE B 273
 None
 0.84A 5ifuA-5l20B:
undetectable		 5ifuA-5l20B:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5l20 CLOSTRIPAIN-RELATED
PROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 9 MET B 209
PHE B 204
SER B 211
ALA B 217
LEU B 218
 None
 1.37A 5l8rA-5l20B:
undetectable		 5l8rA-5l20B:
15.56