SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5l5w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 12 TRP K 104
GLY K 103
ALA K   5
GLY K 183
HIS K 178
 None
 1.11A 1kiaB-5l5wK:
undetectable		 1kiaB-5l5wK:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 11 THR K   1
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.84A 2f162-5l5wK:
28.7		 2f162-5l5wK:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   2
THR K   1
SER K 173
GLY K 172
ALA K 164
 None
 0.94A 2f162-5l5wK:
28.7		 2f162-5l5wK:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 11 THR K   1
ALA K  27
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.66A 2f16H-5l5wK:
29.0
2f16I-5l5wK:
25.4		 2f16H-5l5wK:
29.91
2f16I-5l5wK:
23.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 10 ALA K  20
ALA K  22
ALA K  27
VAL K  31
GLY K  48
 None
 0.75A 2f16K-5l5wK:
37.1
2f16L-5l5wK:
23.6		 2f16K-5l5wK:
82.55
2f16L-5l5wK:
23.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		9 / 10 THR K   1
ALA K  20
THR K  21
ALA K  22
ALA K  27
VAL K  31
LYS K  33
GLY K  47
ALA K  49
 None
 0.72A 2f16K-5l5wK:
37.1
2f16L-5l5wK:
23.6		 2f16K-5l5wK:
82.55
2f16L-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 11 THR K   1
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.83A 2f16N-5l5wK:
28.7		 2f16N-5l5wK:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   2
THR K   1
SER K 173
GLY K 172
ALA K 164
 None
 0.93A 2f16N-5l5wK:
28.7		 2f16N-5l5wK:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 11 THR K   1
ALA K  27
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.68A 2f16V-5l5wK:
29.0
2f16W-5l5wK:
25.4		 2f16V-5l5wK:
29.91
2f16W-5l5wK:
23.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 10 ALA K  20
ALA K  22
ALA K  27
VAL K  31
GLY K  48
 None
 0.75A 2f16Y-5l5wK:
23.7
2f16Z-5l5wK:
23.4		 2f16Y-5l5wK:
82.55
2f16Z-5l5wK:
23.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		9 / 10 THR K   1
ALA K  20
THR K  21
ALA K  22
ALA K  27
VAL K  31
LYS K  33
GLY K  47
ALA K  49
 None
 0.73A 2f16Y-5l5wK:
23.7
2f16Z-5l5wK:
23.4		 2f16Y-5l5wK:
82.55
2f16Z-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 12 THR K   1
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.83A 3mg02-5l5wK:
28.6
3mg0V-5l5wK:
29.2		 3mg02-5l5wK:
28.37
3mg0V-5l5wK:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   2
THR K   1
SER K 173
GLY K 172
ALA K 164
 None
 0.89A 3mg02-5l5wK:
28.6
3mg0V-5l5wK:
29.2		 3mg02-5l5wK:
28.37
3mg0V-5l5wK:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.40A 3mg0H-5l5wK:
29.1
3mg0I-5l5wK:
25.3		 3mg0H-5l5wK:
29.91
3mg0I-5l5wK:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.71A 3mg0H-5l5wK:
29.1
3mg0I-5l5wK:
25.3		 3mg0H-5l5wK:
29.91
3mg0I-5l5wK:
23.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		10 / 11 THR K   1
ALA K  20
THR K  21
ALA K  27
VAL K  31
LYS K  33
ALA K  46
GLY K  47
ALA K  49
SER K 130
 None
 0.67A 3mg0K-5l5wK:
37.2
3mg0L-5l5wK:
23.7		 3mg0K-5l5wK:
82.55
3mg0L-5l5wK:
23.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 11 THR K   1
THR K  21
ALA K  22
ALA K  46
GLY K  47
SER K 130
 None
 1.32A 3mg0K-5l5wK:
37.2
3mg0L-5l5wK:
23.7		 3mg0K-5l5wK:
82.55
3mg0L-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
ALA K  27
LYS K  33
GLY K  47
 None
 0.59A 3mg0N-5l5wK:
28.7		 3mg0N-5l5wK:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.78A 3mg0N-5l5wK:
28.7		 3mg0N-5l5wK:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   2
THR K   1
SER K 173
GLY K 172
ALA K 164
 None
 0.87A 3mg0N-5l5wK:
28.7		 3mg0N-5l5wK:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
ALA K  27
LYS K  33
ALA K  46
GLY K  47
 None
 0.61A 3mg0V-5l5wK:
29.2
3mg0W-5l5wK:
25.3		 3mg0V-5l5wK:
29.91
3mg0W-5l5wK:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.44A 3mg0V-5l5wK:
29.2
3mg0W-5l5wK:
25.3		 3mg0V-5l5wK:
29.91
3mg0W-5l5wK:
23.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 ALA K  20
ALA K  22
ALA K  27
VAL K  31
GLY K  48
 None
 0.74A 3mg0Y-5l5wK:
23.8
3mg0Z-5l5wK:
23.3		 3mg0Y-5l5wK:
82.55
3mg0Z-5l5wK:
23.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		11 / 12 THR K   1
ALA K  20
THR K  21
ALA K  22
ALA K  27
VAL K  31
LYS K  33
ALA K  46
GLY K  47
ALA K  49
SER K 130
 None
 0.68A 3mg0Y-5l5wK:
23.8
3mg0Z-5l5wK:
23.3		 3mg0Y-5l5wK:
82.55
3mg0Z-5l5wK:
23.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 12 THR K   1
THR K  21
ALA K  22
ALA K  46
GLY K  47
SER K 130
 None
 1.28A 3mg0Y-5l5wK:
23.8
3mg0Z-5l5wK:
23.3		 3mg0Y-5l5wK:
82.55
3mg0Z-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U52_A_CUA515_0
(PHENOL HYDROXYLASE
COMPONENT PHL
PHENOL HYDROXYLASE
COMPONENT PHN)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 HIS K 178
HIS K 187
ILE K 185
 None
 0.85A 3u52A-5l5wK:
undetectable
3u52C-5l5wK:
undetectable		 3u52A-5l5wK:
19.16
3u52C-5l5wK:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.73A 4qvlV-5l5wK:
29.2
4qvlb-5l5wK:
28.8		 4qvlV-5l5wK:
29.61
4qvlb-5l5wK:
28.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		8 / 11 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.69A 4qvlK-5l5wK:
37.8
4qvlL-5l5wK:
23.8		 4qvlK-5l5wK:
82.55
4qvlL-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.72A 4qvlH-5l5wK:
27.5
4qvlN-5l5wK:
28.8		 4qvlH-5l5wK:
29.61
4qvlN-5l5wK:
28.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		8 / 11 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.70A 4qvlY-5l5wK:
24.1
4qvlZ-5l5wK:
23.6		 4qvlY-5l5wK:
82.55
4qvlZ-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.75A 4qvmV-5l5wK:
29.3
4qvmb-5l5wK:
28.8		 4qvmV-5l5wK:
29.61
4qvmb-5l5wK:
28.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		8 / 9 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.69A 4qvmK-5l5wK:
37.6
4qvmL-5l5wK:
23.7		 4qvmK-5l5wK:
82.08
4qvmL-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.74A 4qvmH-5l5wK:
27.6
4qvmN-5l5wK:
28.8		 4qvmH-5l5wK:
29.61
4qvmN-5l5wK:
28.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		8 / 10 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.69A 4qvmY-5l5wK:
29.5
4qvmZ-5l5wK:
23.5		 4qvmY-5l5wK:
82.08
4qvmZ-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 12 THR K   1
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.80A 4qvnV-5l5wK:
29.1
4qvnb-5l5wK:
28.8		 4qvnV-5l5wK:
29.61
4qvnb-5l5wK:
28.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		7 / 9 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.73A 4qvnK-5l5wK:
37.6
4qvnL-5l5wK:
23.7		 4qvnK-5l5wK:
82.08
4qvnL-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 12 THR K   1
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.80A 4qvnH-5l5wK:
27.5
4qvnN-5l5wK:
28.8		 4qvnH-5l5wK:
29.61
4qvnN-5l5wK:
28.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		7 / 9 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.72A 4qvnY-5l5wK:
24.0
4qvnZ-5l5wK:
23.5		 4qvnY-5l5wK:
82.08
4qvnZ-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.74A 4qvpV-5l5wK:
29.1
4qvpb-5l5wK:
28.8		 4qvpV-5l5wK:
29.61
4qvpb-5l5wK:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.43A 4qvpH-5l5wK:
27.5
4qvpI-5l5wK:
25.3		 4qvpH-5l5wK:
29.61
4qvpI-5l5wK:
23.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		8 / 10 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.71A 4qvpK-5l5wK:
37.7
4qvpL-5l5wK:
23.5		 4qvpK-5l5wK:
82.08
4qvpL-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.73A 4qvpH-5l5wK:
27.5
4qvpN-5l5wK:
28.8		 4qvpH-5l5wK:
29.61
4qvpN-5l5wK:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.42A 4qvpV-5l5wK:
29.1
4qvpW-5l5wK:
25.4		 4qvpV-5l5wK:
29.61
4qvpW-5l5wK:
23.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		8 / 10 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.71A 4qvpY-5l5wK:
24.0
4qvpZ-5l5wK:
23.5		 4qvpY-5l5wK:
82.08
4qvpZ-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.76A 4qvqV-5l5wK:
29.2
4qvqb-5l5wK:
28.7		 4qvqV-5l5wK:
29.61
4qvqb-5l5wK:
28.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		7 / 9 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.72A 4qvqK-5l5wK:
37.4
4qvqL-5l5wK:
23.7		 4qvqK-5l5wK:
82.08
4qvqL-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.75A 4qvqH-5l5wK:
27.5
4qvqN-5l5wK:
28.8		 4qvqH-5l5wK:
29.61
4qvqN-5l5wK:
28.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		7 / 9 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.70A 4qvqY-5l5wK:
29.3
4qvqZ-5l5wK:
23.5		 4qvqY-5l5wK:
82.08
4qvqZ-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.43A 4qvvH-5l5wK:
27.6		 4qvvH-5l5wK:
29.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
ALA K  46
GLY K  47
 None
 0.69A 4qvvH-5l5wK:
27.6		 4qvvH-5l5wK:
29.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVV_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 8 THR K   1
THR K  21
LYS K  33
GLY K  47
GLY K  48
 None
 0.60A 4qvvK-5l5wK:
37.8
4qvvL-5l5wK:
23.7		 4qvvK-5l5wK:
82.08
4qvvL-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.43A 4qvvV-5l5wK:
29.2		 4qvvV-5l5wK:
29.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVV_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 8 THR K   1
THR K  21
LYS K  33
GLY K  47
GLY K  48
 None
 0.60A 4qvvY-5l5wK:
29.6
4qvvZ-5l5wK:
23.5		 4qvvY-5l5wK:
82.08
4qvvZ-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.72A 4qvwV-5l5wK:
29.2
4qvwb-5l5wK:
28.8		 4qvwV-5l5wK:
29.61
4qvwb-5l5wK:
28.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		7 / 11 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
 None
 0.63A 4qvwK-5l5wK:
37.9
4qvwL-5l5wK:
23.7		 4qvwK-5l5wK:
82.08
4qvwL-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.71A 4qvwH-5l5wK:
27.6
4qvwN-5l5wK:
28.8		 4qvwH-5l5wK:
29.61
4qvwN-5l5wK:
28.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		7 / 11 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
 None
 0.62A 4qvwY-5l5wK:
29.7
4qvwZ-5l5wK:
23.6		 4qvwY-5l5wK:
82.08
4qvwZ-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.42A 4qvyH-5l5wK:
27.6		 4qvyH-5l5wK:
29.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
ALA K  46
GLY K  47
 None
 0.67A 4qvyH-5l5wK:
27.6		 4qvyH-5l5wK:
29.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 10 ALA K  20
THR K  21
VAL K  31
LYS K  33
GLY K  47
 None
 0.83A 4qvyK-5l5wK:
38.1
4qvyL-5l5wK:
23.8		 4qvyK-5l5wK:
82.08
4qvyL-5l5wK:
23.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		8 / 10 THR K   1
ALA K  20
THR K  21
ALA K  22
ALA K  27
VAL K  31
LYS K  33
GLY K  48
 None
 0.60A 4qvyK-5l5wK:
38.1
4qvyL-5l5wK:
23.8		 4qvyK-5l5wK:
82.08
4qvyL-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.43A 4qvyV-5l5wK:
29.3
4qvyW-5l5wK:
25.4		 4qvyV-5l5wK:
29.61
4qvyW-5l5wK:
23.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 10 ALA K  20
THR K  21
VAL K  31
LYS K  33
GLY K  47
 None
 0.83A 4qvyY-5l5wK:
29.8
4qvyZ-5l5wK:
23.5		 4qvyY-5l5wK:
82.08
4qvyZ-5l5wK:
23.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		8 / 10 THR K   1
ALA K  20
THR K  21
ALA K  22
ALA K  27
VAL K  31
LYS K  33
GLY K  48
 None
 0.61A 4qvyY-5l5wK:
29.8
4qvyZ-5l5wK:
23.5		 4qvyY-5l5wK:
82.08
4qvyZ-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.73A 4qw0V-5l5wK:
29.2
4qw0b-5l5wK:
28.8		 4qw0V-5l5wK:
29.61
4qw0b-5l5wK:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.42A 4qw0H-5l5wK:
27.6
4qw0I-5l5wK:
25.3		 4qw0H-5l5wK:
29.61
4qw0I-5l5wK:
23.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 7 THR K   1
ALA K  20
THR K  21
ALA K  22
LYS K  33
 None
 0.41A 4qw0K-5l5wK:
38.0		 4qw0K-5l5wK:
81.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.72A 4qw0H-5l5wK:
27.6
4qw0N-5l5wK:
28.8		 4qw0H-5l5wK:
29.61
4qw0N-5l5wK:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.42A 4qw0V-5l5wK:
29.2
4qw0W-5l5wK:
25.3		 4qw0V-5l5wK:
29.61
4qw0W-5l5wK:
23.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 7 THR K   1
ALA K  20
THR K  21
ALA K  22
LYS K  33
 None
 0.42A 4qw0Y-5l5wK:
29.8		 4qw0Y-5l5wK:
81.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.76A 4qw1V-5l5wK:
29.1
4qw1b-5l5wK:
28.8		 4qw1V-5l5wK:
29.61
4qw1b-5l5wK:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.43A 4qw1H-5l5wK:
27.5
4qw1I-5l5wK:
25.4		 4qw1H-5l5wK:
29.61
4qw1I-5l5wK:
23.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		8 / 11 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.72A 4qw1K-5l5wK:
37.8
4qw1L-5l5wK:
23.8		 4qw1K-5l5wK:
82.08
4qw1L-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.75A 4qw1H-5l5wK:
27.5
4qw1N-5l5wK:
28.8		 4qw1H-5l5wK:
29.61
4qw1N-5l5wK:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.43A 4qw1V-5l5wK:
29.1
4qw1W-5l5wK:
25.3		 4qw1V-5l5wK:
29.61
4qw1W-5l5wK:
23.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		8 / 10 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.71A 4qw1Y-5l5wK:
24.1
4qw1Z-5l5wK:
23.6		 4qw1Y-5l5wK:
82.08
4qw1Z-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.74A 4qw3V-5l5wK:
29.2
4qw3b-5l5wK:
28.8		 4qw3V-5l5wK:
29.61
4qw3b-5l5wK:
28.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		8 / 10 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.69A 4qw3K-5l5wK:
37.4
4qw3L-5l5wK:
23.7		 4qw3K-5l5wK:
82.08
4qw3L-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.74A 4qw3H-5l5wK:
27.6
4qw3N-5l5wK:
28.8		 4qw3H-5l5wK:
29.61
4qw3N-5l5wK:
28.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		8 / 10 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.70A 4qw3Y-5l5wK:
29.3
4qw3Z-5l5wK:
23.4		 4qw3Y-5l5wK:
82.08
4qw3Z-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.77A 4qwuV-5l5wK:
29.1
4qwub-5l5wK:
28.7		 4qwuV-5l5wK:
29.61
4qwub-5l5wK:
28.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QWU_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 9 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
 None
 0.58A 4qwuK-5l5wK:
36.9
4qwuL-5l5wK:
23.6		 4qwuK-5l5wK:
82.08
4qwuL-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.77A 4qwuH-5l5wK:
27.5
4qwuN-5l5wK:
28.7		 4qwuH-5l5wK:
29.61
4qwuN-5l5wK:
28.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QWU_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		7 / 9 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
MET K  45
GLY K  47
 None
 0.85A 4qwuY-5l5wK:
24.1
4qwuZ-5l5wK:
23.6		 4qwuY-5l5wK:
82.08
4qwuZ-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDQ_A_BEZA306_0
(GLYCOSIDE HYDROLASE
FAMILY PROTEIN)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 ARG K   9
ASP K 146
TRP K 145
 None
 0.93A 4xdqA-5l5wK:
undetectable		 4xdqA-5l5wK:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_C_HISC302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 10 GLY K  11
VAL K  12
VAL K 179
LEU K 153
LEU K  42
 None
 1.32A 4yb6C-5l5wK:
undetectable
4yb6F-5l5wK:
undetectable		 4yb6C-5l5wK:
21.81
4yb6F-5l5wK:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_D_HISD302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 10 LEU K 153
LEU K  42
GLY K  11
VAL K  12
VAL K 179
 None
 1.33A 4yb6A-5l5wK:
undetectable
4yb6D-5l5wK:
undetectable		 4yb6A-5l5wK:
21.81
4yb6D-5l5wK:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.73A 5bxnV-5l5wK:
29.1
5bxnb-5l5wK:
28.8		 5bxnV-5l5wK:
29.18
5bxnb-5l5wK:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.43A 5bxnH-5l5wK:
29.0
5bxnI-5l5wK:
25.5		 5bxnH-5l5wK:
29.18
5bxnI-5l5wK:
23.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		8 / 11 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.69A 5bxnK-5l5wK:
37.7
5bxnL-5l5wK:
23.5		 5bxnK-5l5wK:
82.55
5bxnL-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.72A 5bxnH-5l5wK:
29.0
5bxnN-5l5wK:
28.8		 5bxnH-5l5wK:
29.18
5bxnN-5l5wK:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.40A 5bxnV-5l5wK:
29.1
5bxnW-5l5wK:
25.4		 5bxnV-5l5wK:
29.18
5bxnW-5l5wK:
23.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		8 / 11 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.70A 5bxnY-5l5wK:
24.0
5bxnZ-5l5wK:
23.5		 5bxnY-5l5wK:
82.55
5bxnZ-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.74A 5cz7H-5l5wK:
27.6
5cz7N-5l5wK:
28.8		 5cz7H-5l5wK:
29.61
5cz7N-5l5wK:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.43A 5cz7V-5l5wK:
29.2
5cz7W-5l5wK:
25.4		 5cz7V-5l5wK:
29.61
5cz7W-5l5wK:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.73A 5d0xV-5l5wK:
29.3
5d0xb-5l5wK:
28.8		 5d0xV-5l5wK:
29.61
5d0xb-5l5wK:
28.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		7 / 9 ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.73A 5d0xK-5l5wK:
37.6
5d0xL-5l5wK:
23.8		 5d0xK-5l5wK:
82.08
5d0xL-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.73A 5d0xH-5l5wK:
27.6
5d0xN-5l5wK:
28.8		 5d0xH-5l5wK:
29.61
5d0xN-5l5wK:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.43A 5d0xV-5l5wK:
29.3		 5d0xV-5l5wK:
29.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
ALA K  46
GLY K  47
 None
 0.69A 5d0xV-5l5wK:
29.3		 5d0xV-5l5wK:
29.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		7 / 9 ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.73A 5d0xY-5l5wK:
29.5
5d0xZ-5l5wK:
23.5		 5d0xY-5l5wK:
82.08
5d0xZ-5l5wK:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 12 LEU K  59
THR K  99
GLY K  43
ILE K 101
GLY K 129
 None
 0.88A 5d4uC-5l5wK:
undetectable		 5d4uC-5l5wK:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 12 LEU K  59
THR K  99
GLY K  43
ILE K 101
GLY K 129
 None
 0.84A 5d4uD-5l5wK:
undetectable		 5d4uD-5l5wK:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQY_A_BEZA401_0
(THIOREDOXIN)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		4 / 8 ILE K  13
LYS K   7
VAL K  14
CYH K 102
 None
 1.07A 5dqyA-5l5wK:
undetectable		 5dqyA-5l5wK:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_B_010B607_0
(HNL ISOENZYME 5)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 10 ALA K 162
ALA K 164
VAL K 192
LEU K   4
VAL K 174
 None
 1.35A 5eb5B-5l5wK:
undetectable		 5eb5B-5l5wK:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 12 THR K 125
ALA K  15
LEU K 195
GLY K 156
SER K 159
 None
 1.12A 5jglB-5l5wK:
undetectable		 5jglB-5l5wK:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.41A 5l5fH-5l5wK:
27.6
5l5fI-5l5wK:
25.4		 5l5fH-5l5wK:
29.61
5l5fI-5l5wK:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.40A 5l5fV-5l5wK:
29.2
5l5fW-5l5wK:
25.4		 5l5fV-5l5wK:
29.61
5l5fW-5l5wK:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.73A 5l5zV-5l5wK:
29.3
5l5zb-5l5wK:
28.7		 5l5zV-5l5wK:
29.61
5l5zb-5l5wK:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   2
THR K   1
SER K 173
GLY K 172
ALA K 164
 None
 0.90A 5l5zV-5l5wK:
29.3
5l5zb-5l5wK:
28.7		 5l5zV-5l5wK:
29.61
5l5zb-5l5wK:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.40A 5l5zH-5l5wK:
27.6
5l5zI-5l5wK:
25.5		 5l5zH-5l5wK:
29.61
5l5zI-5l5wK:
23.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		8 / 9 THR K   1
ALA K  20
THR K  21
ALA K  22
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.50A 5l5zK-5l5wK:
39.5
5l5zL-5l5wK:
23.6		 5l5zK-5l5wK:
100.00
5l5zL-5l5wK:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.73A 5l5zH-5l5wK:
27.6
5l5zN-5l5wK:
28.8		 5l5zH-5l5wK:
29.61
5l5zN-5l5wK:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   2
THR K   1
SER K 173
GLY K 172
ALA K 164
 None
 0.90A 5l5zH-5l5wK:
27.6
5l5zN-5l5wK:
28.8		 5l5zH-5l5wK:
29.61
5l5zN-5l5wK:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.39A 5l5zV-5l5wK:
29.3
5l5zW-5l5wK:
25.5		 5l5zV-5l5wK:
29.61
5l5zW-5l5wK:
23.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		8 / 9 THR K   1
ALA K  20
THR K  21
ALA K  22
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.51A 5l5zY-5l5wK:
39.5
5l5zZ-5l5wK:
23.6		 5l5zY-5l5wK:
100.00
5l5zZ-5l5wK:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.71A 5l66V-5l5wK:
29.3
5l66b-5l5wK:
28.8		 5l66V-5l5wK:
29.61
5l66b-5l5wK:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.40A 5l66H-5l5wK:
27.6
5l66I-5l5wK:
25.5		 5l66H-5l5wK:
29.61
5l66I-5l5wK:
23.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 10 THR K   1
ALA K  20
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.58A 5l66K-5l5wK:
38.3
5l66L-5l5wK:
23.8		 5l66K-5l5wK:
84.36
5l66L-5l5wK:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.72A 5l66H-5l5wK:
27.6
5l66N-5l5wK:
28.8		 5l66H-5l5wK:
29.61
5l66N-5l5wK:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.40A 5l66V-5l5wK:
29.3
5l66W-5l5wK:
25.4		 5l66V-5l5wK:
29.61
5l66W-5l5wK:
23.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 10 THR K   1
ALA K  20
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.59A 5l66Y-5l5wK:
38.3
5l66Z-5l5wK:
23.6		 5l66Y-5l5wK:
84.36
5l66Z-5l5wK:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.83A 5lf3b-5l5wK:
28.5		 5lf3b-5l5wK:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   2
THR K   1
SER K 173
GLY K 172
ALA K 164
 None
 0.91A 5lf3b-5l5wK:
28.5		 5lf3b-5l5wK:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 10 THR K   1
ALA K  20
THR K  21
ALA K  46
GLY K  47
ALA K  49
 None
 0.77A 5lf3H-5l5wK:
30.0
5lf3I-5l5wK:
25.3		 5lf3H-5l5wK:
27.35
5lf3I-5l5wK:
22.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		8 / 11 THR K   1
ALA K  20
THR K  21
ALA K  22
LYS K  33
GLY K  47
ALA K  49
TYR K 169
 None
 0.69A 5lf3K-5l5wK:
36.0
5lf3L-5l5wK:
24.7		 5lf3K-5l5wK:
83.09
5lf3L-5l5wK:
24.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		8 / 11 THR K   1
ALA K  20
THR K  21
LYS K  33
GLY K  47
GLY K  48
ALA K  49
TYR K 169
 None
 0.75A 5lf3K-5l5wK:
36.0
5lf3L-5l5wK:
24.7		 5lf3K-5l5wK:
83.09
5lf3L-5l5wK:
24.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 11 THR K   1
ALA K  20
THR K  21
LYS K  33
GLY K  47
TYR K 169
 None
 0.98A 5lf3K-5l5wK:
36.0
5lf3L-5l5wK:
24.7		 5lf3K-5l5wK:
83.09
5lf3L-5l5wK:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.82A 5lf3N-5l5wK:
28.6		 5lf3N-5l5wK:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   2
THR K   1
SER K 173
GLY K 172
ALA K 164
 None
 0.92A 5lf3N-5l5wK:
28.6		 5lf3N-5l5wK:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		7 / 10 THR K   1
ALA K  20
THR K  21
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.72A 5lf3V-5l5wK:
30.0
5lf3W-5l5wK:
25.4		 5lf3V-5l5wK:
27.35
5lf3W-5l5wK:
22.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		8 / 11 THR K   1
ALA K  20
THR K  21
ALA K  22
LYS K  33
GLY K  47
ALA K  49
TYR K 169
 None
 0.68A 5lf3Y-5l5wK:
36.0
5lf3Z-5l5wK:
24.7		 5lf3Y-5l5wK:
83.09
5lf3Z-5l5wK:
24.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		8 / 11 THR K   1
ALA K  20
THR K  21
LYS K  33
GLY K  47
GLY K  48
ALA K  49
TYR K 169
 None
 0.74A 5lf3Y-5l5wK:
36.0
5lf3Z-5l5wK:
24.7		 5lf3Y-5l5wK:
83.09
5lf3Z-5l5wK:
24.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 11 THR K   1
ALA K  20
THR K  21
LYS K  33
GLY K  47
TYR K 169
 None
 0.96A 5lf3Y-5l5wK:
36.0
5lf3Z-5l5wK:
24.7		 5lf3Y-5l5wK:
83.09
5lf3Z-5l5wK:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 12 THR K   1
THR K  21
ALA K  27
LYS K  33
GLY K  47
 None
 0.65A 5lf7V-5l5wK:
30.0
5lf7b-5l5wK:
28.6		 5lf7V-5l5wK:
27.35
5lf7b-5l5wK:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		6 / 12 TYR K 134
THR K   2
THR K   1
SER K 173
GLY K 172
ALA K 164
 None
 1.28A 5lf7V-5l5wK:
30.0
5lf7b-5l5wK:
28.6		 5lf7V-5l5wK:
27.35
5lf7b-5l5wK:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 11 THR K   1
ALA K  20
ALA K  46
GLY K  47
ALA K  49
 None
 0.64A 5lf7H-5l5wK:
30.0
5lf7I-5l5wK:
25.3		 5lf7H-5l5wK:
27.35
5lf7I-5l5wK:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 11 THR K   1
ALA K  20
THR K  21
ALA K  46
GLY K  47
 None
 0.61A 5lf7H-5l5wK:
30.0
5lf7I-5l5wK:
25.3		 5lf7H-5l5wK:
27.35
5lf7I-5l5wK:
22.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		7 / 11 THR K   1
ALA K  20
THR K  21
ALA K  22
VAL K  31
LYS K  33
GLY K  47
 None
 0.53A 5lf7K-5l5wK:
35.7
5lf7L-5l5wK:
24.7		 5lf7K-5l5wK:
83.09
5lf7L-5l5wK:
24.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		6 / 11 THR K   1
ALA K  20
THR K  21
VAL K  31
LYS K  33
GLY K  47
 None
 1.01A 5lf7K-5l5wK:
35.7
5lf7L-5l5wK:
24.7		 5lf7K-5l5wK:
83.09
5lf7L-5l5wK:
24.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		7 / 11 THR K   1
ALA K  20
VAL K  31
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.59A 5lf7K-5l5wK:
35.7
5lf7L-5l5wK:
24.7		 5lf7K-5l5wK:
83.09
5lf7L-5l5wK:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 12 THR K   1
THR K  21
ALA K  27
LYS K  33
GLY K  47
 None
 0.62A 5lf7H-5l5wK:
30.0
5lf7N-5l5wK:
28.6		 5lf7H-5l5wK:
27.35
5lf7N-5l5wK:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		6 / 12 TYR K 134
THR K   2
THR K   1
SER K 173
GLY K 172
ALA K 164
 None
 1.30A 5lf7H-5l5wK:
30.0
5lf7N-5l5wK:
28.6		 5lf7H-5l5wK:
27.35
5lf7N-5l5wK:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 11 THR K   1
ALA K  20
ALA K  46
GLY K  47
ALA K  49
 None
 0.61A 5lf7V-5l5wK:
30.0
5lf7W-5l5wK:
25.4		 5lf7V-5l5wK:
27.35
5lf7W-5l5wK:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 11 THR K   1
ALA K  20
THR K  21
ALA K  46
GLY K  47
 None
 0.59A 5lf7V-5l5wK:
30.0
5lf7W-5l5wK:
25.4		 5lf7V-5l5wK:
27.35
5lf7W-5l5wK:
22.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		7 / 11 THR K   1
ALA K  20
THR K  21
ALA K  22
VAL K  31
LYS K  33
GLY K  47
 None
 0.53A 5lf7Y-5l5wK:
35.8
5lf7Z-5l5wK:
24.7		 5lf7Y-5l5wK:
83.09
5lf7Z-5l5wK:
24.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		6 / 11 THR K   1
ALA K  20
THR K  21
VAL K  31
LYS K  33
GLY K  47
 None
 0.99A 5lf7Y-5l5wK:
35.8
5lf7Z-5l5wK:
24.7		 5lf7Y-5l5wK:
83.09
5lf7Z-5l5wK:
24.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		7 / 11 THR K   1
ALA K  20
VAL K  31
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.60A 5lf7Y-5l5wK:
35.8
5lf7Z-5l5wK:
24.7		 5lf7Y-5l5wK:
83.09
5lf7Z-5l5wK:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		6 / 12 THR K   1
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.80A 6hwdV-5l5wK:
29.1
6hwdb-5l5wK:
28.7		 6hwdV-5l5wK:
22.88
6hwdb-5l5wK:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		6 / 12 THR K   1
ALA K  27
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.70A 6hwdH-5l5wK:
27.5
6hwdI-5l5wK:
25.4		 6hwdH-5l5wK:
22.88
6hwdI-5l5wK:
17.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		9 / 11 THR K   1
ALA K  20
THR K  21
ALA K  22
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.83A 6hwdK-5l5wK:
36.9
6hwdL-5l5wK:
23.8		 6hwdK-5l5wK:
78.75
6hwdL-5l5wK:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		6 / 12 THR K   1
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.81A 6hwdH-5l5wK:
27.5
6hwdN-5l5wK:
28.7		 6hwdH-5l5wK:
22.88
6hwdN-5l5wK:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		6 / 11 THR K   1
ALA K  27
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.70A 6hwdV-5l5wK:
29.1		 6hwdV-5l5wK:
22.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5l5w PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		9 / 11 THR K   1
ALA K  20
THR K  21
ALA K  22
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.84A 6hwdY-5l5wK:
23.5
6hwdZ-5l5wK:
23.6		 6hwdY-5l5wK:
78.75
6hwdZ-5l5wK:
18.95