SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5l2p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 8 GLY A  84
SER A 156
PHE A 203
HIS A 281
 None
 0.71A 1ax9A-5l2pA:
17.1		 1ax9A-5l2pA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 6 PHE A 185
HIS A 281
ALA A  85
GLY A 213
 None
 1.02A 1c8lA-5l2pA:
undetectable		 1c8lA-5l2pA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 7 ALA A 243
SER A 273
THR A 271
VAL A 269
 None
 0.86A 1dvxB-5l2pA:
undetectable		 1dvxB-5l2pA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  83
GLY A  84
SER A 156
PHE A 203
HIS A 281
 None
 0.58A 1dx6A-5l2pA:
17.5		 1dx6A-5l2pA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 12 PHE A  81
ARG A  72
VAL A 112
ALA A 132
ILE A  66
 None
 1.03A 1epbB-5l2pA:
1.3		 1epbB-5l2pA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 6 PHE A 185
HIS A 281
ALA A  85
GLY A 213
 None
 1.00A 1gfzA-5l2pA:
5.2		 1gfzA-5l2pA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 6 PHE A 185
HIS A 281
ALA A  85
GLY A 213
 None
 0.97A 1l5qA-5l2pA:
undetectable		 1l5qA-5l2pA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 6 PHE A 185
HIS A 281
ALA A  85
GLY A 213
 None
 1.03A 1l5qB-5l2pA:
2.8		 1l5qB-5l2pA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 6 PHE A 185
HIS A 281
ALA A  85
GLY A 213
 None
 1.02A 1l7xA-5l2pA:
2.9		 1l7xA-5l2pA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 6 PHE A 185
HIS A 281
ALA A  85
GLY A 213
 None
 1.02A 1l7xB-5l2pA:
undetectable		 1l7xB-5l2pA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  83
GLY A  84
SER A 156
PHE A 203
HIS A 281
 None
 0.48A 1w6rA-5l2pA:
17.7		 1w6rA-5l2pA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 6 GLY A  83
SER A 156
LEU A  88
HIS A 281
 None
 0.89A 1yajF-5l2pA:
17.6		 1yajF-5l2pA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 6 LEU A  38
GLY A  84
SER A 156
HIS A 281
 None
 0.90A 1yajF-5l2pA:
17.6		 1yajF-5l2pA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 12 HIS A  82
LEU A  38
LEU A 204
LEU A 116
TYR A 114
 None
 1.37A 1zgyA-5l2pA:
undetectable		 1zgyA-5l2pA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 9 GLY A  83
GLY A  84
SER A 156
ALA A 157
HIS A 281
 None
 0.90A 2aceA-5l2pA:
4.8		 2aceA-5l2pA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2002_1
(SERUM ALBUMIN)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 10 ALA A  85
ALA A 157
LEU A 161
ALA A 125
LEU A  88
 None
 0.80A 2bxeA-5l2pA:
undetectable		 2bxeA-5l2pA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2002_1
(SERUM ALBUMIN)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 10 ALA A  85
ALA A 157
LEU A 161
ALA A 125
LEU A  88
 None
 0.86A 2bxgB-5l2pA:
undetectable		 2bxgB-5l2pA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 6 TYR A 198
GLY A 278
TYR A 202
ASN A 277
 None
 1.24A 2g72A-5l2pA:
2.6		 2g72A-5l2pA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 12 LEU A 101
GLU A  94
ILE A 297
ILE A 244
PHE A 305
 None
 1.13A 2gj5A-5l2pA:
undetectable		 2gj5A-5l2pA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		3 / 3 LEU A 208
ASN A 207
ARG A 199
 None
 0.97A 2qhfA-5l2pA:
undetectable		 2qhfA-5l2pA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 12 HIS A  82
LEU A  38
ILE A  19
LEU A 116
TYR A 114
 None
 1.26A 2xkwA-5l2pA:
undetectable		 2xkwA-5l2pA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 12 THR A  93
ILE A  91
GLY A  84
GLY A  89
SER A  90
 None
 1.00A 2yvlA-5l2pA:
3.0		 2yvlA-5l2pA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 6 ALA A 243
SER A 273
THR A 271
VAL A 269
 None
 0.93A 3d2tB-5l2pA:
undetectable		 3d2tB-5l2pA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 6 PHE A 185
HIS A 281
ALA A  85
GLY A 213
 None
 1.01A 3dd1A-5l2pA:
undetectable		 3dd1A-5l2pA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 6 PHE A 185
HIS A 281
ALA A  85
GLY A 213
 None
 1.00A 3dd1B-5l2pA:
undetectable		 3dd1B-5l2pA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 6 PHE A 185
HIS A 281
ALA A  85
GLY A 213
 None
 1.00A 3ddsA-5l2pA:
3.1		 3ddsA-5l2pA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 6 PHE A 185
HIS A 281
ALA A  85
GLY A 213
 None
 1.01A 3ddsB-5l2pA:
3.1		 3ddsB-5l2pA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 6 PHE A 185
HIS A 281
ALA A  85
GLY A 213
 None
 1.00A 3ddwA-5l2pA:
undetectable		 3ddwA-5l2pA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 6 PHE A 185
HIS A 281
ALA A  85
GLY A 213
 None
 1.01A 3ddwB-5l2pA:
undetectable		 3ddwB-5l2pA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  89
ILE A 155
GLY A 154
HIS A  80
LEU A  38
 None
 0.96A 3eeyJ-5l2pA:
undetectable		 3eeyJ-5l2pA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_B_ADNB301_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 12 HIS A 281
GLY A  89
GLY A  83
ASN A  35
VAL A  34
 None
 1.28A 3f8wB-5l2pA:
undetectable		 3f8wB-5l2pA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 12 ASP A 113
GLU A  92
HIS A  80
GLY A  89
LEU A  38
 None
 1.31A 3j6pB-5l2pA:
3.8		 3j6pB-5l2pA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 12 LEU A 301
VAL A 186
PRO A 184
ALA A 178
LEU A 240
 None
 0.95A 3ku1H-5l2pA:
undetectable		 3ku1H-5l2pA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		3 / 3 TYR A 120
ASP A 128
ASP A 113
 None
 0.90A 3ou7B-5l2pA:
3.1		 3ou7B-5l2pA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 7 ALA A 243
SER A 273
THR A 271
VAL A 269
 None
 0.89A 3ozkB-5l2pA:
undetectable		 3ozkB-5l2pA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SM2_A_478A126_2
(GAG-PRO-POL
POLYPROTEIN)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 11 ALA A 282
GLY A  84
ALA A  85
TYR A  14
LEU A 284
 None
 1.03A 3sm2B-5l2pA:
undetectable		 3sm2B-5l2pA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 12 HIS A 281
ASP A 251
ILE A  97
GLY A  83
SER A 156
 None
 0.79A 3sueA-5l2pA:
undetectable		 3sueA-5l2pA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 12 HIS A 281
ASP A 251
ILE A  97
GLY A  83
SER A 156
 None
 0.75A 3sufB-5l2pA:
undetectable		 3sufB-5l2pA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A 213
ALA A 125
PHE A 185
ASN A 160
LEU A 161
 None
 1.08A 3vywB-5l2pA:
undetectable		 3vywB-5l2pA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A 159
GLY A 158
LEU A 116
GLU A  94
THR A 152
 None
 1.07A 4jkuB-5l2pA:
3.6		 4jkuB-5l2pA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A 159
GLY A 158
LEU A 116
GLU A  94
THR A 152
 None
 1.09A 4kadB-5l2pA:
4.0		 4kadB-5l2pA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 12 LEU A 208
ASP A 211
VAL A 210
PHE A 185
LEU A 232
 None
 1.22A 4nc3A-5l2pA:
undetectable		 4nc3A-5l2pA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_D_QI9D602_0
(CYTOCHROME P450 2D6)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 7 PHE A 153
GLU A  94
SER A  98
VAL A 182
 None
 0.96A 4wnvD-5l2pA:
undetectable		 4wnvD-5l2pA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP6_A_B40A601_1
(TRANSPORTER)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 5 ASP A 223
VAL A 210
ASP A 211
GLY A 213
 None
 1.25A 4xp6A-5l2pA:
0.0		 4xp6A-5l2pA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MM4_B_TA1B501_1
(TUBULIN BETA CHAIN)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 10 LEU A  62
HIS A  82
ALA A 157
SER A 156
THR A 124
 None
 1.28A 5mm4B-5l2pA:
undetectable		 5mm4B-5l2pA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 5 ALA A 151
VAL A 180
PHE A 305
ILE A 297
 None
 0.90A 5of1A-5l2pA:
undetectable		 5of1A-5l2pA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 5 ALA A 151
VAL A 180
PHE A 305
ILE A 297
 None
 0.91A 5of1B-5l2pA:
undetectable		 5of1B-5l2pA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGC_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 12 ASP A 113
GLU A  92
HIS A  80
GLY A  89
LEU A  38
 None
 1.29A 5ogcB-5l2pA:
4.5		 5ogcB-5l2pA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_2
(PROTEIN CYP51)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 6 PRO A 181
PRO A 231
LEU A 232
LEU A 167
 None
 1.15A 5tl8A-5l2pA:
undetectable		 5tl8A-5l2pA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 12 HIS A  82
LEU A  38
LEU A 161
LEU A 116
TYR A 114
 None
 1.24A 5y2oA-5l2pA:
undetectable		 5y2oA-5l2pA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		5 / 12 HIS A  82
LEU A  38
ILE A  19
LEU A 116
TYR A 114
 None
 1.18A 5ycpA-5l2pA:
undetectable		 5ycpA-5l2pA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5l2p ARYLESTERASE
(Sulfolobus
solfataricus) 		4 / 6 MET A  79
GLY A  76
ALA A 140
LEU A 143
 None
 1.02A 6fosA-5l2pA:
undetectable		 6fosA-5l2pA:
15.12