SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5l39'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_1
(PROTEIN (HIV-1
PROTEASE))		 5l39 RMM MICROCOMPARTMENT
SHELL PROTEIN
MSM0275
(Mycolicibacteriu
m
smegmatis) 		5 / 10 LEU A  55
ALA A  90
ASP A  88
ILE A  38
VAL A  60
 None
 1.07A 1d4yA-5l39A:
undetectable		 1d4yA-5l39A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 5l39 RMM MICROCOMPARTMENT
SHELL PROTEIN
MSM0275
(Mycolicibacteriu
m
smegmatis) 		4 / 8 SER A 147
ILE A 150
GLU A  68
GLY A  72
 None
 0.94A 1meiA-5l39A:
undetectable		 1meiA-5l39A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 5l39 RMM MICROCOMPARTMENT
SHELL PROTEIN
MSM0275
(Mycolicibacteriu
m
smegmatis) 		5 / 12 VAL A  83
ILE A  10
ILE A  38
ILE A  25
ILE A 150
 None
 1.18A 1r5lA-5l39A:
undetectable		 1r5lA-5l39A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5l39 RMM MICROCOMPARTMENT
SHELL PROTEIN
MSM0275
(Mycolicibacteriu
m
smegmatis) 		5 / 10 ALA A 188
ALA A 191
GLN A 187
ALA A 160
ILE A  10
 None
 1.18A 2aclC-5l39A:
undetectable		 2aclC-5l39A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_2
(PROTEASE)		 5l39 RMM MICROCOMPARTMENT
SHELL PROTEIN
MSM0275
(Mycolicibacteriu
m
smegmatis) 		5 / 9 ALA A  90
ASP A  88
GLY A  95
VAL A  41
ILE A  39
 None
 1.22A 3em4B-5l39A:
undetectable		 3em4B-5l39A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_0
(16S RRNA METHYLASE)		 5l39 RMM MICROCOMPARTMENT
SHELL PROTEIN
MSM0275
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY A  63
GLY A  27
PRO A  30
ALA A  36
LEU A  65
 None
 0.94A 3p2kA-5l39A:
undetectable		 3p2kA-5l39A:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)		 5l39 RMM MICROCOMPARTMENT
SHELL PROTEIN
MSM0275
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY A  63
GLY A  27
PRO A  30
ALA A  36
LEU A  65
 None
 0.93A 3p2kD-5l39A:
undetectable		 3p2kD-5l39A:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA206_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 5l39 RMM MICROCOMPARTMENT
SHELL PROTEIN
MSM0275
(Mycolicibacteriu
m
smegmatis) 		4 / 4 ALA A 188
ALA A 191
ALA A 192
ALA A 195
 None
 0.13A 4oadA-5l39A:
undetectable		 4oadA-5l39A:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l39 RMM MICROCOMPARTMENT
SHELL PROTEIN
MSM0275
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLN A  70
ALA A 149
GLY A 174
THR A 173
ALA A 144
 None
 1.02A 4qvpH-5l39A:
undetectable
4qvpI-5l39A:
undetectable		 4qvpH-5l39A:
22.05
4qvpI-5l39A:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l39 RMM MICROCOMPARTMENT
SHELL PROTEIN
MSM0275
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLN A  70
ALA A 149
GLY A 174
THR A 173
ALA A 144
 None
 1.02A 4qvpV-5l39A:
undetectable
4qvpW-5l39A:
undetectable		 4qvpV-5l39A:
22.05
4qvpW-5l39A:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5l39 RMM MICROCOMPARTMENT
SHELL PROTEIN
MSM0275
(Mycolicibacteriu
m
smegmatis) 		5 / 11 GLN A  70
ALA A 149
GLY A 174
THR A 173
ALA A 144
 None
 1.14A 4qvvH-5l39A:
undetectable		 4qvvH-5l39A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5l39 RMM MICROCOMPARTMENT
SHELL PROTEIN
MSM0275
(Mycolicibacteriu
m
smegmatis) 		5 / 11 GLN A  70
ALA A 149
GLY A 174
THR A 173
ALA A 144
 None
 1.13A 4qvvV-5l39A:
undetectable		 4qvvV-5l39A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5l39 RMM MICROCOMPARTMENT
SHELL PROTEIN
MSM0275
(Mycolicibacteriu
m
smegmatis) 		5 / 11 GLN A  70
ALA A 149
GLY A 174
THR A 173
ALA A 144
 None
 1.14A 4qvyH-5l39A:
undetectable		 4qvyH-5l39A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l39 RMM MICROCOMPARTMENT
SHELL PROTEIN
MSM0275
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLN A  70
ALA A 149
GLY A 174
THR A 173
ALA A 144
 None
 1.14A 4qvyV-5l39A:
undetectable
4qvyW-5l39A:
undetectable		 4qvyV-5l39A:
22.05
4qvyW-5l39A:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l39 RMM MICROCOMPARTMENT
SHELL PROTEIN
MSM0275
(Mycolicibacteriu
m
smegmatis) 		5 / 11 GLN A  70
ALA A 149
GLY A 174
THR A 173
ALA A 144
 None
 1.09A 4qw0H-5l39A:
undetectable
4qw0I-5l39A:
undetectable		 4qw0H-5l39A:
22.05
4qw0I-5l39A:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l39 RMM MICROCOMPARTMENT
SHELL PROTEIN
MSM0275
(Mycolicibacteriu
m
smegmatis) 		5 / 11 GLN A  70
ALA A 149
GLY A 174
THR A 173
ALA A 144
 None
 1.09A 4qw0V-5l39A:
undetectable
4qw0W-5l39A:
undetectable		 4qw0V-5l39A:
22.05
4qw0W-5l39A:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l39 RMM MICROCOMPARTMENT
SHELL PROTEIN
MSM0275
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLN A  70
ALA A 149
GLY A 174
THR A 173
ALA A 144
 None
 1.09A 4qw1H-5l39A:
undetectable
4qw1I-5l39A:
undetectable		 4qw1H-5l39A:
22.05
4qw1I-5l39A:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l39 RMM MICROCOMPARTMENT
SHELL PROTEIN
MSM0275
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLN A  70
ALA A 149
GLY A 174
THR A 173
ALA A 144
 None
 1.09A 4qw1V-5l39A:
undetectable
4qw1W-5l39A:
undetectable		 4qw1V-5l39A:
22.05
4qw1W-5l39A:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l39 RMM MICROCOMPARTMENT
SHELL PROTEIN
MSM0275
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLN A  70
ALA A 149
GLY A 174
THR A 173
ALA A 144
 None
 1.05A 5cz7V-5l39A:
undetectable
5cz7W-5l39A:
undetectable		 5cz7V-5l39A:
22.05
5cz7W-5l39A:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5l39 RMM MICROCOMPARTMENT
SHELL PROTEIN
MSM0275
(Mycolicibacteriu
m
smegmatis) 		5 / 11 GLN A  70
ALA A 149
GLY A 174
THR A 173
ALA A 144
 None
 1.05A 5d0xV-5l39A:
undetectable		 5d0xV-5l39A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNU_A_BEZA319_0
(SHKAI2IB)		 5l39 RMM MICROCOMPARTMENT
SHELL PROTEIN
MSM0275
(Mycolicibacteriu
m
smegmatis) 		4 / 5 GLN A  37
HIS A  77
ILE A  38
ILE A  64
 None
 1.14A 5dnuA-5l39A:
undetectable		 5dnuA-5l39A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNV_A_BEZA304_0
(SHKAI2IB)		 5l39 RMM MICROCOMPARTMENT
SHELL PROTEIN
MSM0275
(Mycolicibacteriu
m
smegmatis) 		4 / 5 GLN A  37
HIS A  77
ILE A  38
ILE A  64
 None
 1.12A 5dnvA-5l39A:
undetectable		 5dnvA-5l39A:
21.40