SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5l7z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5l7z MATERNAL PROTEIN
EXUPERANTIA
(Drosophila
melanogaster) 		4 / 4 ALA A  55
VAL A  38
ALA A  56
HIS A  62
 None
 1.15A 1q23A-5l7zA:
undetectable		 1q23A-5l7zA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5l7z MATERNAL PROTEIN
EXUPERANTIA
(Drosophila
melanogaster) 		4 / 4 ALA A  55
VAL A  38
ALA A  56
HIS A  62
 None
 1.24A 1q23F-5l7zA:
undetectable		 1q23F-5l7zA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5l7z MATERNAL PROTEIN
EXUPERANTIA
(Drosophila
melanogaster) 		4 / 4 ALA A 265
VAL A  38
ALA A  56
HIS A  62
 None
 1.26A 1q23F-5l7zA:
undetectable		 1q23F-5l7zA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5l7z MATERNAL PROTEIN
EXUPERANTIA
(Drosophila
melanogaster) 		5 / 12 ILE A  40
SER A 164
ALA A 163
LEU A 116
ILE A 148
 None
 1.33A 2xkwB-5l7zA:
undetectable		 2xkwB-5l7zA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_1
(PROTEASE)		 5l7z MATERNAL PROTEIN
EXUPERANTIA
(Drosophila
melanogaster) 		5 / 12 ALA A 126
ILE A 133
THR A  58
PRO A  59
THR A  60
 None
 0.69A 3el4A-5l7zA:
undetectable		 3el4A-5l7zA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)		 5l7z MATERNAL PROTEIN
EXUPERANTIA
(Drosophila
melanogaster) 		4 / 5 LEU A 116
GLN A 121
LEU A 119
GLU A 120
 None
 1.15A 3h5gA-5l7zA:
undetectable
3h5gB-5l7zA:
undetectable		 3h5gA-5l7zA:
6.01
3h5gB-5l7zA:
6.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QT0_A_486A4_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5l7z MATERNAL PROTEIN
EXUPERANTIA
(Drosophila
melanogaster) 		4 / 4 LYS A 106
GLN A  53
ILE A 148
LEU A 116
 None
 1.25A 3qt0A-5l7zA:
undetectable		 3qt0A-5l7zA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QT0_A_486A4_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5l7z MATERNAL PROTEIN
EXUPERANTIA
(Drosophila
melanogaster) 		4 / 4 LYS A 106
GLN A  53
ILE A 148
LEU A 157
 None
 1.20A 3qt0A-5l7zA:
undetectable		 3qt0A-5l7zA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_B_SAMB801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 5l7z MATERNAL PROTEIN
EXUPERANTIA
(Drosophila
melanogaster) 		5 / 11 GLY A  44
VAL A  83
PRO A  69
TYR A  70
LEU A  94
 None
 1.25A 3v8vB-5l7zA:
undetectable		 3v8vB-5l7zA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5l7z MATERNAL PROTEIN
EXUPERANTIA
(Drosophila
melanogaster) 		5 / 12 PHE A  63
PHE A 115
VAL A  83
ALA A 261
SER A 262
 None
 1.46A 4a84A-5l7zA:
undetectable		 4a84A-5l7zA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CVT_B_ACTB200_0
(N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE)		 5l7z MATERNAL PROTEIN
EXUPERANTIA
(Drosophila
melanogaster) 		3 / 3 ASN A  74
ALA A  76
ARG A  80
 None
 0.54A 5cvtB-5l7zA:
undetectable		 5cvtB-5l7zA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 5l7z MATERNAL PROTEIN
EXUPERANTIA
(Drosophila
melanogaster) 		5 / 12 MET A 293
ILE A 297
ALA A 265
VAL A  36
ILE A 136
 None
 1.24A 5mlmA-5l7zA:
undetectable		 5mlmA-5l7zA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_1
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 5l7z MATERNAL PROTEIN
EXUPERANTIA
(Drosophila
melanogaster) 		4 / 5 GLY A  44
ASP A  49
MET A  48
GLN A 314
 None
 1.40A 5ubbA-5l7zA:
undetectable		 5ubbA-5l7zA:
20.00