SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5l33'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P7R_A_NCTA440_1 (CYTOCHROME P450-CAM)	5l33	DENOVO NTF2 (synthetic construct)	4 / 7	THR A 30 VAL A 99 VAL A 25 ILE A 26	None	1.01A	1p7rA-5l33A: undetectable	1p7rA-5l33A: 13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DQT_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, ENDOTHELIAL)	5l33	DENOVO NTF2 (synthetic construct)	4 / 7	PHE A 72 GLU A 66 SER A 69 TRP A 70	None	1.20A	3dqtA-5l33A: undetectable 3dqtB-5l33A: undetectable	3dqtA-5l33A: 13.67 3dqtB-5l33A: 13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLR_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	5l33	DENOVO NTF2 (synthetic construct)	4 / 8	PHE A 72 GLU A 66 SER A 69 TRP A 70	None	1.17A	3nlrA-5l33A: undetectable 3nlrB-5l33A: undetectable	3nlrA-5l33A: 14.08 3nlrB-5l33A: 14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YBB_A_SAMA601_0 (TYPE I RESTRICTION-MODIFICA TION SYSTEM METHYLTRANSFERASE SUBUNIT)	5l33	DENOVO NTF2 (synthetic construct)	5 / 12	ALA A 7 GLY A 94 PRO A 1 LEU A 60 PHE A 72	None	1.13A	5ybbA-5l33A: undetectable	5ybbA-5l33A: 14.16

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1P7R_A_NCTA440_1","CYTOCHROME P450-CAM","5l33","DENOVO NTF2","synthetic construct",4,"THR A  30;VAL A  99;VAL A  25;ILE A  26","None","1.01A","1p7rA-5l33A:undetectable","1p7rA-5l33A:13.84"],["3DQT_B_H4BB760_1","NITRIC OXIDE SYNTHASE, ENDOTHELIAL;NITRIC OXIDE SYNTHASE, ENDOTHELIAL","5l33","DENOVO NTF2","synthetic construct",4,"PHE A  72;GLU A  66;SER A  69;TRP A  70","None","1.20A","3dqtA-5l33A:undetectable;3dqtB-5l33A:undetectable","3dqtA-5l33A:13.67;3dqtB-5l33A:13.67"],["3NLR_B_H4BB760_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","5l33","DENOVO NTF2","synthetic construct",4,"PHE A  72;GLU A  66;SER A  69;TRP A  70","None","1.17A","3nlrA-5l33A:undetectable;3nlrB-5l33A:undetectable","3nlrA-5l33A:14.08;3nlrB-5l33A:14.08"],["5YBB_A_SAMA601_0","TYPE I RESTRICTION-MODIFICATION SYSTEM METHYLTRANSFERASE SUBUNIT","5l33","DENOVO NTF2","synthetic construct",5,"ALA A   7;GLY A  94;PRO A   1;LEU A  60;PHE A  72","None","1.13A","5ybbA-5l33A:undetectable","5ybbA-5l33A:14.16"]]