SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5l7v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		4 / 5 GLY A 168
LEU A  84
THR A  85
VAL A  81
 None
 0.97A 1ekjF-5l7vA:
undetectable
1ekjG-5l7vA:
undetectable		 1ekjF-5l7vA:
16.76
1ekjG-5l7vA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_1
(PROTEASE)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		4 / 7 ASP A 379
ILE A 355
ALA A 359
ILE A 358
 None
 0.77A 1n49A-5l7vA:
undetectable		 1n49A-5l7vA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 TRP A 448
THR A 428
TYR A 426
 None
 0.91A 2a3aA-5l7vA:
4.7		 2a3aA-5l7vA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 TRP A 448
THR A 428
TYR A 426
 None
 0.96A 2a3aB-5l7vA:
8.0		 2a3aB-5l7vA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 TRP A 448
THR A 428
TYR A 426
 None
 0.95A 2a3bA-5l7vA:
5.2		 2a3bA-5l7vA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		5 / 12 VAL A 243
PHE A 282
PHE A 343
LEU A 347
SER A 385
 None
 1.42A 3apvA-5l7vA:
undetectable		 3apvA-5l7vA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		5 / 11 ALA A 200
ILE A 507
GLU A 511
ALA A 450
ASP A 459
 None
 1.10A 3nmuB-5l7vA:
undetectable
3nmuJ-5l7vA:
undetectable		 3nmuB-5l7vA:
20.58
3nmuJ-5l7vA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_D_ACTD4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		4 / 5 LEU A 500
LEU A 203
GLY A 240
THR A 504
 None
 0.80A 3si7C-5l7vA:
undetectable
3si7D-5l7vA:
undetectable		 3si7C-5l7vA:
20.36
3si7D-5l7vA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 SER A 497
TYR A 491
PRO A 443
 None
 0.80A 4k8cA-5l7vA:
2.1		 4k8cA-5l7vA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 SER A 497
TYR A 491
PRO A 443
 None
 0.79A 4kahA-5l7vA:
2.1		 4kahA-5l7vA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 SER A 497
TYR A 491
PRO A 443
 None
 0.80A 4kahB-5l7vA:
undetectable		 4kahB-5l7vA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 SER A 497
TYR A 491
PRO A 443
 None
 0.80A 4kanA-5l7vA:
undetectable		 4kanA-5l7vA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 SER A 497
TYR A 491
PRO A 443
 None
 0.80A 4kbeA-5l7vA:
undetectable		 4kbeA-5l7vA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 SER A 497
TYR A 491
PRO A 443
 None
 0.81A 4lbgA-5l7vA:
undetectable		 4lbgA-5l7vA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 SER A 497
TYR A 491
PRO A 443
 None
 0.80A 4lbgB-5l7vA:
undetectable		 4lbgB-5l7vA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		5 / 12 TYR A 491
VAL A 130
ALA A 131
SER A 497
THR A 106
 None
 1.20A 4mm4B-5l7vA:
undetectable		 4mm4B-5l7vA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		5 / 12 TYR A 491
VAL A 130
ALA A 131
SER A 497
THR A 106
 None
 1.22A 4mm6A-5l7vA:
undetectable		 4mm6A-5l7vA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		5 / 11 TYR A 491
VAL A 130
ALA A 131
SER A 497
THR A 106
 None
 1.18A 4mmaA-5l7vA:
undetectable		 4mmaA-5l7vA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		5 / 12 LEU A 462
GLN A 297
THR A 245
TYR A 301
GLN A 207
 None
 1.37A 4ng6A-5l7vA:
undetectable		 4ng6A-5l7vA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_B_ACTB401_0
(3C-LIKE PROTEINASE)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 ARG A 499
ASP A 132
TYR A 488
 None
 0.93A 4yo9B-5l7vA:
undetectable		 4yo9B-5l7vA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DL9_A_ACTA214_0
(LYSOZYME C)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		4 / 5 GLU A  60
TRP A  57
VAL A 188
ALA A  56
 None
 1.49A 5dl9A-5l7vA:
undetectable		 5dl9A-5l7vA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 LEU A 462
TYR A 301
SER A 385
 None
 0.89A 5iktA-5l7vA:
undetectable		 5iktA-5l7vA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		4 / 8 ILE A 529
ILE A 560
GLU A 511
ALA A 454
 None
 0.72A 5og9A-5l7vA:
undetectable		 5og9A-5l7vA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJY_A_BEZA304_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 MET A 368
GLU A 362
ARG A 363
 None
GNL  A 601 (-3.4A)
None
 0.98A 5tjyA-5l7vA:
undetectable		 5tjyA-5l7vA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB307_0
(WELO5)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 GLU A 219
HIS A 225
VAL A 218
 None
 0.86A 5trqB-5l7vA:
undetectable		 5trqB-5l7vA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA607_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5l7v GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		4 / 4 GLY A 113
ARG A 120
ASN A 110
LEU A 109
 None
 1.38A 6b58A-5l7vA:
undetectable		 6b58A-5l7vA:
22.52