SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5l7s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)
5l7s SECRETED RXLR
EFFECTOR PEPTIDE
PROTEIN

(Phytophthora
infestans)
3 / 3 ASP A 254
LEU A 278
LEU A 291
None
0.75A 1np1B-5l7sA:
undetectable
1np1B-5l7sA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)
5l7s SECRETED RXLR
EFFECTOR PEPTIDE
PROTEIN

(Phytophthora
infestans)
3 / 3 GLU A 315
ARG A 279
HIS A 276
None
0.85A 4kf9A-5l7sA:
undetectable
4kf9A-5l7sA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_1
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)
5l7s SECRETED RXLR
EFFECTOR PEPTIDE
PROTEIN

(Phytophthora
infestans)
5 / 12 GLY A 253
PHE A 252
PHE A 233
LEU A 274
ASP A 254
None
1.13A 5nknA-5l7sA:
undetectable
5nknA-5l7sA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
5l7s SECRETED RXLR
EFFECTOR PEPTIDE
PROTEIN

(Phytophthora
infestans)
3 / 3 GLN A 137
TRP A 106
VAL A 105
None
1.16A 6auuA-5l7sA:
undetectable
6auuA-5l7sA:
21.19