SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5l26'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_A_EAAA224_1
(GLUTATHIONE
TRANSFERASE)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		5 / 12 ARG A  53
GLY A  52
LEU A  45
LEU A  42
ALA A  59
 None
None
None
6ZL  A 502 (-4.4A)
6ZL  A 504 ( 4.1A)
 1.17A 1gseA-5l26A:
undetectable		 1gseA-5l26A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		5 / 12 GLY A 401
VAL A 399
ALA A 209
SER A 183
LEU A 132
 None
None
None
NA  A 506 (-2.4A)
None
 1.29A 1kiaD-5l26A:
undetectable		 1kiaD-5l26A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		4 / 8 GLY A 130
MET A 135
ILE A 128
VAL A 127
 None
None
6ZL  A 502 ( 4.7A)
6ZL  A 502 (-4.4A)
 0.98A 1rxcI-5l26A:
undetectable		 1rxcI-5l26A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		5 / 10 PHE A 174
ALA A 400
LEU A 403
LEU A 220
LEU A 375
 None
 1.11A 2bxqA-5l26A:
undetectable		 2bxqA-5l26A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_C_ACTC36_0
(GCN4 LEUCINE ZIPPER)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		5 / 10 SER A 404
ALA A 182
ASN A 405
ALA A 367
SER A 178
 None
 1.25A 2r2vC-5l26A:
undetectable
2r2vF-5l26A:
undetectable
2r2vG-5l26A:
undetectable		 2r2vC-5l26A:
11.45
2r2vF-5l26A:
11.45
2r2vG-5l26A:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_C_X2NC1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		5 / 12 PHE A  36
PHE A 216
VAL A  40
ALA A  17
ALA A  15
 None
 1.24A 2x2nC-5l26A:
undetectable		 2x2nC-5l26A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		5 / 12 ALA A 367
ALA A 205
GLY A 186
THR A 155
VAL A 374
 None
None
6ZL  A 501 ( 4.4A)
URI  A 505 ( 4.5A)
URI  A 505 (-4.6A)
 1.05A 3c6gA-5l26A:
undetectable		 3c6gA-5l26A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_B_VD3B700_1
(CYTOCHROME P450 2R1)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		5 / 12 ALA A 367
ALA A 205
GLY A 186
THR A 155
VAL A 374
 None
None
6ZL  A 501 ( 4.4A)
URI  A 505 ( 4.5A)
URI  A 505 (-4.6A)
 1.09A 3c6gB-5l26A:
undetectable		 3c6gB-5l26A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		6 / 12 GLY A 180
GLY A 179
ALA A 209
PRO A 158
ALA A 157
ALA A 367
 NA  A 506 ( 4.9A)
None
None
None
None
None
 1.42A 3jb2A-5l26A:
undetectable		 3jb2A-5l26A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		4 / 6 GLY A 130
MET A 135
ILE A 128
VAL A 127
 None
None
6ZL  A 502 ( 4.7A)
6ZL  A 502 (-4.4A)
 1.03A 3kvvA-5l26A:
undetectable		 3kvvA-5l26A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		4 / 6 GLY A 130
MET A 135
ILE A 128
VAL A 127
 None
None
6ZL  A 502 ( 4.7A)
6ZL  A 502 (-4.4A)
 1.00A 3kvvC-5l26A:
undetectable		 3kvvC-5l26A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		4 / 6 GLY A 130
MET A 135
ILE A 128
VAL A 127
 None
None
6ZL  A 502 ( 4.7A)
6ZL  A 502 (-4.4A)
 1.01A 3kvvE-5l26A:
undetectable		 3kvvE-5l26A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		4 / 6 GLY A 130
MET A 135
ILE A 128
VAL A 127
 None
None
6ZL  A 502 ( 4.7A)
6ZL  A 502 (-4.4A)
 0.99A 3kvvF-5l26A:
undetectable		 3kvvF-5l26A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		4 / 6 GLY A 179
GLY A 180
SER A 145
LEU A 379
 None
NA  A 506 ( 4.9A)
None
None
 0.78A 3o9mB-5l26A:
undetectable		 3o9mB-5l26A:
22.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		9 / 12 GLY A 153
GLN A 154
ALA A 185
TYR A 192
ASN A 331
GLU A 332
PHE A 366
ASN A 368
SER A 371
 NA  A 506 (-3.8A)
URI  A 505 (-3.9A)
URI  A 505 ( 3.7A)
None
URI  A 505 ( 4.7A)
URI  A 505 (-3.2A)
URI  A 505 (-3.8A)
URI  A 505 (-3.2A)
URI  A 505 (-2.4A)
 0.41A 4pb1A-5l26A:
63.9		 4pb1A-5l26A:
67.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		6 / 12 GLY A 153
GLU A 156
ALA A 185
TYR A 192
GLU A 332
PHE A 366
 NA  A 506 (-3.8A)
None
URI  A 505 ( 3.7A)
None
URI  A 505 (-3.2A)
URI  A 505 (-3.8A)
 0.83A 4pb1A-5l26A:
63.9		 4pb1A-5l26A:
67.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		5 / 12 GLY A 153
ALA A 185
VAL A 188
TYR A 192
ASN A 405
 NA  A 506 (-3.8A)
URI  A 505 ( 3.7A)
None
None
None
 1.13A 4pd5A-5l26A:
64.0		 4pd5A-5l26A:
67.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		10 / 12 GLY A 153
GLN A 154
ALA A 185
VAL A 188
TYR A 192
ASN A 331
GLU A 332
PHE A 366
ASN A 368
SER A 371
 NA  A 506 (-3.8A)
URI  A 505 (-3.9A)
URI  A 505 ( 3.7A)
None
None
URI  A 505 ( 4.7A)
URI  A 505 (-3.2A)
URI  A 505 (-3.8A)
URI  A 505 (-3.2A)
URI  A 505 (-2.4A)
 0.42A 4pd5A-5l26A:
64.0		 4pd5A-5l26A:
67.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		5 / 12 GLY A 153
ALA A 185
VAL A 188
TYR A 192
ASN A 405
 NA  A 506 (-3.8A)
URI  A 505 ( 3.7A)
None
None
None
 1.14A 4pd9A-5l26A:
63.9		 4pd9A-5l26A:
67.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		9 / 12 GLY A 153
GLN A 154
ALA A 185
VAL A 188
TYR A 192
GLU A 332
PHE A 366
ASN A 368
SER A 371
 NA  A 506 (-3.8A)
URI  A 505 (-3.9A)
URI  A 505 ( 3.7A)
None
None
URI  A 505 (-3.2A)
URI  A 505 (-3.8A)
URI  A 505 (-3.2A)
URI  A 505 (-2.4A)
 0.38A 4pd9A-5l26A:
63.9		 4pd9A-5l26A:
67.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		7 / 12 GLY A 153
GLU A 156
ALA A 185
VAL A 188
TYR A 192
GLU A 332
PHE A 366
 NA  A 506 (-3.8A)
None
URI  A 505 ( 3.7A)
None
None
URI  A 505 (-3.2A)
URI  A 505 (-3.8A)
 0.78A 4pd9A-5l26A:
63.9		 4pd9A-5l26A:
67.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		5 / 12 ILE A 125
THR A  62
LEU A 124
LEU A 111
LEU A 115
 None
6ZL  A 504 (-3.8A)
None
None
None
 1.26A 4qynB-5l26A:
undetectable		 4qynB-5l26A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_B_15UB301_1
(THROMBIN HEAVY CHAIN)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		5 / 12 LEU A 406
LEU A 220
ALA A 217
GLY A 401
GLY A 213
 None
 0.99A 4rn6B-5l26A:
undetectable		 4rn6B-5l26A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		4 / 4 TYR A 342
GLY A 321
SER A 322
LEU A 323
 None
 1.27A 5bphC-5l26A:
undetectable		 5bphC-5l26A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		4 / 6 TYR A 342
GLY A 321
SER A 322
LEU A 323
 None
 1.28A 5bphD-5l26A:
undetectable		 5bphD-5l26A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		5 / 12 GLY A 212
LEU A 403
LEU A 132
GLY A  34
ILE A  38
 None
 1.01A 5d4uC-5l26A:
undetectable		 5d4uC-5l26A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		5 / 12 GLY A 212
LEU A 403
LEU A 132
GLY A  34
ILE A  38
 None
 0.99A 5d4uD-5l26A:
undetectable		 5d4uD-5l26A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		3 / 3 SER A 187
SER A 109
PHE A 366
 URI  A 505 ( 4.3A)
None
URI  A 505 (-3.8A)
 0.88A 5mugA-5l26A:
undetectable		 5mugA-5l26A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_F_CCSF14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		4 / 6 PHE A 303
LEU A 323
SER A 304
GLY A 318
 None
 0.91A 5o4yF-5l26A:
undetectable		 5o4yF-5l26A:
3.02