SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5l2d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 5l2d SURFACE-ASSOCIATED
PROTEIN CSHA
(Streptococcus
gordonii) 		4 / 8 ASP A  14
GLY A  88
PHE A   4
ASP A   6
 None
 0.99A 2aouA-5l2dA:
undetectable		 2aouA-5l2dA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P)		 5l2d SURFACE-ASSOCIATED
PROTEIN CSHA
(Streptococcus
gordonii) 		4 / 8 VAL A 180
ILE A 154
VAL A 224
GLY A 218
 None
 0.68A 3hjoB-5l2dA:
undetectable		 3hjoB-5l2dA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 5l2d SURFACE-ASSOCIATED
PROTEIN CSHA
(Streptococcus
gordonii) 		4 / 6 PHE A  19
PHE A   4
THR A  23
VAL A  39
 None
 1.18A 3lb3B-5l2dA:
undetectable		 3lb3B-5l2dA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_SAMA502_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 5l2d SURFACE-ASSOCIATED
PROTEIN CSHA
(Streptococcus
gordonii) 		5 / 12 ILE A 154
GLY A 226
PRO A 213
VAL A 224
ILE A  50
 None
 1.13A 4rvdA-5l2dA:
undetectable		 4rvdA-5l2dA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 5l2d SURFACE-ASSOCIATED
PROTEIN CSHA
(Streptococcus
gordonii) 		5 / 12 ILE A 154
GLY A 226
PRO A 213
VAL A 224
ILE A  50
 None
 1.12A 4rvgA-5l2dA:
undetectable		 4rvgA-5l2dA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)		 5l2d SURFACE-ASSOCIATED
PROTEIN CSHA
(Streptococcus
gordonii) 		4 / 8 ILE A 154
PRO A 227
MET A 181
ILE A 199
 None
 0.97A 5ieoA-5l2dA:
undetectable		 5ieoA-5l2dA:
19.40