SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5l7x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_PNTA901_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 5l7x MOUSE ANTIBODY FAB
FRAGMENT, IGG1-KAPPA
HEAVY CHAIN
(Mus
musculus) 		5 / 12 TYR H  27
THR H  30
GLY H  97
SER H 100
ASN H  52
 None
 1.46A 3hiiA-5l7xH:
undetectable		 3hiiA-5l7xH:
15.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 5l7x MOUSE ANTIBODY FAB
FRAGMENT, IGG1-KAPPA
HEAVY CHAIN
(Mus
musculus) 		4 / 5 VAL H   2
TYR H  27
ARG H  94
TYR H 102
 None
 0.31A 4m7kH-5l7xH:
26.1		 4m7kH-5l7xH:
65.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5l7x MOUSE ANTIBODY FAB
FRAGMENT, IGG1-KAPPA
HEAVY CHAIN
(Mus
musculus) 		4 / 6 LEU H  37
MET H  80
THR H  68
LEU H  69
 None
 1.08A 5x1fA-5l7xH:
undetectable
5x1fJ-5l7xH:
undetectable		 5x1fA-5l7xH:
18.04
5x1fJ-5l7xH:
15.42