SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5l56'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 5l56 PLEXIN-A1
(Mus
musculus) 		4 / 4 THR A 187
PRO A 197
THR A 198
PRO A 188
 None
 1.33A 1dsdC-5l56A:
undetectable		 1dsdC-5l56A:
1.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 5l56 PLEXIN-A1
(Mus
musculus) 		4 / 4 THR A 198
PRO A 188
THR A 187
PRO A 197
 None
 1.26A 1dsdC-5l56A:
undetectable		 1dsdC-5l56A:
1.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 5l56 PLEXIN-A1
(Mus
musculus) 		4 / 4 THR A 187
PRO A 197
THR A 198
PRO A 188
 None
 1.33A 1dsdC-5l56A:
undetectable		 1dsdC-5l56A:
1.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 5l56 PLEXIN-A1
(Mus
musculus) 		4 / 4 THR A 198
PRO A 188
THR A 187
PRO A 197
 None
 1.26A 1dsdC-5l56A:
undetectable		 1dsdC-5l56A:
1.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5l56 PLEXIN-A1
(Mus
musculus) 		4 / 7 SER A 130
GLY A  64
HIS A  51
ILE A  69
 None
 0.91A 1gtnF-5l56A:
undetectable
1gtnG-5l56A:
undetectable		 1gtnF-5l56A:
7.64
1gtnG-5l56A:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 5l56 PLEXIN-A1
(Mus
musculus) 		4 / 6 LEU A 580
PHE A 654
TYR A 657
VAL A 652
 None
 1.23A 1ibgH-5l56A:
3.5		 1ibgH-5l56A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5l56 PLEXIN-A1
(Mus
musculus) 		5 / 11 SER A 606
LEU A 590
VAL A 587
PHE A 649
VAL A 594
 None
 1.17A 1q23J-5l56A:
undetectable		 1q23J-5l56A:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5l56 PLEXIN-A1
(Mus
musculus) 		5 / 12 LEU A 432
ALA A 313
LEU A 335
LEU A 424
PHE A 339
 None
 1.20A 1s9pB-5l56A:
undetectable		 1s9pB-5l56A:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA11_1
(CES1 PROTEIN)		 5l56 PLEXIN-A1
(Mus
musculus) 		4 / 8 PRO A1176
GLY A1060
LEU A1184
PRO A1053
 None
 0.83A 1ya4A-5l56A:
undetectable		 1ya4A-5l56A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB1283_1
(CES1 PROTEIN)		 5l56 PLEXIN-A1
(Mus
musculus) 		4 / 7 PRO A1176
GLY A1060
LEU A1184
PRO A1053
 None
 0.83A 1ya4B-5l56A:
undetectable		 1ya4B-5l56A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 5l56 PLEXIN-A1
(Mus
musculus) 		4 / 6 GLU A 352
TYR A 307
ASP A 427
PHE A 425
 None
 1.37A 2a3bB-5l56A:
undetectable		 2a3bB-5l56A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 5l56 PLEXIN-A1
(Mus
musculus) 		5 / 12 LEU A 459
ASN A 464
LEU A 462
ALA A 463
LEU A 357
 None
 1.30A 2aa5B-5l56A:
undetectable		 2aa5B-5l56A:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5l56 PLEXIN-A1
(Mus
musculus) 		4 / 6 ARG A 124
GLN A 137
PHE A 214
LEU A 204
 None
 1.16A 3ablP-5l56A:
undetectable
3ablW-5l56A:
undetectable		 3ablP-5l56A:
12.46
3ablW-5l56A:
4.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW1_A_STIA233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5l56 PLEXIN-A1
(Mus
musculus) 		5 / 10 GLY A1223
GLY A1061
THR A1062
ASN A1090
ILE A1057
 None
 1.40A 3fw1A-5l56A:
undetectable		 3fw1A-5l56A:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LK0_D_Z80D92_1
(PROTEIN S100-B)		 5l56 PLEXIN-A1
(Mus
musculus) 		3 / 3 HIS A 899
PHE A 954
PHE A 956
 None
 0.72A 3lk0D-5l56A:
undetectable		 3lk0D-5l56A:
5.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 5l56 PLEXIN-A1
(Mus
musculus) 		4 / 7 TYR A  62
ASN A 123
LEU A 141
ASP A 142
 None
 1.25A 3lslA-5l56A:
undetectable
3lslD-5l56A:
undetectable		 3lslA-5l56A:
12.11
3lslD-5l56A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 5l56 PLEXIN-A1
(Mus
musculus) 		4 / 7 TYR A  62
ASN A 123
LEU A 141
ASP A 142
 None
 1.15A 3lslA-5l56A:
undetectable
3lslD-5l56A:
undetectable		 3lslA-5l56A:
12.11
3lslD-5l56A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)		 5l56 PLEXIN-A1
(Mus
musculus) 		4 / 6 TYR A  62
ASN A 123
LEU A 141
ASP A 142
 None
 1.15A 3lslG-5l56A:
undetectable		 3lslG-5l56A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_1
(ENDOTHIAPEPSIN)		 5l56 PLEXIN-A1
(Mus
musculus) 		5 / 10 ILE A 172
ILE A 242
TYR A 244
LEU A 199
ILE A 298
 None
 1.24A 3prsA-5l56A:
undetectable		 3prsA-5l56A:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 5l56 PLEXIN-A1
(Mus
musculus) 		4 / 7 HIS A 156
GLU A 155
PHE A 216
PRO A 197
 None
 1.12A 3ql6A-5l56A:
undetectable		 3ql6A-5l56A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGL_A_GLYA301_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 5l56 PLEXIN-A1
(Mus
musculus) 		5 / 8 ALA A 986
GLY A 872
THR A 871
ARG A1004
THR A 878
 None
 1.49A 3rglA-5l56A:
undetectable		 3rglA-5l56A:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)		 5l56 PLEXIN-A1
(Mus
musculus) 		5 / 12 GLY A1222
GLY A1060
GLU A1225
ALA A1221
TYR A1186
 None
 1.24A 3sxjA-5l56A:
undetectable		 3sxjA-5l56A:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)		 5l56 PLEXIN-A1
(Mus
musculus) 		5 / 12 GLY A1222
GLY A1060
GLU A1225
ALA A1221
TYR A1186
 None
 1.25A 3sxjB-5l56A:
undetectable		 3sxjB-5l56A:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_C_SAMC300_0
(PUTATIVE
METHYLTRANSFERASE)		 5l56 PLEXIN-A1
(Mus
musculus) 		5 / 12 GLY A1222
GLY A1060
GLU A1225
ALA A1221
TYR A1186
 None
 1.24A 3t7sC-5l56A:
undetectable		 3t7sC-5l56A:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 5l56 PLEXIN-A1
(Mus
musculus) 		5 / 12 VAL A 426
THR A 422
PRO A 423
TYR A 307
VAL A 435
 None
 1.37A 4eb6B-5l56A:
undetectable
4eb6C-5l56A:
undetectable		 4eb6B-5l56A:
16.68
4eb6C-5l56A:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5l56 PLEXIN-A1
(Mus
musculus) 		4 / 6 ILE A 484
THR A 433
SER A 452
ASP A 527
 None
 1.14A 4iaqA-5l56A:
undetectable		 4iaqA-5l56A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5l56 PLEXIN-A1
(Mus
musculus) 		4 / 8 VAL A 254
TYR A 256
LEU A 115
LEU A 117
 None
 1.08A 4jtrA-5l56A:
undetectable		 4jtrA-5l56A:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)		 5l56 PLEXIN-A1
(Mus
musculus) 		5 / 12 LEU A 535
LEU A 590
ALA A 584
VAL A 562
ALA A 650
 None
 1.07A 4x1yD-5l56A:
undetectable		 4x1yD-5l56A:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5l56 PLEXIN-A1
(Mus
musculus) 		5 / 12 ALA A1104
LEU A1064
GLY A 969
THR A 975
MET A1128
 None
 0.86A 5eshA-5l56A:
undetectable		 5eshA-5l56A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 5l56 PLEXIN-A1
(Mus
musculus) 		4 / 6 GLY A 186
THR A 187
SER A 200
VAL A 185
 None
 1.06A 5ewuA-5l56A:
undetectable		 5ewuA-5l56A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 5l56 PLEXIN-A1
(Mus
musculus) 		5 / 12 ASP A 527
ALA A 437
PHE A 336
THR A 422
LEU A 322
 None
 1.46A 5m54B-5l56A:
undetectable		 5m54B-5l56A:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5l56 PLEXIN-A1
(Mus
musculus) 		5 / 9 ASP A1108
ILE A1057
PHE A1224
SER A1106
GLY A1061
 None
 1.18A 6awoA-5l56A:
undetectable		 6awoA-5l56A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWP_A_FVXA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5l56 PLEXIN-A1
(Mus
musculus) 		5 / 9 ASP A1108
ILE A1057
PHE A1224
SER A1106
GLY A1061
 None
 1.21A 6awpA-5l56A:
undetectable		 6awpA-5l56A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5l56 PLEXIN-A1
(Mus
musculus) 		5 / 9 ASP A1108
ILE A1057
PHE A1224
SER A1106
GLY A1061
 None
 1.18A 6awqA-5l56A:
undetectable		 6awqA-5l56A:
18.11