SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5l51'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FPQ_A_SAMA1699_0
(ISOLIQUIRITIGENIN
2'-O-METHYLTRANSFERA
SE)		 5l51 (-)-MENTHONE:(+)-NEO
MENTHOL REDUCTASE
(Mentha
x
piperita) 		5 / 10 GLY A  26
ASN A  22
LEU A  33
VAL A  40
ALA A 103
 None
 1.38A 1fpqA-5l51A:
6.2		 1fpqA-5l51A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5l51 (-)-MENTHONE:(+)-NEO
MENTHOL REDUCTASE
(Mentha
x
piperita) 		5 / 12 ILE A  29
ASN A  22
LEU A  33
ALA A  34
VAL A 186
 None
 0.79A 1xdkA-5l51A:
undetectable		 1xdkA-5l51A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5l51 (-)-MENTHONE:(+)-NEO
MENTHOL REDUCTASE
(Mentha
x
piperita) 		5 / 12 ILE A  29
LEU A  42
LEU A  33
ALA A  34
VAL A 186
 None
 0.93A 1xlsA-5l51A:
undetectable		 1xlsA-5l51A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5l51 (-)-MENTHONE:(+)-NEO
MENTHOL REDUCTASE
(Mentha
x
piperita) 		5 / 12 ILE A  29
LEU A  42
LEU A  33
ALA A  34
VAL A 186
 None
 0.93A 1xlsB-5l51A:
undetectable		 1xlsB-5l51A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5l51 (-)-MENTHONE:(+)-NEO
MENTHOL REDUCTASE
(Mentha
x
piperita) 		5 / 12 ILE A  29
LEU A  42
LEU A  33
ALA A  34
VAL A 186
 None
 0.93A 1xlsC-5l51A:
undetectable		 1xlsC-5l51A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5l51 (-)-MENTHONE:(+)-NEO
MENTHOL REDUCTASE
(Mentha
x
piperita) 		5 / 12 ILE A  29
LEU A  42
LEU A  33
ALA A  34
VAL A 186
 None
 0.93A 1xlsD-5l51A:
undetectable		 1xlsD-5l51A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 5l51 (-)-MENTHONE:(+)-NEO
MENTHOL REDUCTASE
(Mentha
x
piperita) 		4 / 6 TRP A 237
GLY A 203
PHE A 205
SER A 206
 None
 1.18A 2a3cA-5l51A:
3.4		 2a3cA-5l51A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		 5l51 (-)-MENTHONE:(+)-NEO
MENTHOL REDUCTASE
(Mentha
x
piperita) 		4 / 6 TRP A 237
GLY A 203
PHE A 205
SER A 206
 None
 1.10A 2a3cB-5l51A:
3.3		 2a3cB-5l51A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5l51 (-)-MENTHONE:(+)-NEO
MENTHOL REDUCTASE
(Mentha
x
piperita) 		5 / 12 GLY A  20
ARG A  45
ASP A  75
ASN A 102
ALA A 103
 None
 0.96A 2bm9E-5l51A:
5.4		 2bm9E-5l51A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_0
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 5l51 (-)-MENTHONE:(+)-NEO
MENTHOL REDUCTASE
(Mentha
x
piperita) 		5 / 12 ALA A  53
GLY A  20
GLY A  24
ALA A  43
LEU A  85
 None
 1.05A 2plwA-5l51A:
3.0		 2plwA-5l51A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_G_CPFG1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 5l51 (-)-MENTHONE:(+)-NEO
MENTHOL REDUCTASE
(Mentha
x
piperita) 		3 / 3 ARG A  49
GLY A  50
SER A  81
 None
 0.57A 2xctB-5l51A:
2.3		 2xctB-5l51A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5l51 (-)-MENTHONE:(+)-NEO
MENTHOL REDUCTASE
(Mentha
x
piperita) 		5 / 12 ILE A  29
ASN A  22
LEU A  33
ALA A  34
VAL A 186
 None
 0.98A 3dzyA-5l51A:
undetectable		 3dzyA-5l51A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5l51 (-)-MENTHONE:(+)-NEO
MENTHOL REDUCTASE
(Mentha
x
piperita) 		5 / 10 ILE A 172
SER A 191
ARG A 256
ALA A 253
ALA A 269
 None
 1.40A 3lw5B-5l51A:
undetectable		 3lw5B-5l51A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 5l51 (-)-MENTHONE:(+)-NEO
MENTHOL REDUCTASE
(Mentha
x
piperita) 		4 / 7 ASN A 185
ALA A 269
ARG A 266
ALA A 259
 None
 1.10A 3twpB-5l51A:
3.5		 3twpB-5l51A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)		 5l51 (-)-MENTHONE:(+)-NEO
MENTHOL REDUCTASE
(Mentha
x
piperita) 		4 / 6 VAL A  17
LEU A  96
ILE A  89
VAL A 167
 None
 0.94A 4a9kA-5l51A:
undetectable		 4a9kA-5l51A:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 5l51 (-)-MENTHONE:(+)-NEO
MENTHOL REDUCTASE
(Mentha
x
piperita) 		5 / 12 ILE A  38
ALA A 299
THR A  19
LEU A 171
LEU A  96
 None
 1.07A 4qzuC-5l51A:
undetectable		 4qzuC-5l51A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5l51 (-)-MENTHONE:(+)-NEO
MENTHOL REDUCTASE
(Mentha
x
piperita) 		5 / 11 ILE A  29
LEU A  42
LEU A  33
ALA A  34
VAL A 186
 None
 0.99A 5ji0A-5l51A:
undetectable		 5ji0A-5l51A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 5l51 (-)-MENTHONE:(+)-NEO
MENTHOL REDUCTASE
(Mentha
x
piperita) 		4 / 4 ASN A 185
SER A 307
ALA A 269
VAL A 270
 None
 1.20A 5nm5A-5l51A:
6.6		 5nm5A-5l51A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 5l51 (-)-MENTHONE:(+)-NEO
MENTHOL REDUCTASE
(Mentha
x
piperita) 		4 / 5 LEU A 211
TYR A 254
LEU A 216
GLU A 217
 None
 1.33A 5weaA-5l51A:
2.2		 5weaA-5l51A:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F32_B_ACTB602_0
(AMINE OXIDASE LKCE)		 5l51 (-)-MENTHONE:(+)-NEO
MENTHOL REDUCTASE
(Mentha
x
piperita) 		4 / 6 ASN A 185
TYR A 254
VAL A 167
THR A 168
 None
 1.42A 6f32B-5l51A:
4.4		 6f32B-5l51A:
21.98