SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5l80'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5l80 MATERNAL PROTEIN
EXUPERANTIA,MATERNAL
PROTEIN EXUPERANTIA
(Drosophila
melanogaster) 		4 / 4 ALA A  55
VAL A  38
ALA A  56
HIS A  62
 None
 1.15A 1q23A-5l80A:
undetectable		 1q23A-5l80A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5l80 MATERNAL PROTEIN
EXUPERANTIA,MATERNAL
PROTEIN EXUPERANTIA
(Drosophila
melanogaster) 		4 / 4 ALA A  55
VAL A  38
ALA A  56
HIS A  62
 None
 1.24A 1q23F-5l80A:
undetectable		 1q23F-5l80A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5l80 MATERNAL PROTEIN
EXUPERANTIA,MATERNAL
PROTEIN EXUPERANTIA
(Drosophila
melanogaster) 		4 / 4 ALA A 212
VAL A  38
ALA A  56
HIS A  62
 None
 1.26A 1q23F-5l80A:
undetectable		 1q23F-5l80A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5l80 MATERNAL PROTEIN
EXUPERANTIA,MATERNAL
PROTEIN EXUPERANTIA
(Drosophila
melanogaster) 		4 / 4 ALA A  55
VAL A  38
ALA A  56
HIS A  62
 None
 1.13A 1q23K-5l80A:
undetectable		 1q23K-5l80A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_1
(PROTEASE)		 5l80 MATERNAL PROTEIN
EXUPERANTIA,MATERNAL
PROTEIN EXUPERANTIA
(Drosophila
melanogaster) 		5 / 12 ALA A 126
ILE A 133
THR A  58
PRO A  59
THR A  60
 None
 0.71A 3el4A-5l80A:
undetectable		 3el4A-5l80A:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QT0_A_486A4_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5l80 MATERNAL PROTEIN
EXUPERANTIA,MATERNAL
PROTEIN EXUPERANTIA
(Drosophila
melanogaster) 		4 / 4 LYS A 106
GLN A  53
ILE A 148
LEU A 116
 None
 1.22A 3qt0A-5l80A:
undetectable		 3qt0A-5l80A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QT0_A_486A4_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5l80 MATERNAL PROTEIN
EXUPERANTIA,MATERNAL
PROTEIN EXUPERANTIA
(Drosophila
melanogaster) 		4 / 4 LYS A 106
GLN A  53
ILE A 148
LEU A 157
 None
 1.28A 3qt0A-5l80A:
undetectable		 3qt0A-5l80A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_B_SAMB801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 5l80 MATERNAL PROTEIN
EXUPERANTIA,MATERNAL
PROTEIN EXUPERANTIA
(Drosophila
melanogaster) 		5 / 11 GLY A  44
VAL A  83
PRO A  69
TYR A  70
LEU A  94
 None
 1.27A 3v8vB-5l80A:
undetectable		 3v8vB-5l80A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5l80 MATERNAL PROTEIN
EXUPERANTIA,MATERNAL
PROTEIN EXUPERANTIA
(Drosophila
melanogaster) 		5 / 12 PHE A  63
PHE A 115
VAL A  83
ALA A 208
SER A 209
 None
 1.43A 4a84A-5l80A:
undetectable		 4a84A-5l80A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 5l80 MATERNAL PROTEIN
EXUPERANTIA,MATERNAL
PROTEIN EXUPERANTIA
(Drosophila
melanogaster) 		5 / 10 LEU A 135
LEU A  28
ILE A  34
LEU A  35
LEU A 119
 None
 1.10A 4odoB-5l80A:
undetectable		 4odoB-5l80A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 5l80 MATERNAL PROTEIN
EXUPERANTIA,MATERNAL
PROTEIN EXUPERANTIA
(Drosophila
melanogaster) 		5 / 12 MET A 240
ILE A 244
ALA A 212
VAL A  36
ILE A 136
 None
 1.15A 5mlmA-5l80A:
undetectable		 5mlmA-5l80A:
24.72