SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5l3r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 5 LEU B 320
LEU B 317
SER B 331
GLY B 326
None
0.75A 1a4lC-5l3rB:
undetectable
1a4lC-5l3rB:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 12 ASP B 108
LEU A 325
SER A 120
LEU A 322
THR A 323
None
None
None
None
GCP  A 401 ( 4.8A)
1.12A 1jffB-5l3rB:
undetectable
1jffB-5l3rB:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_B_T44B602_1
(TRANSTHYRETIN)
5l3r SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 7 GLU A 303
ALA A 333
LEU A 322
ALA A 320
None
1.02A 1sn0B-5l3rA:
undetectable
1sn0D-5l3rA:
undetectable
1sn0B-5l3rA:
19.93
1sn0D-5l3rA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XPQ_C_SPMC921_1
(FMS1 PROTEIN)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 11 ASP A 328
ASN B 298
LEU B 315
LEU B 289
CYH B 328
None
1.43A 1xpqC-5l3rA:
undetectable
1xpqC-5l3rA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 7 THR B 255
LEU B 236
VAL B 276
VAL B 310
None
1.00A 1yrcA-5l3rB:
undetectable
1yrcA-5l3rB:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 7 THR B 255
LEU B 236
VAL B 276
VAL B 310
None
1.05A 1yrdA-5l3rB:
undetectable
1yrdA-5l3rB:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 6 THR B 255
LEU B 236
VAL B 276
VAL B 310
None
0.99A 2feuA-5l3rB:
undetectable
2feuA-5l3rB:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 7 THR B 255
LEU B 236
VAL B 276
VAL B 310
None
1.00A 2feuB-5l3rB:
undetectable
2feuB-5l3rB:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA702_0
(FERROCHELATASE)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 7 MET B 299
ARG B 325
LEU B 320
MET B 147
None
1.07A 2hrcA-5l3rB:
undetectable
2hrcA-5l3rB:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 12 ASP B 108
LEU A 325
SER A 120
LEU A 322
THR A 323
None
None
None
None
GCP  A 401 ( 4.8A)
1.12A 2hxfB-5l3rB:
undetectable
2hxfB-5l3rB:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 12 ASP B 108
LEU A 325
SER A 120
LEU A 322
THR A 323
None
None
None
None
GCP  A 401 ( 4.8A)
1.12A 2hxhB-5l3rB:
undetectable
2hxhB-5l3rB:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_B_ADNB2005_1
(TRYPTOPHAN
HALOGENASE)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 7 GLY A 301
ASP B 292
VAL A 296
LEU A 307
None
0.83A 2oa1B-5l3rA:
undetectable
2oa1B-5l3rA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_B_ADNB2005_1
(TRYPTOPHAN
HALOGENASE)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 7 GLY A 301
GLY B 296
ASP B 292
VAL A 296
None
0.82A 2oa1B-5l3rA:
undetectable
2oa1B-5l3rA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 12 ASP B 108
LEU A 325
SER A 120
LEU A 322
THR A 323
None
None
None
None
GCP  A 401 ( 4.8A)
1.12A 2p4nB-5l3rB:
undetectable
2p4nB-5l3rB:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 12 ASP B 108
LEU A 325
SER A 120
LEU A 322
THR A 323
None
None
None
None
GCP  A 401 ( 4.8A)
1.12A 2wbeB-5l3rB:
undetectable
2wbeB-5l3rB:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_A_SAMA298_0
(PUTATIVE
MODIFICATION
METHYLASE)
5l3r SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 12 ALA A 334
SER A 167
GLY A 319
THR A 318
VAL A 295
None
1.24A 2zifA-5l3rA:
undetectable
2zifA-5l3rA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 6 THR B 255
LEU B 236
VAL B 276
VAL B 310
None
1.08A 2zuiA-5l3rB:
undetectable
2zuiA-5l3rB:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 7 THR B 255
LEU B 236
VAL B 276
VAL B 310
None
1.02A 2zwtA-5l3rB:
undetectable
2zwtA-5l3rB:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 7 THR B 255
LEU B 236
VAL B 276
VAL B 310
None
1.02A 2zwuA-5l3rB:
undetectable
2zwuA-5l3rB:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)
5l3r SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana;
Arabidopsis
thaliana)
5 / 12 LEU A 115
PHE B 109
VAL B 144
LEU B 104
PHE B 365
None
1.23A 2zzmA-5l3rA:
undetectable
2zzmA-5l3rA:
25.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 12 ASP B 108
LEU A 325
SER A 120
LEU A 322
THR A 323
None
None
None
None
GCP  A 401 ( 4.8A)
1.12A 3dcoB-5l3rB:
undetectable
3dcoB-5l3rB:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 12 ASP B 108
LEU A 325
SER A 120
LEU A 322
THR A 323
None
None
None
None
GCP  A 401 ( 4.8A)
1.12A 3edlB-5l3rB:
undetectable
3edlB-5l3rB:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 7 THR B 255
LEU B 236
VAL B 276
VAL B 310
None
0.96A 3fwfA-5l3rB:
undetectable
3fwfA-5l3rB:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 7 THR B 255
LEU B 236
VAL B 276
VAL B 310
None
0.95A 3fwfB-5l3rB:
undetectable
3fwfB-5l3rB:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 7 THR B 255
LEU B 236
VAL B 276
VAL B 310
None
1.01A 3fwjA-5l3rB:
undetectable
3fwjA-5l3rB:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 12 ILE B 312
VAL B 340
MET B 299
VAL B 329
VAL B 332
None
1.19A 3iw1A-5l3rB:
undetectable
3iw1A-5l3rB:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 12 ASP B 108
LEU A 325
SER A 120
LEU A 322
THR A 323
None
None
None
None
GCP  A 401 ( 4.8A)
1.09A 3iz0B-5l3rB:
undetectable
3iz0B-5l3rB:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 7 THR B 255
LEU B 236
VAL B 276
VAL B 310
None
0.93A 3l63A-5l3rB:
undetectable
3l63A-5l3rB:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 5 ARG B 120
LEU B 100
ILE B 364
PHE B 365
None
1.23A 3ln1D-5l3rB:
undetectable
3ln1D-5l3rB:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_1
(FIV PROTEASE)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 10 LEU B 289
ILE B 343
VAL B 340
GLY B 327
LEU B 315
None
0.92A 3ogqA-5l3rB:
undetectable
3ogqA-5l3rB:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 7 THR B 234
VAL B 235
LEU B 236
ALA B 275
None
1.03A 3uniA-5l3rB:
1.5
3uniA-5l3rB:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)
5l3r SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 9 ARG A 269
GLY A 183
LEU A 181
LEU A 294
ILE A 321
None
1.34A 3wdmA-5l3rA:
undetectable
3wdmA-5l3rA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 7 THR B 255
LEU B 236
VAL B 276
VAL B 310
None
1.00A 3wrhA-5l3rB:
undetectable
3wrhA-5l3rB:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 7 THR B 255
LEU B 236
VAL B 276
VAL B 310
None
1.01A 3wrjA-5l3rB:
undetectable
3wrjA-5l3rB:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 7 THR B 255
LEU B 236
VAL B 276
VAL B 310
None
0.97A 3wrlA-5l3rB:
undetectable
3wrlA-5l3rB:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 7 THR B 255
LEU B 236
VAL B 276
VAL B 310
None
0.94A 3wrlE-5l3rB:
undetectable
3wrlE-5l3rB:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 7 THR B 255
LEU B 236
VAL B 276
VAL B 310
None
0.98A 3wrmA-5l3rB:
undetectable
3wrmA-5l3rB:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 7 THR B 255
LEU B 236
VAL B 276
VAL B 310
None
1.00A 3wrmF-5l3rB:
undetectable
3wrmF-5l3rB:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 7 GLY B 314
THR B 313
ILE B 312
THR B 255
None
0.87A 4acaC-5l3rB:
8.3
4acaC-5l3rB:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)
5l3r SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 12 GLY A 183
GLY A 268
ASP A 265
LEU A 270
VAL A 187
None
GCP  A 401 (-3.4A)
MG  A 402 (-3.9A)
GCP  B 401 ( 4.9A)
GCP  A 401 (-4.2A)
1.05A 4fr0A-5l3rA:
2.3
4fr0A-5l3rA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IOM_A_FOLA608_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 7 ALA B 303
PRO B 301
LEU B 291
LEU B 289
None
1.07A 4iomA-5l3rB:
11.8
4iomA-5l3rB:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 7 SER B 331
ASP B 292
GLY A 301
GLU A 303
None
0.96A 4koeA-5l3rB:
undetectable
4koeB-5l3rB:
undetectable
4koeD-5l3rB:
4.0
4koeA-5l3rB:
19.76
4koeB-5l3rB:
19.76
4koeD-5l3rB:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)
5l3r SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana;
Arabidopsis
thaliana)
5 / 12 ASN B 294
GLY B 346
ASP B 321
GLN A 185
THR B 179
None
GCP  B 401 (-3.4A)
GCP  B 401 (-3.2A)
GCP  B 401 ( 3.6A)
GCP  B 401 (-3.6A)
1.19A 4o5fA-5l3rB:
undetectable
4o5fB-5l3rB:
undetectable
4o5fA-5l3rB:
22.15
4o5fB-5l3rB:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)
5l3r SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana;
Arabidopsis
thaliana)
5 / 12 GLN A 185
THR B 179
ASN B 294
GLY B 346
ASP B 321
GCP  B 401 ( 3.6A)
GCP  B 401 (-3.6A)
None
GCP  B 401 (-3.4A)
GCP  B 401 (-3.2A)
1.18A 4o5fA-5l3rA:
undetectable
4o5fB-5l3rA:
undetectable
4o5fA-5l3rA:
25.46
4o5fB-5l3rA:
25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A505_1
(HOMOSPERMIDINE
SYNTHASE)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 12 ALA A 219
PRO A 217
GLU B 347
ASP A 265
THR A 190
MG  A 402 ( 3.7A)
None
GCP  B 401 (-3.5A)
MG  A 402 (-3.9A)
MG  A 402 ( 3.5A)
1.45A 4xqeA-5l3rA:
2.7
4xqeA-5l3rA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B504_1
(HOMOSPERMIDINE
SYNTHASE)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 12 ALA A 219
PRO A 217
GLU B 347
ASP A 265
THR A 190
MG  A 402 ( 3.7A)
None
GCP  B 401 (-3.5A)
MG  A 402 (-3.9A)
MG  A 402 ( 3.5A)
1.44A 4xqeB-5l3rA:
2.8
4xqeB-5l3rA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XRG_B_AG2B502_1
(HOMOSPERMIDINE
SYNTHASE)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 12 ALA A 219
PRO A 217
GLU B 347
ASP A 265
THR A 190
MG  A 402 ( 3.7A)
None
GCP  B 401 (-3.5A)
MG  A 402 (-3.9A)
MG  A 402 ( 3.5A)
1.45A 4xrgB-5l3rA:
2.6
4xrgB-5l3rA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 11 GLY B 327
ALA B 103
ILE B  81
LEU B 140
ILE B 113
None
0.95A 4xumB-5l3rB:
undetectable
4xumB-5l3rB:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)
5l3r SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana;
Arabidopsis
thaliana)
4 / 6 GLU A 303
GLY A 301
GLY B 296
ASP B 108
None
0.87A 5a06D-5l3rA:
2.6
5a06D-5l3rA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_A_PAUA302_0
(TYPE III
PANTOTHENATE KINASE)
5l3r SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana;
Arabidopsis
thaliana)
5 / 12 ASN B 294
GLY B 346
ASP B 321
GLN A 185
THR B 179
None
GCP  B 401 (-3.4A)
GCP  B 401 (-3.2A)
GCP  B 401 ( 3.6A)
GCP  B 401 (-3.6A)
1.12A 5b8hA-5l3rB:
2.1
5b8hB-5l3rB:
undetectable
5b8hA-5l3rB:
23.17
5b8hB-5l3rB:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)
5l3r SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana;
Arabidopsis
thaliana)
5 / 12 GLN A 185
THR B 179
ASN B 294
GLY B 346
ASP B 321
GCP  B 401 ( 3.6A)
GCP  B 401 (-3.6A)
None
GCP  B 401 (-3.4A)
GCP  B 401 (-3.2A)
1.19A 5b8hA-5l3rA:
undetectable
5b8hB-5l3rA:
undetectable
5b8hA-5l3rA:
24.70
5b8hB-5l3rA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)
5l3r SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 11 ASP A 265
LEU A 180
ILE A 246
ALA A 219
ILE A 220
MG  A 402 (-3.9A)
None
None
MG  A 402 ( 3.7A)
None
0.99A 5d75A-5l3rA:
undetectable
5d75A-5l3rA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 12 ASP B 108
LEU A 325
SER A 120
LEU A 322
THR A 323
None
None
None
None
GCP  A 401 ( 4.8A)
1.07A 5hnwB-5l3rB:
undetectable
5hnwB-5l3rB:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 12 ASP B 108
LEU A 325
SER A 120
LEU A 322
THR A 323
None
None
None
None
GCP  A 401 ( 4.8A)
1.08A 5hnyB-5l3rB:
undetectable
5hnyB-5l3rB:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_C_SAMC501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 12 ILE B 343
GLY B 344
THR B 179
SER B 180
LEU B 315
None
GCP  B 401 (-3.5A)
GCP  B 401 (-3.6A)
GCP  B 401 ( 4.9A)
None
1.21A 5nfjC-5l3rB:
undetectable
5nfjC-5l3rB:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
3 / 3 CYH B 328
MET B 299
ASN B 298
None
1.26A 5qh8A-5l3rB:
undetectable
5qh8A-5l3rB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 8 GLY B 344
GLU B 347
GLN B 302
ASP B 292
GCP  B 401 (-3.5A)
GCP  B 401 (-3.5A)
None
None
1.05A 5vlmD-5l3rB:
3.0
5vlmD-5l3rB:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 7 THR B 255
LEU B 236
VAL B 276
VAL B 310
None
1.02A 5wk9A-5l3rB:
undetectable
5wk9A-5l3rB:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 12 VAL B 332
VAL B 329
GLY B 175
THR A 300
GLY A 301
None
None
GCP  B 401 (-4.1A)
None
None
1.14A 6brdC-5l3rB:
undetectable
6brdC-5l3rB:
13.59